Papers by Nguyễn Thành Huy
Association of Self-Reported Allergic Rhinitis with Dengue Severity: A Case-Control Study
Social Science Research Network, 2022
Vietnam Journal of Hydrometeorology
Association of self-reported allergic rhinitis with dengue severity: A case-control study
Acta Tropica
BMC Medical Education
Background Students face hardships in determining what are the main points that need more studyin... more Background Students face hardships in determining what are the main points that need more studying in every subject. Checklists are one of the ways that can help students identify the most important pieces of information. Accordingly, in this study, we aimed at examining the impact of using educational checklists on the learning process of postgraduate students at Nagasaki University, Japan. Methods Thirty-one Master's students, who finished a “how to write a research protocol” course were recruited by sending them an invitation email that had an attached link to a previously developed and tested questionnaire on the SurveyMonkey® platform. After signing the electronic informed consent, twenty-two participants (response rate = 71%) finished the survey. The data was analyzed using Microsoft Excel and expressed in the form of frequencies and percentages. Results More than half of the students declared that they know the checklist will be used in the course that we investigated. On...
Frontiers in Public Health
Journal of 108 - Clinical Medicine and Phamarcy, 2022
Mục tiêu: Đánh giá hiệu quả của thông khí áp lực dương không xâm nhập có hỗ trợ áp lực (BiPAP) tr... more Mục tiêu: Đánh giá hiệu quả của thông khí áp lực dương không xâm nhập có hỗ trợ áp lực (BiPAP) trên bệnh nhân suy hô hấp cấp do suy tim cấp mất bù. Đối tượng và phương pháp: Nghiên cứu mô tả 39 bệnh nhân suy hô hấp cấp do suy tim cấp mất bù không đáp ứng với điều trị nội khoa tiêu chuẩn được hỗ trợ hô hấp bằng thông khí áp lực dương không xâm nhập tại Khoa Hồi sức tim mạch, Bệnh viện Trung ương Quân đội 108 từ tháng 6/2020 đến tháng 11/2020. Kết quả: Trong 39 bệnh nhân được thông khí áp lực dương không xâm nhập, có 3 bệnh nhân phải chuyển đặt ống nội khí quản thở máy xâm nhập (7,7%), thời gian thở máy không xâm trung bình là 153,46 ± 47,16 phút, thời gian nằm viện trung bình 10,51 ± 6,03 ngày. Các thông số lâm sàng và khí máu cải thiện có ý nghĩa thống kê ngay trong giờ đầu. Biến chứng do thông khí áp lực dương không xâm nhập: Tổn thương da mặt, khô mắt (23,1%), trào ngược dạ dày - thực quản (12,8%), viêm phổi (7,7%), tụt huyết áp (7,7%). Thời gian thở máy không xâm nhập có mối tươn...
A Safe and Energy-Efficient Location Update Algorithm for Smartphone-based Intersection Pedestrian Assistance Applications
Journal of Cardiovascular Medicine, 2019
The aim of the study was to determine the association between pet ownership and cardiovascular ri... more The aim of the study was to determine the association between pet ownership and cardiovascular risk factors and mortality. Electronic search was conducted through nine databases including PubMed for relevant publications reporting cardiovascular events and mortality among pet owners. Meta-analysis was used to pool the results. Of a total of 2818 reports screened, 26 studies were included in our systematic review and meta-analysis. Higher survival rate was observed in the pet owners group after pooling nonadjusted and adjusted hazard ratios for cardiovascular mortality at 0.73 [95% confidence interval (CI) 0.62–0.86] and 0.81 (0.68–0.97), respectively. A similar trend was observed for the pooled nonadjusted hazard ratio for overall mortality 0.73 (0.62–0.87) but not the adjusted hazard ratio 0.40 (0.04–3.78). Cat owners have a reduction in cardiovascular mortality but not overall mortality after pooling the adjusted hazard ratio 0.79 (0.63–0.99) and 1.04 (0.90–1.21), respectively. Ho...
