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All Journal Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) As-syifaa Jurnal Farmasi Window of Health : Jurnal Kesehatan UMI Medical Journal ad-Dawaa : Journal of Pharmaceutical Sciences Jurnal Mandala Pengabdian Masyarakat Jurnal Kajian Ilmu Manajamen Journal of Global Pharma Technology Journal Microbiology Science Jurnal Indonesia : Manajemen Informatika dan Komunikasi Jurnal Pengabdian Masyarakat Journal of Pharmaceuticals and Natural Sciences KOPEMAS MPSJ Jurnal Ilmiah Nusantara

Rizqi Nur Azizah

Fakultas Farmasi Universitas Muslim Indonesia

Author-ID : 2645073

Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Uji Nefroterapi Ekstrak Etanol Daun Afrika (Vernonia amygdalina Delile) Dengan Parameter Ureum Tikus Putih Jantan yang Diinduksi Gentamisin Azizah, Rizqi Nur; Santi, Irma; Marlian, Ayu
Window of Health : Jurnal Kesehatan Vol. 2 No. 2 (April, 2019)
Publisher : Fakultas Kesehatan Masyarakat Universitas Muslim Indonesia

African leaves (Vernonia amygdalina Delile.) contain flavonoids having an antioxidant activities. The research aimed to determine the nephrotherapy effect of the ethanolic extract of African leaves with the parameter of male rat urea (Rattus norvegicus) induced by gentamicin. The research used 18 rats divided into 6 groups consisting of group I as the normal group, group Il the Negative Control (gentamicin 80 mg I kgBW), group Ill the Positive Contfol (amino acid supplement), group IV, V, and VI given the ethanol extract of African leaves, each dose of 100 mg/kgBW, 250 mg/kgBW, 500 mg/kgBW. The induction of gentamicin 80 mg/kg BW was administered for eight days and the therapy for the ethanol extract of African leaves for fourteen days. The research data were statistically analyzed using the ANOVA test followed by the Post Hoc LSD test. The results showed that the ethanol extract of African leaves had the nephrotherapy effects in reducing the urea in male rat induced by gentamicin.

PKM Socialization and Education on the Utilization of Medicinal Efficacious Plants in Tamangapa Village, Ma'rang District, Pangkep Regency Rizqi Nur Azizah; Rahmawati Rahmawati; Aulia Wati
Jurnal Mandala Pengabdian Masyarakat Vol. 2 No. 2 (2021): Jurnal Mandala Pengabdian Masyarakat
Publisher : Progran Studi Farmasi STIKES Mandala Waluya

Salah satu upaya efektif dalam mencegah penyebaran COVID-19 ialah dengan cara meningkatkan daya tahan tubuh. Bentuk kesadaran masyarakat dalam mencegah dan melawan virus COVID-19 salah satunya adalah dengan memanfaatkan tanaman berkhasiat obat yang dapat meningkatkan sistem imunitas tubuh. Tamangapa adalah salah satu desa di kecamatan Ma’rang kabupaten Pangkep yang merupakan desa binaan Universitas Muslim Indonesia (UMI). Kegiatan pengabdian ini berupa penyuluhan dengan metode ceramah dan tanya jawab yang bertujuan membantu pemerintah setempat dalam meningkatkan kesadaran masyarakat untuk mencegah dan melawan virus COVID-19 dalam bentuk pemanfaatan tanaman berkhasiat obat yang dapat meningkatkan sistem imunitas tubuh. Luaran yang dihasilkan adalah adanya peningkatan pemahaman masyarakat khususnya Ibu-ibu Majelis Taklim Nurul Iman Desa Tamangapa terkait tanaman obat yang dapat meningkatkan sistem imun serta tersedianya Pocket Book “Obat Tradisional untuk Sistem Imun”.

