The nature of soluble factors that regulate fibroblast proliferation have not been finally characterized. Our aim was to study the role of tumour necrosis factor α (TNF-α) and interleukin-1 (IL-1) in the suppressive activity of alveolar... more
project scheduling is very critical topic in project management. Resource constrained project scheduling problem (RCPSP) consists of activities that must be scheduled based on dependencies relationships and priorities of activities. In... more
In previous work we have presented the ZENTURIO experiment management system for performance and parameter studies of parallel and distributed applications on cluster and Grid architectures. In this paper we describe experiences of an... more
There are important distributed computing systems which are neither massive nor high performance. Examples are: telecommunications systems, transportation or power networks, embedded control systems (such as embedded electronics in... more
In a cloud environment where Storage is offered as a service, a client stores his data with a provider and pays as per the usage. Once the contract ends, the client, as the data owner, may like to see, due to privacy reasons and otherwise... more
The hemagglutinin-neuraminidase (HN) protein is the major antigenic determinant of the Mumps virus (MuV) and plays an important role in the viral infectious cycle through its hemagglutination/hemadsorption (HA/HD) and neuraminidase (NA)... more
Background: In normal human keratinocytes, a p53-like protein, DNp63a, also known as CUSP, is constitutively and abundantly expressed. The significant constitutive expression of DNp63a in stratified epithelium has been proposed to... more
Factory automation requires smart solutions, especially when a set of equipment, from different vendors, has to be interfaced to enable fast and flexible production. In this paper, a hardware /software (hw/sw) modeling approach and its... more
We define a subset krtUML of UML which is rich enough to express all behavioural modelling entities of UML used for real-time applications, covering such aspects as active objects, dynamic object creation and destruction, dynamically... more
In the launching effect, a moving object (the launcher) contacts a stationary object (the target), and upon contact, the launcher stops and the target begins moving in the same direction and at the same or slower velocity as previous... more
In this paper we consider a labor constrained scheduling problem LCSP which is a simpli cation of a practical problem arising in industry. Jobs are subject to precedence constraints and have speci ed processing times. Moreover, for each j... more
Factory automation requires smart solutions, especially when a set of equipment, from different vendors, has to be interfaced to enable fast and flexible production. In this paper, a hardware /software (hw/sw) modeling approach and its... more
This paper presents a proposal of a language, based on synchronous active objects that introduces the CSP primitives into Java. The proposal does not use channels to realise the inter-process communications, but is shown to offer the same... more
In the early stages of the building design process, during the programming and the proposal stages, both user activities and the building are in focus for the designer. In spite of this, today's CAD programs give no support for management... more
Randomized experiments in which the treatment of a unit can affect the outcomes of other units are becoming increasingly common in healthcare, economics, and in the social and information sciences. From a causal inference perspective, the... more
HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or... more
Semantic and object-oriented data models provide convenient constructs for the specification of objects, relationships, and operations. The vehicle of representation is a collection of abstractions which parallel the means by which humans... more
This thesis aims to set the foundations for the development of load-balancing algorithms for theactive objects model defined by ProActive in the context of large-scale networks (Grids).ProActive is an open-source Java middleware which... more
We present a contribution on dynamic load balancing for distributed and parallel object-oriented applications. We specially target on peer to peer systems and its capability to distribute parallel computation, which transfer large amount... more
The Mine Sweeping System is being developed for the sole purpose of efficiently detecting mines within a user defined area .It comprises of a Java application from the user end and a robot grid system which work together to form a fully... more
This paper presents a new Java oriented monitoring infrastructure that enables tools to observe, analyze and manipulate the execution of distributed Java applications independent of implementation details like instrumentation of monitored... more
A dynamic system is one which changes its configuration as it runs. It is a system into which we can drop new components which then cooperate with the existing ones. Such systems are necessarily built from reusable components, since as... more