Reviews in Medical Virology, 2019
SummaryImported dengue cases are thought to be important source for transmission of autochthonous... more SummaryImported dengue cases are thought to be important source for transmission of autochthonous dengue in Europe. We aimed to investigate the prevalence of dengue in Europe, its severity, and factors associated with it. Out of 5287 reports resulting from the search of nine electronic search engines, we included 174 reports. Meta‐analysis was performed by pooling the event rate and 95% confidence interval (CI). Subgroup meta‐analyses were performed to test the effect of the covariates. Among 20 284 reported cases, 130 autochthonous dengue cases were reported in eight countries with the highest number of cases reported in Israel (n = 41). The highest number of imported dengue cases was in Germany (n = 6638) then France (n = 6610). Most cases were imported from Southeast Asia (n = 2533) especially Thailand. Dengue infection cases increased with time, with 4157 cases reported in 2010. Second dengue infection and dengue serotype 2 were positively associated with dengue severity. The pr...
Virologica Sinica, 2019
The spelling of the fifth author's name was misspelled. The byline should appear as shown above. ... more The spelling of the fifth author's name was misspelled. The byline should appear as shown above. The original article has been corrected.
Reviews in Medical Virology, 2019
SummaryThere is a need for improved treatment of patients with chronic hepatitis B (CHB). We revi... more SummaryThere is a need for improved treatment of patients with chronic hepatitis B (CHB). We reviewed the literature to explore the efficacy of HB vaccines alone or in combination therapy (CT) with antiviral drugs in CHB patients and to meta‐analyze data from randomized controlled trials. We conducted a systematic search in ten databases. All studies investigating the efficacy of HBV vaccine in HBV infected patients were included with no restrictions. Among 1359 studies initially identified, 23 studies (n = 1956 patients) were included for the final analysis. CT showed a significant reduction of HBV DNA compared with analogue monotherapy (AM) at the 12‐month follow‐up period (odds ratio (OR) = 2.835, 95% confidence interval (CI) [1.275, 6.306], p = .011). Additionally, CT also remarkably induce HbsAg loss in comparison with AM (OR = 11.736, 95% CI [1.841, 74.794], p = .009). Our pooled data revealed no difference between treatment and control regarding alanine aminotransferase norma...
Reviews in Medical Virology, 2019
Background: Degranulation of mast cells (MCs) releases several mediators such as vascular endothe... more Background: Degranulation of mast cells (MCs) releases several mediators such as vascular endothelial growth factor (VEGF), chymase, tryptase, histamine, and cytokines, which all have important roles in the severity of dengue infection. We aimed to investigate the role of MCs in severity of dengue. Methods: We searched for relevant studies in 10 databases on 15 August 2016. Meta-analysis (MA) was conducted by R version 3.5.0. Results: We included 24 studies. in vivo and in vitro studies showed higher MC products released from infected mice/cells with dengue virus. In addition, when administering MC stabilizers or antihistaminic drugs, there was a decrease in vascular/ capillary permeability. In human and at early stages, studies revealed an insignificant difference in VEGF levels in dengue fever (DF) versus dengue hemorrhagic fever Nourin Ali Sherif and Ahmad Helmy Zayan equally contributed to this work.
Virologica Sinica, 2019
Provide a structured summary including, as applicable: background; objectives; data sources; stud... more Provide a structured summary including, as applicable: background; objectives; data sources; study eligibility criteria, participants, and interventions; study appraisal and synthesis methods; results; limitations; conclusions and implications of key findings; systematic review registration number.
