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Materials and Methods
Data Extraction and Analysis
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Biology
Biotechnology

Current research in biotechnology: Exploring the biotech forefront

Profile image of Andy Wai Kan YeungAndy Wai Kan YeungProfile image of Atanas G AtanasovAtanas G Atanasov

2019, Current Research in Biotechnology

https://doi.org/10.1016/J.CRBIOT.2019.08.003
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7 pages

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Abstract

Biotechnology is an evolving research field that covers a broad range of topics. Here we aimed to evaluate the latest research literature, to identify prominent research themes, major contributors in terms of institutions, countries/re-gions, and journals. The Web of Science Core Collection online database was searched to retrieve biotechnology articles published since 2017. In total, 12,351 publications were identified and analyzed. Over 8500 institutions contributed to these biotechnology publications, with the top 5 most productive ones scattered over France, China, the United States of America, Spain, and Brazil. Over 140 countries/regions contributed to the biotechnology research literature, led by the United States of America, China, Germany, Brazil, and India. Journal of Bioscience and Bioengineer-ing was the most productive journal in terms of number of publications. Metabolic engineering was among the most prevalent biotechnology study themes, and Escherichia coli and Saccharomyces cerevisiae were frequently used in biotechnology investigations, including the biosynthesis of useful biomolecules, such as myo-inositol (vitamin B8), mono-terpenes, adipic acid, astaxanthin, and ethanol. Nanoparticles and nanotechnology were identified too as emerging biotechnology research themes of great significance. Biotechnology continues to evolve and will remain a major driver of societal innovation and development.

