Papers by Guillermo Delgado-García
Gaceta medica de Mexico
The roman philonium (Philonium Romanum) is an example of pharmacological poetry. This opiate was ... more The roman philonium (Philonium Romanum) is an example of pharmacological poetry. This opiate was conceived by Philo of Tarsus, who was active during the first century of the Common Era. His antidote was written in elegiac couplets. The conservation of these couplets is owed to Galen, who reproduced them in the ninth book of On the Composition of Medicines according to the Places. Most of this Galenic treatise has not been translated into Spanish. For the first time, we offer this prescription in our language from a French version of the fin de siècle. Additionally, we attempt an exegesis of Philo's poem.
Reader response: Association of transient orthostatic hypotension with falls and syncope in patients with Parkinson’s disease
Gaceta Medica De Mexico, 2012
S. Basch (1837-1905) succeeded F. Semeleder as personal physician to the Mexican emperor. The new... more S. Basch (1837-1905) succeeded F. Semeleder as personal physician to the Mexican emperor. The newly appointed imperial physician had been a pupil of Brucke (1819-1892) in Vienna. After the death of the emperor, Basch returned to Europe, where he would study under the guidance of K. Ludwig (1816-1895). Thereafter he invented the sphygmomanometer in Berlin.
Gaceta Medica De Mexico, 2016
According to the testimony of Ptolemy, which we know through Arrian, it has been assumed that Ale... more According to the testimony of Ptolemy, which we know through Arrian, it has been assumed that Alexander the Great suffered a pneumothorax during his campaign against the Malli. In general, this assumption has been interpreted as a historical fact in medical literature. We consulted the same sources and concluded that it is unlikely that Alexander’s arrow wound had given him a pneumothorax. In addition, we stressed the extra-historical content of classical sources. (Gac Med Mex. 2016;152:843-9) Corresponding author: Guillermo Delgado-García, grdelgadog@gmail.com; guillermo.delgadogr@uanl.edu.mx
Between Weir Mitchell and Autoimmunity: Donato Alarcón-Segovia’s Contribution to the Study of Erythromelalgia (P5.314)
Neurology, 2018
Objective: To explore the contribution of the Mexican rheumatologist Donato Alarcon-Segovia (1935... more Objective: To explore the contribution of the Mexican rheumatologist Donato Alarcon-Segovia (1935–2004) to the study of erythromelalgia. Background: Silas Weir Mitchell (1829–1914) first described erythromelalgia in 1878. Prof. Alarcon-Segovia, who received the Mayo Clinic Distinguished Alumni Award in 1999, had a great interest in erythromelalgia throughout his fruitful academic career. This facet has not been systematically analyzed. Design/Methods: All articles published by Alarcon-Segovia addressing erythromelalgia were reviewed. Content and bibliographic analysis was conducted. Results: Six articles were identified (1963–1993) in MEDLINE/PubMed. Alarcon-Segovia was the first author on four occasions. The first half was done at Mayo Clinic (Rochester, Minnesota) and the second half at the National Institute of Medical Sciences and Nutrition (Mexico City). These articles were published in Archives of Internal Medicine (currently JAMA Internal Medicine ) ( n =2), Circulation , The...
