Papers by Ghazaleh Moghaddam
Milk is an important source of all basic nutrients required for mammals including human beings. T... more Milk is an important source of all basic nutrients required for mammals including human beings. The study was conducted to evaluate physiochemical quality of milk samples in selected dairy plant of Iran. Various physiochemical properties of milk were analyzed by Lactostar analyzer and compared to the related standards. Also another major concern of this study was to consider the presence of melamine in milk samples by high-performance liquid chromatography. The method was performed using a C8 column and detection at 240 nm. Total 38 different milk samples were analyzed. The results for milk sample analysis showed fat 2.17±0.05%, protein 2.89%±0.01%, lactose 4.37%±0.02%, total solid 10.66%±0.06%, and mineral of 0.22%±0.05% and in infant samples fat 23.38±4.25%, protein 24.18%±3.86%, lactose 37.33%±6.26%, total solid 91.32%±6.26%, and mineral of 16.17%±7.25%. To conclude the occurrence of melamine in infant milk samples and pasteurized milk samples collected from Tehran-Iran revealed ...
Health, 2013
Complete removal of smear layer and debris during the process of root canal therapy is of paramou... more Complete removal of smear layer and debris during the process of root canal therapy is of paramount importance in order to achieve the objectives of endodontic treatment. The aim of this study was to compare the amount of extruded debris and smear layer using two widespread rotary nickel-titanium instruments. Fifty eight freshly extracted human mandibular first molar mesial canals were randomly assigned into two groups. The root canals were instrumented using Mtwo (VDW, Munich, Germany), and BioRaCe (FKG Dentaire, LaChauxde-Fonds, Switzerland) NiTi instruments. Debris and smear layer from the apical thirds part during instrumentation were evaluated by scanning electron microscope. Then, the scores of remaining debris and smear layer were calculated for each group and compared. Data were then statistically analyzed using Mann-Whitney U test. There were significant differences in the amount of smear layer among two groups (P < 0.05). The greatest amount of apical debris was extruded by the BioRaCe group and the least by the Mtwo group. The results of the present study showed that, although both instrumentation techniques apically extruded debris and smear layer through the apical foramen, the Mtwo instruments induced less extruded debris and smear layer than the BioRaCe rotary systems.
Determination of Synthetic Food Colors, Caffeine, Sodium Benzoate and Potassium Sorbate in Sports Drinks
Tropical Journal of Pharmaceutical Research, 2016
Determination of 8 Synthetic Food Dyes by Solid Phase Extraction and Reversed-Phase High Performance Liquid Chromatography
Tropical Journal of Pharmaceutical Research, 2016
Iranian journal of pharmaceutical research (IJPR)
Date is one of the world's oldest food-producing plants wich has always played an important role ... more Date is one of the world's oldest food-producing plants wich has always played an important role in the economy and social life. Various researchers examined chemical composition and nutritional values of edible parts of dates while limited information about chemical composition and nutritional quality of date seed is available. In this study, fatty acid composition and total tocopherol content of 14 Iranian date seed oils were studied. Statistical analysis was performed through SPSS computing package. According to the fatty acid profiles, seven fatty acids were found through nearly 50% oleic acid in seeds. Shekar cultivar by 51.40% had the maximum amount and Lasht cultivar by 33.38% had the minimum amount of oleic acid. Tocopherol content in the samples varied between 33.86 µg vit E/g oil for Shahabi2 to 10.09 µg vit E/g oil for Shekar. Tocopherol content was 1.88 and 0.61 µg respectively in one-gram seed of these two cultivars. Iranian date seed oils classified as oleic-lauric oil, had a high amount of oleic acid and could serve as a profitable source of valuable oils for industrial applications.
The aim of this study was to investigate the fatty acids profile of five sesame cultivars includi... more The aim of this study was to investigate the fatty acids profile of five sesame cultivars including Branching Naz, Darab, Karaj, Dezful and Black sesame and the effect of time and temperature roasting procedure. The seeds oil content varied from 43±0.28 to 47±0.41% with the average content of 44.4±1.87%. Darab and Black sesame cultivar had the highest and lowest oil content respectively. Oleic and linoleic acids were the two-dominant fatty acids in the sesame seed oil about 80 to 85% of the total amount, whereas palmitic and stearic acids were present at 12 to 15%. Moreover, Dazful and Black sesame had the maximum and minimum content of oxidizability value respectively. The results of the present study showed that the fatty acid contents in studied cultivars were steady during different roasting conditions and fatty acid behavior of samples was good fitted with the high temperatures.