Figures (9)
Fig. 1. Publication count of different document types.
Fig. 1. Publication count of different document types.
The top 5 most productive institutions, countries/regions, and journals. Table 1
The top 5 most productive institutions, countries/regions, and journals. Table 1
The publication count and citation per publication of the top 20 most productive journal categories. Table 2
The publication count and citation per publication of the top 20 most productive journal categories. Table 2
Fig. 2. Term map of biotechnology publications. There were 411 terms that appeared in >1% (n = 124) of the 12,351 publications published in 2017-2019 (until May) and extracted from Web of Science. The bubble size reflects how frequently a term was mentioned in the included publications (multiple mentioning in one publication counted as one only). The bubble color reflects how frequently a publication mentioning the term was cited on average. The distance between two bubbles reflects how frequently two terms were mentioned in the same publications. Journal of Bioscience and Bioengineering stood out as the most productive journal, having contributed to 4.0% of all publications, more than double of the contribution by the 2nd journal (Biotechnology and Bioengineering; con- tributing 1.8%). This is different from other recently analyzed sets of liter- ature in which no single journal clearly outperformed the others, e.g., in the research fields of dietary natural products (Yeung et al., 2018a), curcumin (Yeung et al., 2019b), resveratrol (Yeung et al., 2019c), and neuropharma- cology (Yeung et al., 2018b). While the reasons for this observation are not entirely clear, it is apparent that Journal of Bioscience and Bioengineering (2018 journal impact factor of 2.03; publishing original full-length research papers, reviews, and Letters to the Editor) might currently represent a plat- form preferred by authors for publishing biotech-related articles (factors such as broadness of scope, diversity of article types, and acceptance rate can certainly be of importance in the context of this observation). In terms of journal category, we could also show that the dominating category was Biotechnology applied microbiology, having three-fold more contribu- tions compared to the 2"¢ category. On the other hand, by examining the top 20 categories, one could appreciate the diversity of biotechnology re- search, which overlapped with the areas of biology, chemistry, engineering, plant sciences, microbiology, pharmacology, genetics, nanoscience, and management (Table 2). This wide spectrum is illustrative for the highly in- terdisciplinary nature of biotechnology-linked research that expands be- yond the life sciences to cover scientific works from fields such as engineering or management. In management journals, for example, rele- vant publications often analyzed biotechnology cases to investigate how knowledge advancements and maturation could be adopted as product in- novations (Capaldo et al., 2017; Moeen and Agarwal, 2017). Along the same lines, biotech startup companies have become popular in recent years, propelled by collaborations between the industry and academia via contaminant chromium (Vendruscolo et al., 2017), and the use of microalgae and cyanobacteria to biofix carbon dioxide emitted from coal power plants (Duarte et al., 2017). Among the most cited Indian publica- tions, the oxidase laccase was one of the common themes. Notable exam- ples included a study that optimized the production of laccase from a fungus under solid state fermentation (Chenthamarakshan et al., 2017), and a demonstration of biodegradation of toxic textile dyes mediated by laccase produced by bacteria (Kuppusamy et al., 2017).
Fig. 2. Term map of biotechnology publications. There were 411 terms that appeared in >1% (n = 124) of the 12,351 publications published in 2017-2019 (until May) and extracted from Web of Science. The bubble size reflects how frequently a term was mentioned in the included publications (multiple mentioning in one publication counted as one only). The bubble color reflects how frequently a publication mentioning the term was cited on average. The distance between two bubbles reflects how frequently two terms were mentioned in the same publications. Journal of Bioscience and Bioengineering stood out as the most productive journal, having contributed to 4.0% of all publications, more than double of the contribution by the 2nd journal (Biotechnology and Bioengineering; con- tributing 1.8%). This is different from other recently analyzed sets of liter- ature in which no single journal clearly outperformed the others, e.g., in the research fields of dietary natural products (Yeung et al., 2018a), curcumin (Yeung et al., 2019b), resveratrol (Yeung et al., 2019c), and neuropharma- cology (Yeung et al., 2018b). While the reasons for this observation are not entirely clear, it is apparent that Journal of Bioscience and Bioengineering (2018 journal impact factor of 2.03; publishing original full-length research papers, reviews, and Letters to the Editor) might currently represent a plat- form preferred by authors for publishing biotech-related articles (factors such as broadness of scope, diversity of article types, and acceptance rate can certainly be of importance in the context of this observation). In terms of journal category, we could also show that the dominating category was Biotechnology applied microbiology, having three-fold more contribu- tions compared to the 2"¢ category. On the other hand, by examining the top 20 categories, one could appreciate the diversity of biotechnology re- search, which overlapped with the areas of biology, chemistry, engineering, plant sciences, microbiology, pharmacology, genetics, nanoscience, and management (Table 2). This wide spectrum is illustrative for the highly in- terdisciplinary nature of biotechnology-linked research that expands be- yond the life sciences to cover scientific works from fields such as engineering or management. In management journals, for example, rele- vant publications often analyzed biotechnology cases to investigate how knowledge advancements and maturation could be adopted as product in- novations (Capaldo et al., 2017; Moeen and Agarwal, 2017). Along the same lines, biotech startup companies have become popular in recent years, propelled by collaborations between the industry and academia via contaminant chromium (Vendruscolo et al., 2017), and the use of microalgae and cyanobacteria to biofix carbon dioxide emitted from coal power plants (Duarte et al., 2017). Among the most cited Indian publica- tions, the oxidase laccase was one of the common themes. Notable exam- ples included a study that optimized the production of laccase from a fungus under solid state fermentation (Chenthamarakshan et al., 2017), and a demonstration of biodegradation of toxic textile dyes mediated by laccase produced by bacteria (Kuppusamy et al., 2017).
The top 25 recurring terms from titles and abstracts. Table 3 Table 5
The top 25 recurring terms from titles and abstracts. Table 3 Table 5
The top 25 recurring keywords added by Web of Science (Keywords Plus).
The top 25 recurring keywords added by Web of Science (Keywords Plus).
The top 25 recurring author keywords. Table 4
The top 25 recurring author keywords. Table 4
Fig. 3. Structures of selected natural products with biotechnological relevance.
Fig. 3. Structures of selected natural products with biotechnological relevance.

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References (53)