Brazilian Journal of Otorhinolaryngology, 2019
Introduction: Nasal obstruction is one of the most frequent otolaryngologic complaints; and the c... more Introduction: Nasal obstruction is one of the most frequent otolaryngologic complaints; and the collapse of the internal nasal valve is one the main causes of the nasal air flow obstruction. Objective: We aimed to evaluate internal nasal valve by using reformatted CT-scans pre-and postrhinoplasty at 3 months and to assess its correlation to symptomatic improvement of nasal obstruction using the NOSE scale. Methods: A prospective observational study was conducted between March 2017-May 2018 in a tertiary care otorhinolaryngology center. We included patients suffering from nasal obstruction secondary to internal nasal angle collapse and nasal deformity. Patients with sinusitis, nasal polyposis, and nasal masses were excluded. Results: Twenty consecutive patients underwent rhinoplasty, with a mean age (22.2 ± 2.8), with majority of males (n = 14; 70%). There was no significant correlation between pre-and post-CTscans of the internal nasal valve angle/area and NOSE scores. A high significant difference was detected between mean pre-and post-NOSE scores (p < 0.0001), which was absent in CT-scan results.
Chemical Biology & Drug Design, 2019
Losing weight has significant impact on chronic disease management. Orlistat, a lipase inhibitor,... more Losing weight has significant impact on chronic disease management. Orlistat, a lipase inhibitor, has alternative effect for weight controlling. To find more candidates, we conducted a review of chalcone and xanthine derivatives regarding their anti-lipase activity. Eight databases were searched including PubMed, Scopus, Web of Science (ISI), Virtual Health Library (VHL), System for Information on Grey Literature in Europe (SIGLE), Global Health Library (GHL), EMBASE, and Google Scholar in August 2018. We found chalcone scaffold was more effective on lipase inhibition than xanthine scaffold. Among 19 investigated chalcones, only isoliquiritigenin and licuroside demonstrated an effect on preventing weight-gain and increase of in total cholesterol and total triglycerides aside apart from their high activity on inhibiting lipase. Effect and type of inhibition of individual chalcones differed depending on their structure. In addition, very few studies investigated xanthine compounds and their activities were inconsistent. We suggest more studies investigate the ability of chalcones and modifying their structure find out other compounds with higher efficacy.
Phytotherapy Research, 2019
This systematic review and meta‐analysis aimed to study the efficacy and safety of chamomile for ... more This systematic review and meta‐analysis aimed to study the efficacy and safety of chamomile for the treatment of state anxiety, generalized anxiety disorders (GADs), sleep quality, and insomnia in human. Eleven databases including PubMed, Science Direct, Cochrane Central, and Scopus were searched to retrieve relevant randomized control trials (RCTs), and 12 RCTs were included. Random effect meta‐analysis was performed by meta package of R statistical software version 3.4.3 and RevMan version 5.3. Our meta‐analysis of three RCTs did not show any difference in case of anxiety (standardized mean difference = −0.15, 95% CI [−0.46, 0.16], P = 0.4214). Moreover, there is only one RCT that evaluated the effect of chamomile on insomnia and it found no significant change in insomnia severity index (P > 0.05). By using HAM‐A scale, there was a significant improvement in GAD after 2 and 4 weeks of treatment (mean difference = −1.43, 95% CI [−2.47, −0.39], P = 0.007), (MD = −1.79, 95% CI [−...
Journal of Evaluation in Clinical Practice, 2019
AimDiuretics are a cornerstone in treatment of heart failure (HF). Torasemide is a loop diuretic ... more AimDiuretics are a cornerstone in treatment of heart failure (HF). Torasemide is a loop diuretic with a potential advantage over other diuretics. We aim to meta‐analyse and compare the effect of torasemide with furosemide in HF patients.MethodsA comprehensive literature search using 12 databases including PubMed, Scopus, and Web of Science was performed. All randomized controlled trials (RCTs) comparing furosemide and torasemide in HF patients were included and meta‐analysed. We assessed the risk of bias using Cochrane Collaboration's tool. The protocol was registered in PROSPERO (CRD42016046112).ResultsEighteen RCTs with 1598 patients were included. There was a significant difference between torasemide 20 mg and furosemide 40 mg in increasing the urine volume (standard difference of the mean (SDM) [95% confidence interval] = −0.78 [−1.52 to −0.053], P = .036). Torasemide 10 mg and 10 to 20 mg have a significant effect on potassium excretion in comparison with furosemide 25 to 4...