UJI EFEK DIURETIK INFUS BIJI JAGUNG (Zea Mays L), RAMBUT JAGUNG DAN KOMBINASI ANTARA KEDUANYA PADA KELINCI JANTAN (Oryctolagus Cuniculus) BERDASARKAN PARAMETER FREKUENSI URINASI DAN VOLUME URIN Hendra Herman; Rizqi Nur Azizah; Chikita Inaku
As-Syifaa Jurnal Farmasi Vol 4, No 1 (2012): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Has been done research Diuretic effect test of seed corn infusem, hair Corn infuse and combination of both in order to determining diuretic effect with frequency urination and volume urine parameters. This research use trial animals as many as 15 male rabbits, divided into 5 groups and each group consisted of three tails, group I is control that given colloidal solution of Na.CMC 1 %, group II infuse corn (Zea mays L) 23 33 mg group III has Qvien seed corn infuse (Zee mays L ) 466,664 gr, group IV has Given combination of hair and sedd corn infuse and group V is comparator that given suspension of furosemid Treatment done orally with a dose of 20 / 2,5 kg for further observation and measurement frequency done diuretic and urine volume intervals of 1 hour for 5 hours after treatment The result showed that infuse of seed corn, hair corn and combination of both can increase the frequency of urination, and just infuse of seed corn and hair corn increase the volume win of rabbits This is supported by statistical analysis methods CRD (Completely Randomized Design) For the frequency of urination infuse of seed corn, hair corn, and combination of both did not significantly different with furecemid while for the volume urine hair corn infuse and seed corn infuse are significantly different with Na CMC and not significantly different with furosemidKey words: Diuretic, seed and hair corn Infuse

IDENTIFIKASI PENGGUNAAN OBAT PADA PASIEN DIABETES MELLITUS TIPE II USIA LANJUT DENGAN BEER’S CRITERIA DI INSTALASI RAWAT INAP RUMAH SAKIT IBNU SINA MAKASSAR PERIODE TAHUN 2012 Rizqi Nur Azizah; A. Hudayah
As-Syifaa Jurnal Farmasi Vol 8, No 1 (2016): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Using identification in the use medicine with Beer's Criteria to the advanced age patients in Inpatient installation in Ibnu Sina Makassar Hospital which aims to observe, report, and identify in the use medicine in elderly patient of Type II Diabetes Mellitus are covered by Beer's Criteria in inpatient installation in Ibnu Sina Makassar Hospital period 2012. This is a descriptive research by collecting data retrospectively. The results of this research concluded in the use medicine there are 8 types of drugs covered by the Beer’s Criteria, they are alprazolam 14.28%, insulin 64.28%, gliburide (gluconic®) 1.19%, metoclopramide (sotatic®) 4.76%, Kal. Diklofenak (kataflam®) 1.19%, mefenamic acid 3.57%, meloxicam 2.38%, and ketorolak 8.33%.

UJI AKTIVITAS HIPOLIPIDEMIK EKSTRAK ETANOL HERBA KROKOT (Portulaca oleracea L.) PADA TIKUS OBESITAS DENGAN PARAMETER TRIGLISERIDA Rizqi Nur Azizah; Bayu Putra; Rafika Tobis
As-Syifaa Jurnal Farmasi Vol 10, No 1 (2018): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Hypolipidemics a drug used to lower plasma lipid levels in the blood. This study aimed to examine the hypolipidemic activity of ethanol extract of purslane herb (Portulaca oleracea L.) against the triglyceride level reduction in obese mice. The purslane herb contains omega-3, flavonoids and hight ascorbic acid as a lowering of triglyceride levels in the blood. This study used 15 malerats divided into 5 groups. Group I (negative control) was given Na.CMC 1%, group II (positive control) was given Gemfibrozil, group III, IV, and V were given ethanol extract of purslane herb with dose of 100 mg/kgBW, 200mg/kgBW, and 300 mg/kgBW as therapy group. All the administration were done orally once a day for 16 days. The measurement of triglyceride level was performed on early triglycerides before induction, after induction and after therapy. Before therapy, the rats were given hight-calorie diet. The results showed that the ethanol extract of purslanes herb has activity as hypolipidemic in lowering trygliseride level in obese mice. From the statistic result of One-Way ANOVA followed by LSD test, it can be concluded that the ethanol extract of purslane herb of the dose 100 mg/kgBW provide the most effective hypolipidemic activity that triglyceride level is not significantly different from positive control group (p>0,05).