  1. Adams, J., 2013. Collaborations: the fourth age of research. Nature 497, 557-560.
  2. Amarakoon, I., Hamilton, C., Mitchell, S., Tennant, P., Roye, M., 2017. Chapter 28 -biotech- nology. Pharmacognosy: Fundamentals, Applications and Strategies. Academic Press, pp. 549-563.
  3. Atanasov, A.G., Waltenberger, B., Pferschy-Wenzig, E.-M., Linder, T., Wawrosch, C., Uhrin, P., Temml, V., Wang, L., Schwaiger, S., Heiss, E.H., 2015. Discovery and resupply of pharma- cologically active plant-derived natural products: a review. Biotechnol. Adv. 33, 1582-1614.
  4. Fig. 3. Structures of selected natural products with biotechnological relevance.
  5. Barcelos, M.C., Lupki, F.B., Campolina, G.A., Nelson, D.L., Molina, G., 2018. The colors of bio- technology: general overview and developments of white, green and blue areas. FEMS Microbiol. Lett. 365, fny239.
  6. Beopoulos, A., Cescut, J., Haddouche, R., Uribelarrea, J.-L., Molina-Jouve, C., Nicaud, J.-M., 2009. Yarrowia lipolytica as a model for bio-oil production. Prog. Lipid Res. 48, 375-387.
  7. Brahmi, F., Vejux, A., Sghaier, R., Zarrouk, A., Nury, T., Meddeb, W., Rezig, L., Namsi, A., Sassi, K., Yammine, A., 2018. Prevention of 7-ketocholesterol-induced side effects by nat- ural compounds. Crit. Rev. Food Sci. Nutr. 1-20.
  8. Bud, R., 1994. History of 'biotechnology'. Nature 337, 10.
  9. Burstein, D., Harrington, L.B., Strutt, S.C., Probst, A.J., Anantharaman, K., Thomas, B.C., Doudna, J.A., Banfield, J.F., 2017. New CRISPR-Cas systems from uncultivated microbes. Nature 542, 237-241.
  10. Cabrera, C., et al., 2019. Electrochemical Proteus vulgaris whole cell urea sensor in synthetic urine. Current Research in Biotechnology https://doi.org/10.1016/j.crbiot.2019.1007.1002 (Accepted).
  11. Capaldo, A., Lavie, D., Messeni Petruzzelli, A., 2017. Knowledge maturity and the scientific value of innovations: the roles of knowledge distance and adoption. J. Manag. 43, 503-533.
  12. Cătană, C.-S., Atanasov, A.G., Berindan-Neagoe, I., 2018. Natural products with anti-aging po- tential: affected targets and molecular mechanisms. Biotechnol. Adv. 36, 1649-1656.
  13. Chenthamarakshan, A., Parambayil, N., Miziriya, N., Soumya, P., Lakshmi, M.K., Ramgopal, A., Dileep, A., Nambisan, P., 2017. Optimization of laccase production from Marasmiellus palmivorus LA1 by Taguchi method of design of experiments. BMC Biotechnol. 17, 12.
  14. Colson, G., Rousu, M.C., 2013. What do consumer surveys and experiments reveal and con- ceal about consumer preferences for genetically modified foods? GM Crops & Food 4, 158-165.
  15. Dalpé, R., 2002. Bibliometric analysis of biotechnology. Scientometrics 55, 189-213.
  16. de Almeida, L.G., de Moraes, L.A.B., Trigo, J.R., Omoto, C., Cônsoli, F.L., 2017. The gut micro- biota of insecticide-resistant insects houses insecticide-degrading bacteria: a potential source for biotechnological exploitation. PLoS One 12, e0174754.
  17. Duarte, J.H., de Morais, E.G., Radmann, E.M., Costa, J.A.V., 2017. Biological CO2 mitigation from coal power plant by Chlorella fusca and Spirulina sp. Bioresour. Technol. 234, 472-475.
  18. Eid, H.M., Wright, M.L., Anil Kumar, N., Qawasmeh, A., Hassan, S.T., Mocan, A., Nabavi, S.M., Rastrelli, L., Atanasov, A.G., Haddad, P.S., 2017. Significance of microbiota in obesity and metabolic diseases and the modulatory potential by medicinal plant and food ingredients. Front. Pharmacol. 8, 387.
  19. Erb, T.J., Jones, P.R., Bar-Even, A., 2017. Synthetic metabolism: metabolic engineering meets enzyme design. Curr. Opin. Chem. Biol. 37, 56-62.
  20. Gartland, K., Bruschi, F., Dundar, M., Gahan, P., Magni, M.V., Akbarova, Y., 2013. Progress towards the 'golden age' of biotechnology. Curr. Opin. Biotechnol. 24, S6-S13.
  21. Haider, A., Haider, S., Kang, I.-K., 2018. A comprehensive review summarizing the effect of electrospinning parameters and potential applications of nanofibers in biomedical and biotechnology. Arab. J. Chem. 11, 1165-1188.
  22. Jansen, M.L., Bracher, J.M., Papapetridis, I., Verhoeven, M.D., de Bruijn, H., de Waal, P.P., van Maris, A.J., Klaassen, P., Pronk, J.T., 2017. Saccharomyces cerevisiae strains for second- generation ethanol production: from academic exploration to industrial implementation. FEMS Yeast Res. 17, fox044.
  23. Karaffa, L., Kubicek, C.P., 2003. Aspergillus niger citric acid accumulation: do we understand this well working black box? Appl. Microbiol. Biotechnol. 61, 189-196.
  24. Karigar, C.S., Rao, S.S., 2011. Role of microbial enzymes in the bioremediation of pollutants: a review. Enzyme Research 2011, 805187.
  25. Kennedy, M.J., 1991. The evolution of the word 'biotechnology'. Trends Biotechnol. 9, 218-220.
  26. Kim, I., et al., 2019. Copper oxide (CuO) loaded polyacrylonitrile (PAN) nanofiber membranes for antimicrobial breath mask applications. Current Research in Biotechnology https:// doi.org/10.1016/j.crbiot.2019.1007.1001 (Accepted).
  27. Komor, A.C., Badran, A.H., Liu, D.R., 2017. CRISPR-based technologies for the manipulation of eukaryotic genomes. Cell 168, 20-36.