Journal of Chemistry
Tragopogon graminifolius DC. (TG), Compositae family, is traditionally used for the treatment of ... more Tragopogon graminifolius DC. (TG), Compositae family, is traditionally used for the treatment of various diseases like gastrointestinal and hepatic disorders. The aim of the present study is to standardize extracts from TG used for preparation of different dosage forms in traditional Iranian medicine (TIM) based on phenolic compounds. For this purpose, total phenolic content and some phenolic compounds were determined in ethanolic extracts from aerial part and root of TG by HPLC method. Furthermore, antioxidant activity was evaluated using DPPH-HPLC methods. Caffeic acid, gallic acid, ρ-coumaric acid, ferulic acid, and catechin were detected in root and aerial part of TG. ρ-Coumaric acid (6.357 ± 0.014 mg·g−1) was dominant phenolic compound in aerial part followed by ferulic acid (1.24 ± 0.018 mg·g−1). Also, ρ-coumaric acid (2.685 ± 0.031 mg·g−1) was highly abundant in root, followed by catechin (2.067 ± 0.021 mg·g−1). Antioxidant activity of root extract (460.45 ± 0.78 µg Vit.E.E·m...
Analytical Chemistry Letters, 2015
The effects of vinegar and oxymel solutions (used in Iranian traditional medicine) and processing... more The effects of vinegar and oxymel solutions (used in Iranian traditional medicine) and processing temperatures (75, 85 and 100°C) on the milk coagulation was studied to identify and determine the protein indicators of resulting whey. The HPLC (high performance liquid chromatography) analysis showed that the α-lactalbumin (ALA) and β-lactoglobulin (BLG) contents of resulting whey reduced significantly, when the coagulation temperature increased from 75 to 100 o C. In both solutions and at 75 o C processing temperature, the BLG of final whey protein was significantly more (~ 60-70 %) than ALA content. The reverse process happened at 85 o C, and the ALA content became much higher than BLG. A significantly higher content of ALA was recovered once the combination of oxymel and vinegar solutions with milk reached to respectivelỹ 10 and 0.3 % and milk protein was coagulated at 85 o C. Overall, there is a good possibility to make a milk whey with high content of desirable ALA and negligible concentrations of BLG to convert cow's milk proteins to human's milk as it was the main intention in Iranian Traditional Medicine method.
Tropical Journal of Pharmaceutical Research, 2014
Methods: Male Wistar rats, 175 -220 g, were fasted for 48 h, but had free access to water. They w... more Methods: Male Wistar rats, 175 -220 g, were fasted for 48 h, but had free access to water. They were randomly divided into nine experimental groups. Ulcer was induced in the rats with 80 % ethanol. The control group animals received the same treatment as those in the test groups except that the extract treatment was replaced by administration of appropriate volume of the dosing vehicle. Histaminereceptor type-2 (H2) blocker, cimetidine (100 mg/kg, i.p.) was used as the reference drug. Oral pretreatment with three different extract doses (25, 50 and 100 mg/kg) was for 15 days, thereafter, ulcer index (UI) and inhibition were calculated. Results: The extract, at 50 mg/kg, of black fruit peel extract produced significant (p < 0.05) protective effect in rats with a preventive index of 65.87 %. Other doses were significantly protective against ethanol-induced gastric ulcer in the rats. On the other hand, north white peel was not effective (50 mg/kg) showed an ulcer index of 49.52 ± 1.99. Histopathological examination of the stomach of the ulcerated animals treated with white peel (50 mg/kg) showed severe erosion of gastric mucosa, submucosal edema and neutrophil infiltration. Conclusion: The study shows indicates the antiulcer properties of the methanol extracts of north white peel, sour summer and black peel (25, 50, 100 mg/kg) of pomegranate. Their antiulcer activity is exerted, possibly, via its high antioxidant activity.
Anti-Ulcerogenic Activity of the Pomegranate Peel (<i>Punica granatum</i>) Methanol Extract
Food and Nutrition Sciences, 2013
Iranian journal of pharmaceutical research : IJPR, 2012
Date is one of the world's oldest food-producing plants wich has always played an important r... more Date is one of the world's oldest food-producing plants wich has always played an important role in the economy and social life. Various researchers examined chemical composition and nutritional values of edible parts of dates while limited information about chemical composition and nutritional quality of date seed is available. In this study, fatty acid composition and total tocopherol content of 14 Iranian date seed oils were studied. Statistical analysis was performed through SPSS computing package. According to the fatty acid profiles, seven fatty acids were found through nearly 50% oleic acid in seeds. Shekar cultivar by 51.40% had the maximum amount and Lasht cultivar by 33.38% had the minimum amount of oleic acid. Tocopherol content in the samples varied between 33.86 μg vit E/g oil for Shahabi2 to 10.09 μg vit E/g oil for Shekar. Tocopherol content was 1.88 and 0.61 μg respectively in one-gram seed of these two cultivars. Iranian date seed oils classified as oleic-lauric...