PENENTUAN DOSIS MINIMUM EKSTRAK ETANOL HERBA KROKOT (Portulaca oleracea L.) TERHADAP PENURUNAN KADAR TRIGLISERIDA PADA TIKUS OBESITAS Irma Santi; Rizqi Nur Azizah; Mu’ammar Mu’ammar
As-Syifaa Jurnal Farmasi Vol 10, No 2 (2018): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Common purslane (Portulace Oleracea L.) has a compound of omega-3, flavonoid and ascorbic acid with the activity in decreasing triglyceride levels. This study aimed to determine the minimum dose of ethanol extract of common purslane against the decrease of triglyceride levels of obese mice. It used 18 rats fed high-calorie diet (HCD) for 30 days. The obese rats were devided into 6 groups consisting of group I of negative controls (Na.CMC ), group II of positive control (gemfibrozil®), group III,IV,V,VI provided the ethanol extract of common purslane (EECP) with 25 mg/kgBW, 50 mg/kgBW, 75 mg/kgBW, 100 mg/kgBW. Afterwards, 14 days of therapy were given and still fed a high-calorie (HCD). The measurement of triglyceride levels is performed before induction (early). After induction , and after therapy. The data of the study were analized by percentage decrease of each test group. The result show that the EECP groups of 75 mg/kgBW was the minimum dose in lowering triglyceride levels with a decrease of 16,49 %.

APLIKASI KOMPUTASI KIMIA DALAM ANALISIS HUBUNGAN KUANTITATIF STRUKTUR-AKTIVITAS (HKSA) DARI SENYAWA AKTIF ANTIBAKTERI ANALOG N-ALKIL IMIDAZOL PADA BAKTERI (Staphilococcus aureus) DENGAN PARAMETER ELEKTRONIKMETODE AUSTIN MODEL (AM 1) Rizqi Nur Azizah; Gemini Alam; Yusnita Rifai; Christiana Lethe
As-Syifaa Jurnal Farmasi Vol 5, No 1 (2013): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

A quantitative structure activity relationship study on a series of N-alkyl imidazole analogues using combination of various atomic descriptors and molecular descriptors have been investigated. The research was aimed to obtain mathematic equation Quantitative Structure-Activity Relationship of N-alkyl Imidazole analougues as antibacterial agents at bacteria Staphilococcus aureus with electronic parameters used semiempiric Austin Model 1 (AM1) method .Several statistical expressions were developed using stepwise multiple liner regression analysis. The best quantitative structure activity relationship models were further validated by leave-one-out method of cross-validation. The study revealed that the atomic net charges of C2&C3,E-Homo,E-lumo,dipole moment (µ),and Total Energy (ET) contributed positively, and atomic net charges of C1,N1,&N2,Binding Energy (Eb),RMS Gradient (RMS), and Elecrtonic Energy (Ee) contributed negatively. The quantitative structure activity relationship study provides important structural insights in designing of potent antibacterial agents. Several alternative models which have possibility to express the correlation betwen biological activity and electronic parameters, ”The best model” is represented by a linear function of activity versus atomic net charges of C2&C3 and E-Homo,E-lumo,dipole moment (µ),and Total Energy (Ee) is axpressed by:Log(1/C) = 114,614 (±28,461) + 505,362 (±149,739) qC2 + 247,641(±47,025)qC3 + 0,819(±0,379) E-Homo + 93,404 (±25,997)E-Lumo + -24,982(±6,066)µ + -0,002(±0,000).ET The cross validation analisys give minimal value of PRESS = 106,231and SEP = 3,435Key Words : QSAR, antibacterial, n-alkyl imidazole, Cross Validation Methods

Efek Nefroterapi Ekstrak Etanol Daun Afrika (Vernonia Amygdalina Delile) Parameter Kreatinin Tikus Putih Jantan Terinduksi Gentamisin Rizqi Nur Azizah
UMI Medical Journal Vol 4 No 1 (2019): June 2019
Publisher : Fakultas Kedokteran Universitas Muslim Indonesia

Nefroterapi adalah tindakan berupa pengobatan untuk memperbaiki kerja dari fungsi ginjal yang telah rusak. Kerusakan ginjal dapat disebabkan oleh obat-obat yang bersifat nefrotoksik seperti gentamisin. Keadaan ginjal yang mengalami kerusakan akan sulit dalam menseksresi produk sisa seperti kreatinin. Penelitian ini bertujuan untuk menentukan efek nefroterapi ekstrak etanol daun afrika (Vernonia amygdalina Delile) dengan parameter kreatinin tikus putih jantan yang terinduksi gentamisin. Penelitian ini menggunakan 18 ekor tikus putih yang dibagi ke dalam 6 kelompok. Semua kelompok diinduksi gentamisin dosis 80 mg/kgBB selama 8 hari secara i.p kecuali kelompok normal dan dilanjutkan dengan terapi selama 14 hari secara oral. Pengukuran kadar kreatinin dilakukan pada hari ke-0, 9 dan 23. Data hasil penelitian kemudian dianalisis secara statistika dengan menggunakan uji t-berpasangan, One Way-Anova dan dilanjutkan dengan uji LSD. Hasil analisa menunjukkan bahwa ekstrak etanol daun afrika dosis 100, 250 dan 500 mg/kgBB memiliki efek nefroterapi yang sama seperti suplemen asam amino (p>0,05).

