Key research themes
1. How do active versus expectant management strategies affect maternal outcomes and postpartum hemorrhage risk in the third stage of labour?
This research area critically examines the comparative effectiveness of active management—using prophylactic uterotonics, controlled cord traction, and cord clamping timing—and expectant (physiological) management in the third stage of labour, focusing on reducing postpartum haemorrhage (PPH) and other maternal complications. Given the substantial maternal mortality associated with PPH globally, especially in low-resource settings, understanding optimal strategies tailored to risk profiles and birth settings is crucial for improving maternal outcomes.
2. What are the impacts of prolonged second stage of labour on maternal and perinatal outcomes, and how should management be optimized?
Prolonged second stage labour is linked to increased risks including operative delivery, maternal trauma, neonatal morbidity, and postpartum hemorrhage. Research focuses on quantifying adverse outcomes associated with extended durations, evaluating timing thresholds for intervention, and optimizing clinical guidelines to balance maternal-fetal risks with minimizing unnecessary cesarean or instrumental deliveries. This theme draws on retrospective cohorts, clinical audits, and evidence-based algorithms to refine labor management protocols.
3. How do specific interventions during the third stage of labour (e.g., placental cord drainage, pharmacological analgesia, skin-to-skin contact) influence the duration, maternal morbidity, and physiological processes?
Focused investigations target the effect of adjunct interventions on the third stage of labour’s course and safety profile. Studies investigate the efficacy and physiological mechanisms of practices such as placental cord drainage in shortening placental delivery, the impact of programmed labor analgesia versus epidural on labor timelines, and the role of immediate skin-to-skin contact and breastfeeding in optimizing uterine contractility and reducing PPH. Understanding these interventions advances clinical guidelines toward more physiologically compatible and patient-centered care.