Tragopogon graminifolius DC. (TG), Compositae family, is traditionally used for the treatment of ... more Tragopogon graminifolius DC. (TG), Compositae family, is traditionally used for the treatment of various diseases like gastrointestinal and hepatic disorders. The aim of the present study is to standardize extracts from TG used for preparation of different dosage forms in traditional Iranian medicine (TIM) based on phenolic compounds. For this purpose, total phenolic content and some phenolic compounds were determined in ethanolic extracts from aerial part and root of TG by HPLC method. Furthermore, antioxidant activity was evaluated using DPPH-HPLC methods. Caffeic acid, gallic acid, -coumaric acid, ferulic acid, and catechin were detected in root and aerial part of TG. -Coumaric acid (6.357 ± 0.014 mg⋅g −1 ) was dominant phenolic compound in aerial part followed by ferulic acid (1.24 ± 0.018 mg⋅g −1 ). Also, -coumaric acid (2.685 ± 0.031 mg⋅g −1 ) was highly abundant in root, followed by catechin (2.067 ± 0.021 mg⋅g −1 ). Antioxidant activity of root extract (460.45 ± 0.78 g Vit.E.E⋅mL −1 ) was better than that of aerial part. Generally, phenolic compounds are one of the major constituents of TG and could be used as markers for standardization of dosage forms prepared from this plant. Also, TG demonstrated significant antioxidant activity using DPPH-HPLC method. Phenolic compounds of TG may be responsible for its marked antioxidant properties.
Iranian journal of pharmaceutical research : IJPR, 2011
Vitamin E is a potent reactive oxygen metabolites (ROM) scavenger. It is a lipid-soluble vitamin ... more Vitamin E is a potent reactive oxygen metabolites (ROM) scavenger. It is a lipid-soluble vitamin and its main function is to protect polyunsaturated fatty acids against oxidative stress. Twenty-five mechanically ventilated Intensive Care Unit (ICU) adult patients participated in a prospective randomized clinical trial receiving either placebo (10 patients) or 3 IM doses (1000 IU each) of vitamin E (15 patients). We determined plasma and bronchoalveolar lavage (BAL) fluid concentrations of vitamin E and superoxide dismutase (SOD). Among these 25 patients, there were 14 men and 11 women, aged 63.16 ±15.48 years (mean ± SD; range = 33 to 87 years). Vitamin E supplementation resulted in significant differences in plasma and BAL vitamin E concentrations between the two groups (p-value = 0.01, 0.01), decrease in SOD activities (not differ significantly in plasma (p-value = 0.23)), but with significant differences in BAL (p-value = 0.016) and progressive reduction in Acute Physiology and C...
Total Phenolic, Flavonoids, Tannin Content and Antioxidant Power of Some Iranian Pomegranate Flower Cultivars (<i>Punica granatum</i> L.)
American Journal of Plant Sciences, 2013
Trans Fatty Acids Profile in Different Commercial Brands of Margarine
Analytical Chemistry Letters, 2014
ABSTRACT
Total Antioxidant Activity, and Hesperidin, Diosmin, Eriocitrin and Quercetin Contents of Various Lemon Juices
Tropical Journal of Pharmaceutical Research, 2014
ABSTRACT Export Date: 18 October 2014
Fatty Acid Profile and Oxidation Parameters of Liquid Frying Oils
Analytical Chemistry Letters, 2013
ABSTRACT
Pakistan Journal of Biological Sciences, 2013
Food and Nutrition Sciences, 2013
Clinical and epidemiologic studies showed that among dietary factors the type of fatty acids (FAs... more Clinical and epidemiologic studies showed that among dietary factors the type of fatty acids (FAs) in the diet plays an important role in determining risk of chronic disease. The aim of our study was to determine the levels of Trans FA (TFA) in edible oil samples consumed in Tehran, Iran analyzed by gas chromatograph (GC). The mean of total TFA was 0.45% ranging from (0.11% -1.61%) for liquid frying oils and 2.92% ranging from (0.46% -5.40%) for solid oils. The major TFA observed in these two groups was elaidic acid in solid oils. The highest content of total saturated fatty acid (SFA) was detected in solid oils with average of 32.07 and palmitic acid was the major SFA in these four groups. Linoleic and linolenic acid are the most important poly unsaturated fatty acid (PUFA). The variance in the percentage of TFA in the edible oils probably resulted from differences in the type of oils, quality, heating, processing technique and storage condition of the edible oils. The results indicated that, edible oils contain considerable proportions of trans fatty acids. Therefore, it is important to assess the content of TFA in edible oils in Iran.
Characterization of different olive pulp and kernel oils
Journal of Food Composition and Analysis, 2012
ABSTRACT In this paper, the tocopherol contents, fatty-acid compositions and some oxidation index... more ABSTRACT In this paper, the tocopherol contents, fatty-acid compositions and some oxidation indexes of olive (Olea europaea L.) pulp and kernel oils, originating from six cultivars, were determined. The tocopherol contents varied from 110 ± 7.34 to 358 ± 3.86 μg/g in pulp oil and from 15.0 ± 0.17 to 38.8 ± 0.27 μg/g in kernel oil. The major fatty acid in all cultivars was oleic acid, along with two other predominant fatty acids, palmitic and linoleic. The PCA results showed that the fatty acid profiles are similar in pulp and kernel. The calculated oxidizability value of the kernel oils was slightly worse than those of the pulp oils. However, the kernel oils have favorable values for the saturated fatty acid contents and for the unsaturated/saturated fatty acids ratio. The main outcome of this study revealed that the kernel oils can be used as suitable edible oils, with low tocopherol content, but with a more favorable fatty acids composition than their corresponding pulp oils.
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Papers by Ghazaleh Moghaddam