Potensi Ekstrak Etanol Daun Kelor (Moringa oleifera L.) dalam Menurunkan Kadar Asam Urat Tikus Putih Bayu Putra; Rizqi Nur Azizah; Andi Clara
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol 2 No 2 (2019)
Publisher : Universitas Islam Negeri Alauddin Makassar

Daun kelor (Moringa oleifera L.) memiliki potensi yang diduga dapat menurunkan kadar asam urat tikus putih (Rattus norvegicus). Penelitian ini bertujuan untuk menentukan dosis ekstrak etanol daun kelora yang dapat menurunkan kadar asam urat tikus putih. Penelitian ini menggunakan 15 ekor tikus putih yang dibagi menjadi 5 kelompok. Kelompok I sebagai kontrol negatif yang diberikan jus hati ayam dan kalium oksonat 250 mg/kgBB, kelompok II sebagai kontrol positif yang diberikan allopurinol 5 mg/kgBB, dan kelompok III, IV, dan V sebagai kelompok perlakuan yang diberikan ekstrak etanol daun kelor dengan dosis 70, 140, dan 280 mg/kgBB selama 7 hari. Berdasarkan pengukuran kadar asam urat akhir didapatkan ekstrak etanol daun kelor dapat menurunkan kadar asam urat tikus putih.

Efek Hipoglikemik Ekstrak Etanol Daun Kelor (Moringa oleifera L.) pada Tikus Putih (Rattus norvegicus) Jantan Rizqi Nur Azizah; Rachmat Kosman; Syarifah Khaerunnisa
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol 1 No 2 (2018)
Publisher : Universitas Islam Negeri Alauddin Makassar

Daun Kelor (Moringa oleifera L.) secara empiris digunakan oleh masyarakat sebagai antidiabetes. Penelitian ini bertujuan untuk menentukan pengaruh pemberian ekstrak etanol daun kelor terhadap penurunan kadar glukosa darah tikus putih. Penelitian ini menggunakan 15 ekor tikus jantan yang dibagi menjadi 5 kelompok. Kelompok I merupakan kontrol negatif yang diberikan larutan Na.CMC 1%. Kelompok II, III dan IV adalah kelompok perlakuan yang diberikan ekstrak etanol daun kelor, berurutan, 50, 100, dan 150 mg/Kg BB. Kelompok V merupakan kontrol positif diberikan suspensi glibenklamid®. Sebelum perlakuan tikus dipuasakan selama 18 jam kemudian diinduksi dengan aloksan 150 mg/KgBB. Pengukuran kadar glukosa dilakukan pada hari ke 1, ke 3, ke 5, ke 7 dan ke 9. Hasil penelitian yang dilakukan menunjukkan ekstrak etanol daun kelor dapat menurunkan kadar glukosa darah. Dosis 100 mg/Kg BB memberikan efek penurunan kadar glukosa yang optimal dibandingkan dengan dosis ekstrak lainnya.

Co-Authors , Faradiba A. Hudayah Abdul Malik Ahmad, Aktsar Roskiana Aisyah Alda, Alda Andi Clara Ardiansah Hasin Asni Hasanuddin Asriani Suhaenah Asrianto, La Ode Aulia Wati Awali, Muhammad Noer Bayu Putra Bayu Putra, Bayu Chikita Inaku Christiana Lethe Fadlina Chany Saputri Fitriana Fitriana Gemini Alam Hendra Herman Irma Santi Irma Santi, Irma Iskandar Zulkarnain Karyadi Marlian, Ayu Mirawati Mirawati Mudinillah, Adam Muhammad Irman Mu’ammar Mu’ammar Nirma Kurriwati, Nirma Nopriyanti, Eka Maryam Nur Annisyah Nurwahida Nurwahida Rachmat Kosman Rafika Tobis Rini Suwartika Kusumadiarti Ririn Ririn SALIM, MUH.AGUS Sukmawati Sukmawati Syarifah Khaerunnisa Ulupalu, Fadila Fauzia Mutmaina Yurniati Yusnita Rifai

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