Pediatrics & Neonatology, 2019
Background: Newborns commonly experience pain due to a variety of reasons. Non-nutritive sucking ... more Background: Newborns commonly experience pain due to a variety of reasons. Non-nutritive sucking (NNS) is thought to be an effective non-pharmacological method of pain-relief. However, the significant heterogeneity in some systematic reviews limited the certainty of the findings about NNS. Hence, this study was aimed at evaluating the analgesic effect and safety of NNS in healthy term neonates during the heel prick test, using the Neonatal Pain Agitation and Sedation Scale (N-PASS). Methods: In this randomized controlled trial, 42 term infants were included: 22 infants in the intervention group (receiving NNS) and 20 infants in the control group (not receiving NNS). In the intervention group, neonates were given a silicone pacifier 120 s before, during, and 120 s after the heel puncture, while neonates in the control group received routine care. Painrelated outcomes were assessed using the N-PASS at 30s, 60s, 90s, and 120s after the heel prick. Any adverse events during the procedure were noted. The Spearman correlation
Tropical Medicine and Health, 2019
Background: The massive abundance of studies relating to tropical medicine and health has increas... more Background: The massive abundance of studies relating to tropical medicine and health has increased strikingly over the last few decades. In the field of tropical medicine and health, a well-conducted systematic review and meta-analysis (SR/MA) is considered a feasible solution for keeping clinicians abreast of current evidence-based medicine. Understanding of SR/MA steps is of paramount importance for its conduction. It is not easy to be done as there are obstacles that could face the researcher. To solve those hindrances, this methodology study aimed to provide a step-by-step approach mainly for beginners and junior researchers, in the field of tropical medicine and other health care fields, on how to properly conduct a SR/MA, in which all the steps here depicts our experience and expertise combined with the already well-known and accepted international guidance. We suggest that all steps of SR/MA should be done independently by 2-3 reviewers' discussion, to ensure data quality and accuracy. Conclusion: SR/MA steps include the development of research question, forming criteria, search strategy, searching databases, protocol registration, title, abstract, full-text screening, manual searching, extracting data, quality assessment, data checking, statistical analysis, double data checking, and manuscript writing.
BMC Medical Research Methodology, 2019
Background: The quality of systematic reviews and meta-analyses (SR/MAs) depends on the extent of... more Background: The quality of systematic reviews and meta-analyses (SR/MAs) depends on the extent of the methods used. We investigated the methodological steps used by authors of SR/MAs of clinical trials via an author survey. Methods: We conducted an email-based cross-sectional study by contacting corresponding authors of SR/MAs that were published in 2015 and 2016 and retrieved through the PubMed database. The 27-item questionnaire was developed to study the methodological steps used by authors when conducting a SR/MA and the demographic characteristics of the respondent. Besides the demographic characteristics, methodological questions regarding the source, extraction and synthesis of data were included. Results: From 10,292 emails sent, 384 authors responded and were included in the final analysis. Manual searches were carried out by 69.2% of authors, while 87.3% do updated searches, 49.2% search grey literature, 74.9% use the Cochrane tool for risk of bias assessment, 69.8% assign more than two reviewers for data extraction, 20.5% use digital software to extract data from graphs, 57.9% use raw data in the meta-analysis, and 43.8% meta-analyze both adjusted and non-adjusted data. There was a positive correlation of years of experience in conducting of SR/MAs with both searching grey literature (P = 0.0003) and use of adjusted and non-adjusted data (P = 0.006). Conclusions: Many authors still do not carry out many of the vital methodological steps to be taken when performing any SR/MA. The experience of the authors in SR/MAs is highly correlated with use of the recommended tips for SR/MA conduct. The optimal methodological approach for researchers conducting a SR/MA should be standardized.
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Papers by Nguyễn Thành Huy