  28. Korman, T.P., Opgenorth, P.H., Bowie, J.U., 2017. A synthetic biochemistry platform for cell free production of monoterpenes from glucose. Nat. Commun. 8, 15526.
  29. Kruyer, N.S., Peralta-Yahya, P., 2017. Metabolic engineering strategies to bio-adipic acid pro- duction. Curr. Opin. Biotechnol. 45, 136-143.
  30. Kuppusamy, S., Sethurajan, M., Kadarkarai, M., Aruliah, R., 2017. Biodecolourization of tex- tile dyes by novel, indigenous Pseudomonas stutzeri MN1 and Acinetobacter baumannii MN3. J. Environ. Chem. Eng. 5, 716-724.
  31. Kwak, S., Jin, Y.-S., 2017. Production of fuels and chemicals from xylose by engineered Sac- charomyces cerevisiae: a review and perspective. Microb. Cell Factories 16, 82.
  32. Lassoued, R., et al., 2019. Risk and safety considerations of genome edited crops: expert opinion. Current Research in Biotechnology https://doi.org/10.1016/j.crbiot.2019.1008.1001 (Accepted).
  33. Magnusson, M.K., Hursti, U.-K.K., 2002. Consumer attitudes towards genetically modified foods. Appetite 39, 9-24.
  34. Mathieu, J.M., Schloendorn, J., Rittmann, B.E., Alvarez, P.J., 2009. Medical bioremediation of age-related diseases. Microb. Cell Factories 8, 21.
  35. Moeen, M., Agarwal, R., 2017. Incubation of an industry: heterogeneous knowledge bases and modes of value capture. Strateg. Manag. J. 38, 566-587.
  36. Pawar, R.S., Krynitsky, A.J., Rader, J.I., 2013. Sweeteners from plants-with emphasis on Stevia rebaudiana (Bertoni) and Siraitia grosvenorii (Swingle). Anal. Bioanal. Chem. 405, 4397-4407.
  37. Pawluk, A., Davidson, A.R., Maxwell, K.L., 2018. Anti-CRISPR: discovery, mechanism and function. Nat. Rev. Microbiol. 16, 12-17.
  38. Pronk, J.T., Lee, S.Y., Lievense, J., Pierce, J., Palsson, B., Uhlen, M., Nielsen, J., 2015. How to set up collaborations between academia and industrial biotech companies. Nat. Biotechnol. 33, 237-240.
  39. Saxena, V., Kumar, N., Saxena, V.K., 2017. A comprehensive review on combustion and stabil- ity aspects of metal nanoparticles and its additive effect on diesel and biodiesel fuelled CI engine. Renew. Sust. Energ. Rev. 70, 563-588.
  40. Sheldon, R.A., Woodley, J.M., 2017. Role of biocatalysis in sustainable chemistry. Chem. Rev. 118, 801-838.
  41. Singh, B.N., Gupta, V.K., Chen, J., Atanasov, A.G., 2017. Organic nanoparticle-based combina- tory approaches for gene therapy. Trends Biotechnol. 35, 1121-1124.
  42. Taheri, F., Azadi, H., D'Haese, M., 2017. A world without hunger: organic or GM crops? Sus- tainability 9, 580.
  43. van Eck, N.J., Waltman, L., 2009. Software survey: VOSviewer, a computer program for bibliometric mapping. Scientometrics 84, 523-538.
  44. Vendruscolo, F., da Rocha Ferreira, G.L., Antoniosi Filho, N.R., 2017. Biosorption of hexavalent chromium by microorganisms. Int. Biodeterior. Biodegradation 119, 87-95.
  45. Ververidis, F., Trantas, E., Douglas, C., Vollmer, G., Kretzschmar, G., Panopoulos, N., 2007. Biotechnology of flavonoids and other phenylpropanoid-derived natural products. Part II: reconstruction of multienzyme pathways in plants and microbes. Biotechnology Jour- nal: Healthcare Nutrition Technology 2, 1235-1249.
  46. Yeung, A.W.K., Goto, T.K., Leung, W.K., 2017. The changing landscape of neuroscience re- search, 2006-2015: a bibliometric study. Front. Neurosci. 11, 120.
  47. Yeung, A.W.K., Aggarwal, B., Barreca, D., Battino, M., Belwal, T., Horbańczuk, O., Berindan- Neagoe, I., Bishayee, A., Daglia, M., Devkota, H., et al., 2018a. Dietary natural products and their potential to influence health and disease including animal model studies. Anim. Sci. Paper Rep. 36, 345-358.
  48. Yeung, A.W.K., Tzvetkov, N.T., Atanasov, A.G., 2018b. When neuroscience meets pharmacol- ogy: a neuropharmacology literature analysis. Front. Neurosci. 12, 852.
  49. Yeung, A.W.K., Tzvetkov, N.T., Zengin, G., Wang, D., Xu, S., Mitrović, G., Brnčić, M., Dall'Acqua, S., Pirgozliev, V., Kijjoa, A., et al., 2019a. The berries on the top. Journal of Berry Research 9, 125-139.
  50. Yeung, A.W.K., Horbańczuk, M., Tzvetkov, N.T., Mocan, A., Carradori, S., Maggi, F., Marchewka, J., Sut, S., Dall'Acqua, S., Gan, R.-Y., et al., 2019b. Curcumin: total-scale analysis of the scientific literature. Molecules 24, 1393.
  51. Yeung, A.W.K., Aggarwal, B.B., Orhan, I.E., Horbańczuk, O.K., Barreca, D., Battino, M., Belwal, T., Bishayee, A., Daglia, M., Devkota, H.P., et al., 2019c. Resveratrol, a popular dietary supplement for human and animal health: quantitative research literature analy- sis -a review. Anim. Sci. Paper Rep. 37, 103-118.
  52. You, C., Shi, T., Li, Y., Han, P., Zhou, X., Zhang, Y.H.P., 2017. An in vitro synthetic biology plat- form for the industrial biomanufacturing of myo-inositol from starch. Biotechnol. Bioeng. 114, 1855-1864.
  53. Zhou, P., Li, M., Shen, B., Yao, Z., Bian, Q., Ye, L., Yu, H., 2019. Directed coevolution of β- carotene ketolase and hydroxylase and its application in temperature-regulated biosyn- thesis of astaxanthin. J. Agric. Food Chem. 67, 1072-1080.

