Papers by Nopphadol Chalortham
2008 5th International Conference on Electrical Engineering/Electronics, Computer, Telecommunications and Information Technology, 2008
In this paper, we propose a design of tablet production ontology to support a generic drug tablet... more In this paper, we propose a design of tablet production ontology to support a generic drug tablet production expert system. The ontology is used to model the information about pharmaceutical tablet production that consists of a list of ingredients and their quantity, a set of tablet manufacturing instructions in laboratory scale, drugindependent standard quality controls that follow USP requirements, and drug-dependent equivalent quality controls such as dissolution profile and disintegration time. The tablet production ontology can also be reused and extended to support other pharmaceutical dosage forms production such as capsule, cream, gel and injection.
An expert system for tablet production of herbal and generic drug /
Ontology Development for Type II Diabetes Mellitus Clinical Support System
Diabetes mellitus becomes a serious problem in most countries. A continuous plan and management f... more Diabetes mellitus becomes a serious problem in most countries. A continuous plan and management for DM patients to control the blood glucose level and to monitor progress of DM’s complications becomes an important issue. We proposed an ontology-based development for clinical information system which enables health providers who are non-experts in Diabetes disease can suggest patients the essential activities for improving life quality and achieving goals of DM treatment. In this paper, we mainly focus on the ontology development process for Type II DM. There are three main steps, 1) domain and scope setting, 2) important terms acquisition, classes and class hierarchy conceptualization and 3) instances instantiation. We show an example of using reminding system which it developed based on our ontology.

An Ontology-based Framework for Development of Clinical Reminder System to Support Chronic Disease Healthcare
Improving quality of healthcare for people with chronic conditions requires informed and knowledg... more Improving quality of healthcare for people with chronic conditions requires informed and knowledgeable healthcare providers and patients. Decision support and clinical information system are two of the main components to support improving chronic care. In this paper, we describe an ontologybased information and knowledge management framework that is important for chronic disease care management. Ontologybased knowledge acquisition and modeling based on knowledge engineering approach provides an effective mechanism in capturing expert opinion in form of clinical practice guidelines. The framework focuses on building of healthcare ontology and clinical reminder system that link clinical guideline knowledge with patient registries to support evidenced-based healthcare. We discuss approaches in integrating clinical reminder services to existing healthcare provider environment by focusing on augmenting decision making and improving quality of patient care services.
Diabetes mellitus becomes a serious problem in most countries. A conti-nuous plan and management ... more Diabetes mellitus becomes a serious problem in most countries. A conti-nuous plan and management for DM patients to control the blood glucose level and to monitor progress of DM's complications becomes an important issue. We proposed an ontology-based development for clinical information system which enables health providers who are non-experts in Diabetes disease can suggest patients the essential activi-ties for improving life quality and achieving goals of DM treatment. In this paper, we mainly focus on the ontology development process for Type II DM. There are three main steps, 1) domain and scope setting, 2) important terms acquisition, classes and class hierarchy conceptualization and 3) instances in-stantiation. We show an example of using reminding system which it de-veloped based on our ontology.

Communications in Computer and Information Science, 2009
Improving quality of healthcare for people with chronic conditions requires informed and knowledg... more Improving quality of healthcare for people with chronic conditions requires informed and knowledgeable healthcare providers and patients. Decision support and clinical information system are two of the main components to support improving chronic care. In this paper, we describe an ongoing initiative that emphasizes the need for healthcare knowledge management to support both components. Ontology-based knowledge acquisition and modeling based on knowledge engineering approach provides an effective mechanism in capturing expert opinion in form of clinical practice guidelines. The Semantic Web framework is adopted in building a knowledge management platform that allows integration between the knowledge with patient databases and supported publications. We discuss one of the challenges, which is to apply the healthcare knowledge into existing healthcare provider environments by focusing on augmenting decision making and improving quality of patient care services.
OXPIRT: Ontology-based eXpert system for Production of a generic Immediate Release Tablet
Formulation Tools for Pharmaceutical Development, 2013

2011 7th International Conference on Natural Language Processing and Knowledge Engineering, 2011
The spreading of thalassemia, the most common genetic disease in tropical areas, is increasing du... more The spreading of thalassemia, the most common genetic disease in tropical areas, is increasing due to a migration thus the prevention and control program (PCP) of Thalassemia has been established. To better promote the yet unsuccessful PCP for thalassemia, ontology called PCPThalOnto is developed. The proposed ontology represents domain knowledge while a list of executable production rule is generated to represent operational knowledge. The PCPThalOnto consists of 1) class component to represent concepts of strategies, methodologies, techniques and activities of the PCP and 2) relation component to link between those classes or class and its instance. In the production rules, conditions for individual case determination are employed to execute a proper action. The well-constructed knowledge representation of PCP for thalassemia is developed as an electronic knowledge base for future applications to efficiently disseminate the underlying knowledge to people bridging the gap that deter the success of PCP.
A Framework of Ontology-Based Tablet Production Supporting System for a Drug Reformulation
IEICE Transactions on Information and Systems, 2011
A Framework of Ontology-Based Tablet Production Supporting System for a Drug Reformulation
IEICE Transactions on Information and Systems, 2011
2008 5th International Conference on Electrical Engineering/Electronics, Computer, Telecommunications and Information Technology, 2008
In this paper, we propose a tablet production ontology to support a generic drug tablet productio... more In this paper, we propose a tablet production ontology to support a generic drug tablet production expert system. The ontology is used to model the information about pharmaceutical tablet production that consist of a list of ingredients and its quantity, a set of instructions that explain how to manufacture tablet in laboratory scale, standard quality control that follow USP requirements, and equivalent quality controls (dissolution profile and disintegration time). It can reusable and sharable with others pharmaceutical dosage forms production such as capsule, cream, gel and injection.
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Papers by Nopphadol Chalortham