Aportación neurológica de Manuel Acuña
Gaceta Medica De Mexico, 2015
espanolJose Maria Barcelo de Villagran (1819-1872) fue el primer profesor de anatomia topografica... more espanolJose Maria Barcelo de Villagran (1819-1872) fue el primer profesor de anatomia topografica en Mexico. El poeta mexicano Manuel Acuna (1849-1873) estuvo entre sus alumnos. Tras la muerte de su maestro, Acuna escribio una monografia titulada Anatomia topografica. La cavidad cefalo-raquidiana (1893). Por primera vez se discute su contenido y trascendencia. EnglishJose Maria Barcelo de Villagran (1819-1872) was the first Professor of Topographic Anatomy in Mexico. The Mexican poet Manuel Acuna (1849-1873) was among his students. After the death of his mentor, Acuna wrote a monograph entitled “Topographic Anatomy. The Cephalo-Rachidian Cavity” (1893). For the first time we discuss the content and significance of this monograph. (Gac Med Mex. 2015;151:426-9) Corresponding author: Guillermo Delgado, guillermo.delgadogr@uanl.edu.mx
Dos clases de apoplejía en la prensa novohispana
En 1787, tres medicos novohispanos citaron un fragmento de Le Clerc (1726-1798) en la Gazeta de M... more En 1787, tres medicos novohispanos citaron un fragmento de Le Clerc (1726-1798) en la Gazeta de Mexico. Ahi el frances enumera seis casos particulares en los que la sangria es muchas veces mortal, incluyendo dos clases de apoplejia: la serosa y la lactea. Ambas condiciones morbosas son hoy en dia ignoradas por el grueso de los especialistas en neurologia, por lo que efectuamos una revision historica de estos padecimientos
espanolEl filonio romano (Philonium Romanum) es un ejemplo de poesia farmacologica. Esta opiata f... more espanolEl filonio romano (Philonium Romanum) es un ejemplo de poesia farmacologica. Esta opiata fue concebida por Filon de Tarso, activo durante el primer siglo de nuestra era. El medico de Tarso compuso su antidoto en disticos elegiacos. Debemos a Galeno la conservacion de estos disticos, pues los reprodujo en el noveno libro de Sobre la composicion de los medicamentos segun los lugares. La mayor parte de este tratado galenico no se ha traducido al espanol. A partir de una version francesa de fin de siglo vertimos por primera vez esta receta a nuestro idioma. Ofrecemos posteriormente una exegesis del poema de Filon. EnglishThe Roman philonium (Philonium Romanum) is an example of pharmacological poetry. This opiate was conceived by Philo of Tarsus, who was active during the first century of the Common Era. His antidote was written in elegiac couplets. The conservation of these couplets is owed to Galen, who reproduced them in the ninth book of On the Composition of Medicines accordi...
Journal of Rheumatic Diseases, 2018
Extensor plantar response elicited by neck extension
Acta Neurologica Belgica, 2021
Neurology, 2020
is an editorial team member of the Neurology Resident & Fellow Section. Antonio Arauz reports no ... more is an editorial team member of the Neurology Resident & Fellow Section. Antonio Arauz reports no disclosures relevant to the manuscript. Teresa Corona reports no disclosures relevant to the manuscript. Study funding: No targeted funding reported. Background and significance Coronavirus disease 2019 (COVID-19) is at present a global pandemic. As COVID-19 cases rise in our different countries, neurologists and neurologists-in-training will be increasingly involved in the care of these patients from both a general medical and neurologic perspective. In the same way, patients with pre-exiting neurologic conditions are in no way exempt from acquiring this infection. On the other hand, new-onset neurologic manifestations have also been recently reported in previously healthy people infected with SARS-CoV-2. 1 This is why it is currently essential for neurologists and neurologists-intraining to be aware of the repercussion that COVID-19 may have in our daily practice. Herman et al recently reported in the journal a scoping review on COVID-19 and neurological practice. 1 This review displayed the current panorama in brief and simple terms. Its concise results are one way to continue caring for these patients in a better-informed way. Syntheses like this one are vital when evidence is rapidly changing, especially during this season when many neurologists are directly treating patients with COVID-19 and they don't have enough time to read all relevant articles coming out every day. Therefore, this
Neuroimmunology and Neuroinflammation, Nov 9, 2017
Arquivos de Neuro-Psiquiatria, 2019
Huntington disease (HD) is an autosomal dominant genetic disorder characterized by movement disor... more Huntington disease (HD) is an autosomal dominant genetic disorder characterized by movement disorders, cognitive impairment, and psychiatric symptoms. Relatives of HD patients experience a great burden as the latter suffer from altered social conduct and deterioration of interpersonal relationships. Theory of mind (ToM) is the ability to attribute mental states (to oneself and others). Deficits in ToM are thought to have a role in the changes in empathy and interpersonal difficulties that HD patients face. Methods: We conducted a cross sectional study to compare ToM task scores of patients with mild to moderate HD, their relatives (spouse or at-risk first-degree relative with a negative gene test) and controls.Individuals with dementia or depression were excluded. The ToM test battery included Spanish versions of the Reading Mind in the Eyes Test (RMET), Happé's Strange Stories (Social and Physical Stories subtests) and the Hinting Task. Results: The series comprised 12 HD patie...
