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bowel movement

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lightbulbAbout this topic
Bowel movement refers to the process of expelling feces from the digestive tract through the rectum. It is a key indicator of gastrointestinal health and involves coordinated muscular contractions of the intestines and rectum, influenced by various physiological, dietary, and lifestyle factors.
lightbulbAbout this topic
Bowel movement refers to the process of expelling feces from the digestive tract through the rectum. It is a key indicator of gastrointestinal health and involves coordinated muscular contractions of the intestines and rectum, influenced by various physiological, dietary, and lifestyle factors.

Key research themes

1. How does enteric nervous system dysfunction contribute to bowel motility disorders and neurological disease associations?

This research theme investigates the role of the enteric nervous system (ENS) in regulating gastrointestinal motility and its dysfunction in bowel disorders such as constipation, with a focus on how ENS abnormalities also relate to neurological diseases. Understanding ENS pathophysiology is vital because it operates semi-autonomously to coordinate bowel movements, and its impairment, through structural or neurochemical changes, leads to motility disorders and may serve as a conduit for neurodegenerative disease spread.

Key finding: This comprehensive review reveals that the ENS contains more neurons than peripheral ganglia and spinal cord, manifesting integrative activity that controls gastrointestinal motility independently of the central nervous... Read more
Key finding: The study provides direct histopathological evidence for enteric nervous system abnormalities in patients with obstructed defecation refractory to treatment. Specifically, a significant reduction in enteric neurons was... Read more
Key finding: Through analysis of full-thickness surgical bowel biopsies from patients with severe motility disorders predominantly presenting with constipation, this study identified histopathological abnormalities including hypertrophy... Read more
Key finding: This work delineates the multifaceted mechanisms coordinating colonic motility, integrating intrinsic myogenic pacemaking by interstitial cells of Cajal with complex enteric neural circuits. It highlights how high resolution... Read more

2. What are the current clinical methods and challenges in assessing gastrointestinal and colonic transit relevant to bowel movement disorders?

This theme focuses on the clinical measurement techniques for gastrointestinal motility and transit, their methodological developments, diagnostic utility, and limitations in functional bowel disorders such as constipation. Accurately measuring GI transit is critical for diagnosis, targeted treatment, and understanding disease mechanisms. Challenges remain in standardizing methodology, correlating transit times with symptoms, and implementing advanced technologies in clinical settings.

Key finding: This review critically appraises existing clinical tests for assessing gastrointestinal motility from oropharynx to anorectum, including high-resolution manometry and scintigraphy. It underscores the importance of strict... Read more
Key finding: This consensus statement consolidates and harmonizes terminologies and definitions for colonic motor patterns across species and study modalities to standardize colonic motility research. The work critically evaluates... Read more
Key finding: The mini-review highlights existing and emerging techniques to measure colonic transit such as radiopaque markers, scintigraphy, and novel electromagnetic capsules. It emphasizes that while radiopaque markers remain an... Read more
Key finding: This experimental study in healthy women demonstrates that commonly used bowel function measures—stool weight, defecation frequency, dye transit time, and fiber intake—are significantly correlated with gastrointestinal... Read more
Key finding: This clinical study establishes standardized protocols for interpreting abdominal radiographs during bowel management weeks in patients with various bowel disorders, including constipation. It emphasizes the importance of... Read more

3. How do biomechanical properties and sensory mechanisms regulate normal and disordered defecation dynamics?

This theme explores the biomechanical and sensory underpinnings of defecation, focusing on novel analytic techniques to quantify forces, pressures, and neural sensory feedback during stool passage. Understanding these mechanophysiological aspects is critical for elucidating the etiology of defecatory disorders such as constipation and for developing improved diagnostic tools and therapeutic approaches that integrate motility with sensory processing in the anorectal region.

Key finding: Using a novel Fecobionics device equipped with pressure sensors, motion units, and impedance rings, this study provides detailed measurements of anorectal biomechanics during defecation in healthy subjects. It quantifies... Read more
Key finding: This critical review elucidates the complexity of gastrointestinal sensation and motility integration, emphasizing the roles of intrinsic enteric neurons and extrinsic afferents via vagal and spinal pathways in... Read more
Key finding: In a randomized controlled trial, the adjunctive use of spinal magnetic stimulation (SMS) with biofeedback training significantly improved bowel evacuation and symptom control in adults with functional constipation compared... Read more

All papers in bowel movement

This study evaluated the efficacy and safety of postoperative acupressure in the recovery of the gastrointestinal system (GIS) after caesarean section. A total of 160 primipara pregnant women delivered by caesarean section under spinal... more
Background. Iron suplement programs, as an approach to overcoming anemia, indicate positive impact although many studies have also noted varying levels of success or even a failure. The known and commonly acknowledged side effect of iron... more
Background. Iron suplement programs, as an approach to overcoming anemia, indicate positive impact although many studies have also noted varying levels of success or even a failure. The known and commonly acknowledged side effect of iron... more
Constipation marked by feces hard one, dry, and difficult issued. About 73.9% pregnant women experience constipation. Increase in the hormone progesterone for pregnant women resulted in drop motility gastrointestinal tract. Constipation... more
Constipation marked by feces hard one, dry, and difficult issued. About 73.9% pregnant women experience constipation. Increase in the hormone progesterone for pregnant women resulted in drop motility gastrointestinal tract. Constipation... more
Constipation marked by feces hard one, dry, and difficult issued. About 73.9% pregnant women experience constipation. Increase in the hormone progesterone for pregnant women resulted in drop motility gastrointestinal tract. Constipation... more
Constipation marked by feces hard one, dry, and difficult issued. About 73.9% pregnant women experience constipation. Increase in the hormone progesterone for pregnant women resulted in drop motility gastrointestinal tract. Constipation... more
Background. Iron suplement programs, as an approach to overcoming anemia, indicate positive impact although many studies have also noted varying levels of success or even a failure. The known and commonly acknowledged side effect of iron... more
Background. Iron suplement programs, as an approach to overcoming anemia, indicate positive impact although many studies have also noted varying levels of success or even a failure. The known and commonly acknowledged side effect of iron... more
Constipation marked by feces hard one, dry, and difficult issued. About 73.9% pregnant women experience constipation. Increase in the hormone progesterone for pregnant women resulted in drop motility gastrointestinal tract. Constipation... more
Lower Hb level in anemia is one of the health problems that sometimes occur in adolescent girls compared to males characterized by menstruation cycle and miscocundcut of eating behaviors. Reduction of learing concentration a nd reduction... more
Lower Hb level in anemia is one of the health problems that sometimes occur in adolescent girls compared to males characterized by menstruation cycle and miscocundcut of eating behaviors. Reduction of learing concentration a nd reduction... more
Background: Constipation and other symptoms of gastrointestinal discomfort, such as abdominal swelling, are common among healthy individuals and have a significant impact on quality of life. Despite the known contribution of gut... more
Background. Iron suplement programs, as an approach to overcoming anemia, indicate positive impact although many studies have also noted varying levels of success or even a failure. The known and commonly acknowledged side effect of iron... more
Background: Okinawa mozuku (Cladosiphon okamuranu) is a type of edible seaweed of the family Chordariaceae that typically contains the polysaccharide fucoidan as a functional ingredient. In Okinawa, raw mozuku is eaten as vinegared mozuku... more
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