This study explores the hydrogenation of CO2 into liquid hydrocarbons using a CoFe/HZSM-5 tandem ... more This study explores the hydrogenation of CO2 into liquid hydrocarbons using a CoFe/HZSM-5 tandem catalyst, with insights into the role of synergetic efficiency in enhanced selectivity.
In the presence of dry ice, a series of graphitic materials with carboxylated edges (ECGs) were s... more In the presence of dry ice, a series of graphitic materials with carboxylated edges (ECGs) were synthesized by ball milling graphite for varied times (24, 36, and 46 h). The influence of carboxylation on the physiochemical characteristics and electrochemical performance as effective electrodes for supercapacitors were assessed and compared with pure graphite. Several characterization techniques were employed to investigate into the morphology, texture, microstructure, and modification of the materials. Due to its interconnected micro-mesoporous carbon network, which is vital for fast charge-discharge at high current densities, storing static charges, facilitating electrolyte transport and diffusion, and having excellent rate performance, the ECG-46 electrode among the investigated samples achieved the highest specific capacitance of 223 F g−1 at 0.25 A g−1 current density and an outstanding cycle stability, with capacitance retention of 90.8% for up to 10,000 cycles. Furthermore, th...
Many pharmaceutical products have been reported to be substandard and counterfeit. About 15% of a... more Many pharmaceutical products have been reported to be substandard and counterfeit. About 15% of all drugs circulating in some parts of Africa and Asia are believed to be counterfeit, with figures rising to as high as 50%. This study was therefore carried out to assess the quality of five groups of drugs of different brands manufactured by pharmaceutical companies in Nigeria. Qualitative and quantitative analysis were carried out on the drugs using United States, British and Indian Pharmacopoeias. Qualitative analysis investigated includes: friability test, hardness test, disintegration test, dissolution test, pH, and weight uniformity for tablets; specific gravity, flow rate, pH and weight per ml of syrups. The quantitative analysis includes percentage purity and drug assay determination for different constituents using titrimetric, spectrophotometric and high performance liquid chromatographic (HPLC) methods. From the study, it was established that the Nigeria brands of pharmaceuti...
Old drugs for a new indication: a review of chloroquine and analogue in COVID-19 treatment
Porto Biomedical Journal, 2021
As an innovative therapeutic strategy, drug repurposing affords old, approved, and already establ... more As an innovative therapeutic strategy, drug repurposing affords old, approved, and already established drugs a chance at new indications. In the wake of the COVID-19 pandemic and the accompanied urgency for a lasting treatment, drug repurposing has come in handy to stem the debilitating effects of the disease. Among other therapeutic options currently in clinical trials, chloroquine (CQ) and the hydroxylated analogue, hydroxychloroquine (HCQ) have been frontline therapeutic options in most formal and informal clinical settings with varying degrees of efficacy against this life-threatening disease. Their status in randomized clinical trials is related to the biochemical and pharmacological profiles as validated by in vitro, in vivo and case studies. With the aim to bear a balance for their use in the long run, this review not only synopsizes findings from recent studies on the degrees of efficacy and roles of CQ/HCQ as potential anti-COVID-19 agents but also highlights our perspectiv...
Bamboo, a perennial woody grass belonging to Gramineae family and Bambuseae subfamily, is ubiquit... more Bamboo, a perennial woody grass belonging to Gramineae family and Bambuseae subfamily, is ubiquitous in many parts of the world. This biomass possesses high potential as a substitute for many lignocellulosic and non-lignocellulosic materials in various capacities of applications owing to its chemical composition as well as its physical properties. Its abundance, chemical composition and numerous applications are reviewed in this work. This chapter also examined some investigated chemical modifications through alkali hydrolysis, acid hydrolysis, coupling to enhance properties of bamboo fibre for specialised applications.
The usage of synthetic-based inhibitors for protection of metals against corrosion is always acco... more The usage of synthetic-based inhibitors for protection of metals against corrosion is always accompanied by environmental and economic challenges, including a threat to human health. Therefore, the corrosion inhibition efficiency of sweet prayer (Thaumatococcus danielli) leaf extract on mild steel in alkaline medium (NaOH) was investigated. The effects of temperature and concentration of the inhibitor on corrosion inhibitive potential of the leaf extract were evaluated. The equilibrium data were subjected to isotherm analysis (Langmuir, Freundlich and Temkin models). Langmuir model was the best model that provided information on the adsorption of the corrosion systems. The values of Langmuir equilibrium constant (KL) increased from 0.1581 g/L to 0.6523 g/L as the temperature increased from 298 K to 333 K. The findings revealed that sweet prayer leaf extract at different concentrations had inhibitive effects of mild steel on alkaline medium. The values of activation energy of the inh...
This is a PDF file of an article that has undergone enhancements after acceptance, such as the ad... more This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
Background Withania somnifera (L.) Dunal (W. somnifera) is a herb commonly known by its English n... more Background Withania somnifera (L.) Dunal (W. somnifera) is a herb commonly known by its English name as Winter Cherry. Africa is indigenous to many medicinal plants and natural products. However, there is inadequate documentation of medicinal plants, including W. somnifera, in Africa. There is, therefore, a need for a comprehensive compilation of research outcomes of this reviewed plant as used in traditional medicine in different regions of Africa. Methodology Scientific articles and publications were scooped and sourced from high-impact factor journals and filtered with relevant keywords on W. somnifera. Scientific databases, including GBIF, PubMed, NCBI, Google Scholar, Research Gate, Science Direct, SciFinder, and Web of Science, were accessed to identify the most influential articles and recent breakthroughs published on the contexts of ethnography, ethnomedicinal uses, phytochemistry, pharmacology, and commercialization of W. somnifera. Results This critical review covers the ...
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