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    Atanas G Atanasov

    Frontiers in Public Health, 2020

    Objective: Medical errors represent a leading cause of patient morbidity and mortality. The aim of this study was to quantitatively analyze the existing scientific literature on medical errors in order to gain new insights in this important medical research area. Study Design: Web of Science database was used to identify relevant publications, and bibliometric analysis was performed to quantitatively analyze the identified articles for prevailing research themes, contributing journals, institutions, countries, authors, and citation performance. Results: In total, 12,415 publications concerning medical errors were identified and quantitatively analyzed. The overall ratio of original research articles to reviews was 8.1:1, and temporal subset analysis revealed that the share of original research articles has been increasing over time. The United States contributed to nearly half (46.4%) of the total publications, and 8 of the top 10 most productive institutions were from the United States, with the remaining 2 located in Canada and the United Kingdom. Prevailing (frequently mentioned) and highly impactful (frequently cited) themes were errors related to drugs/medications, applications related to medicinal information technology, errors related to critical/intensive care units, to children, and mental conditions associated with medical errors (burnout, depression). Conclusions: The high prevalence of medical errors revealed from the existing literature indicates the high importance of future work invested in preventive approaches. Digital health technology applications are perceived to be of great promise to counteract medical errors, and further effort should be focused to study their optimal implementation in all medical areas, with special emphasis on critical areas such as intensive care and pediatric units.

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