Las dos caras del reflejo venoarteriolar: vasoconstricción y vasodilatación cutánea al bajar y subir el brazo
Revista de Neurología, 2016
Introduccion. El reflejo venoarteriolar (RVA) lo provoca un incremento en la presion venosa trans... more Introduccion. El reflejo venoarteriolar (RVA) lo provoca un incremento en la presion venosa transmural al colocar una parte del cuerpo en el sentido de la aceleracion gravitatoria por debajo del corazon. Objetivo. Evaluar el RVA en sujetos sanos al levantar una parte del cuerpo por encima del corazon. Sujetos y metodos. En 16 sujetos sanos (20-65 anos) se estudio el RVA mediante cambios en el flujo sanguineo de la piel con un fotopletismografo digital infrarrojo colocado en el pulpejo en sujetos sanos durante las siguientes condiciones: brazo derecho a la altura del corazon, brazo derecho 40 cm por debajo del corazon y brazo derecho 40 cm por encima del corazon. Las variables medidas fueron: amplitud del flujo sanguineo de la piel con el brazo a la altura del corazon (amplitud basal), porcentaje de disminucion del flujo sanguineo de la piel con el brazo por debajo del corazon y porcentaje de aumento del flujo sanguineo de la piel con el brazo por encima del corazon. Resultados. El porcentaje de vasoconstriccion con el brazo derecho por debajo del corazon fue del 35%, y el de vasodilatacion, del 50%. Conclusiones. La evaluacion del RVA con el brazo por debajo del corazon provoca vasoconstriccion, y la elevacion del brazo produce una importante vasodilatacion. La vasoconstriccion y la vasodilatacion se mantienen mientras la extremidad se mantenga por encima o por debajo del corazon. Este es un estudio potencialmente muy util y economico para estudiar la inervacion de la microcirculacion en diversas neuropatias perifericas de fibras delgadas y mixtas.
Clinical Neurophysiology, 2018
Clinical Neurophysiology, 2018
however, these differences were not significant. Treatment changed in 22.4% of EMU and 34.1% of A... more however, these differences were not significant. Treatment changed in 22.4% of EMU and 34.1% of AEEG patients (p-value = 0.10). Conclusion: These data suggest that 24 h AEEG is non-inferior to 24 h EMU evaluation. The lower EEG fee and absence of other hospital costs suggests AEEG is of higher value than EMU for certain nonsurgical indications.
Multiple Sclerosis and Related Disorders, 2018
Close to half of the patients with previous pregnancies reported at least one gestational loss.... more Close to half of the patients with previous pregnancies reported at least one gestational loss. This percentage is higher than expected for their age group in our country. Most of these pregnancy losses occurred years before the diagnosis of NMO. AQP4-IgG can be detected in serum more than 10 years before the NMO onset and can cause miscarriage by binding to placental AQP4, activating complement, and causing inflammatory infiltration.
Two kinds of apoplexy in the Colonial press
Gaceta medica de Mexico
In 1787, three Colonial physicians quoted from Le Clerc (1726-1798) in the Gazeta de México. The ... more In 1787, three Colonial physicians quoted from Le Clerc (1726-1798) in the Gazeta de México. The French author lists six specific cases where bloodletting is often fatal, including two kinds of apoplexy: the serous and the lacteal. Both conditions are nowadays unknown to the majority of specialists in clinical neurology, and we therefore conducted an historical review of these conditions.
Arquivos de neuro-psiquiatria, 2017
The Argentinian author Silvina Ocampo (1903-1993) left us a vast body of works which are consider... more The Argentinian author Silvina Ocampo (1903-1993) left us a vast body of works which are considered outstanding in many ways. In 1960, she published a short story, entitled "El médico encantador" (The Charming Physician), in the renowned literary magazine Sur. The central character of this piece is a family doctor named Albino Morgan, who had a secret truth: in any house he visited, all variety of disease also entered. He brought with him the viruses he disseminated. The narrator of this short story-one of his patients-describes four of Morgan's diseases. These imaginary neurological conditions allowed Ocampo to explore improbable situations in everyday life.
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Papers by Guillermo Delgado-García