BACKGROUND: RET proto-oncogene rearrangements (RET/PTC) are causative events in the pathogenesis of a subset of papillary thyroid cancer (PTC). The prevalence of RET/PTC varies in different countries and according to specific clinical... more
Actor-based modeling, with encapsulated active objects which communicate asynchronously, is generally recognized to be well-suited for representing concurrent and distributed systems. In this paper we discuss the actor-based language... more
Actor-based modeling, with encapsulated active objects which communicate asynchronously, is generally recognized to be well-suited for representing concurrent and distributed systems. In this paper we discuss the actor-based language... more
In this paper, we propose extended Rebeca as a tool-supported actor-based language for modeling and verifying of concurrent and distributed systems. We enrich Rebeca with a formal concept of components which integrates the message-driven... more
In this paper, we propose extended Rebeca as a tool-supported actor-based language for modeling and verifying of concurrent and distributed systems. We enrich Rebeca with a formal concept of components which integrates the message-driven... more
Actor-based modeling, with encapsulated active objects which communicate asynchronously, is generally recognized to be well-suited for representing concurrent and distributed systems. In this paper we discuss the actor-based language... more
In this paper, we propose extended Rebeca as a tool-supported actor-based language for modeling and verifying of concurrent and distributed systems. We enrich Rebeca with a formal concept of components which integrates the message-driven... more
In this paper, we propose extended Rebeca as a toolsupported actor-based language for modeling and verifying concurrent and distributed systems. We enrich Rebeca with a formal concept of components which integrates the message-driven... more
Rationale-Physiological changes (such as heart rate and respiration rate) associated with strong pharmacological stimuli could change the blood-oxygenation-level-dependent (BOLD) functional magnetic resonance imaging (fMRI) mapping... more
Workflow specification and enactment is a critical operation in e-science. In this paper we describe how an abstract workflow, specified by an end-user in the form of an Execution Plan, is instantiated within the ICENI environment through... more
We study the galaxy environment of active galaxies, radio-loud and radio-quiet quasars in the redshift range 0.1 ≤ z ≤ 0.25. We use APM galaxies in order to explore the local galaxy overdensity and the b J − R colour distribution of... more
We introduce in this paper a new approach for grid-enabled distributed frameworks designed for distributed simulation and computational steering, which can easily be used for general purpose processing. Previous research focused on the... more
We define a subset krtUML of UML which is rich enough to express all behavioural modelling entities of UML used for real-time applications, covering such aspects as active objects, dynamic object creation and destruction, dynamically... more
Finite-state verification provides software developers with a powerful tool to detect errors. Many different analysis techniques have been proposed and implemented, and the limited amount of empirical data available shows that the... more
Increasing use of networks and their complexity have complicated the task of security analysis. Accordingly, automatic verification approaches have received more attention recently. In this paper, we showed how an attacker might combine... more
The pervasiveness of Internet-based communication technologies is fostering new forms of distributed computing, namely, large-scale, highly decentralized computing and mobile computing. In this context, new application domains such as... more
Although mobile agents and their supporting infrastructures have been extensively developed, it is still an emerging technology. A wider acceptance of mobile agents would be facilitated with the exploitation of suitable methodologies and... more
Typical Grid environments are characterized by a two-level scheduling: super and local scheduling. While the former regards the selection of proper resources to execute high level tasks, the latter regards the scheduling of tasks to... more
Target tracking is an attempt to estimate parameters that are changing with time. Traditionally, multi-target tracking systems utilize algorithms like Kalman filter and its derivatives Probabilistic Data Association Filter (PDAF) for a... more
BUILD-IT is a planning tool based on computer vision technology, supporting complex planning and composition tasks. A group of people, seated around a table, interact with objects in a virtual scene using real bricks. A plan view of the... more
As early as 15 years ago, it was claimed that organizational intervention research lacks consensus about research methods and theory and that more systematic efforts are needed to overcome this theoretical-methodological gap in knowledge.... more
The present paper develops a multi–dimensional genetic algorithm for the Resource constrained project scheduling problem. This algorithm performs a series of perturbations in an attempt to improve the current solution, applying some... more