Papers by Soban Ahmad Faridi
Nanoscience & Nanotechnology-Asia, 2022
Nanoparticles have a wide range of responsive reactions in bacterial cells depending on their cha... more Nanoparticles have a wide range of responsive reactions in bacterial cells depending on their characteristics. They interact with organisms at a cellular level and are capable of producing unexpected reactions depending on their own and cell's morphological features. Some functions provide betterment of cells and some cause disruptions in the cell functioning or exhibit toxicity for them. Nanoparticles, depending on their toxicity, can also cause alterations in cellular physiology. Different nanoparticles affect different biological species in different ways. As a result, a comprehensive investigation is necessary for all types of nanoparticles to demonstrate their beneficial and harmful effects on various species in terms of growth, inhibition, toxicity, and death. In this review, we have only focused on the iron nanoparticle and their effects on bacterial cells as they are the most commonly used nanoparticle in biology and microbiology because of their unique physicochemical properties (size, shape, stability, etc.). These properties of NPs allow them to react with the bacterial cell surfaces and create a response (which can either support the growth of the bacteria or cause an anti-bacterial or anti-microbial effect on them). These properties are also changeable if we alter the morphological features of the NPs. Studies have shown improvement in microbiological reaction rates by using magnetic nanoparticles. However, nanoparticle toxicity is the major area of concern, as it can decrease therapeutic efficiency and cause adverse effects. Considering the wide range of responses and their reasons, this review summarizes the effects an iron oxide nanoparticle can have on the bacterial cell in general, the factors that influence those effects, and the relation of NP's characteristics to their significant differences in effects on bacteria.
Nanotechnology Reviews, 2018
Nanoparticles are considered magic bullets because of their unique properties. Nowadays, the use ... more Nanoparticles are considered magic bullets because of their unique properties. Nowadays, the use of nanoparticles has emerged in almost every field of science and technology, owing to its potential of revolutionizing specific fields. In the field of food science and technology, the use of nanoparticles is being studied in diverse areas, starting with the harvesting of crops up to final food consumption. With the increased usage of nanoparticles in day-today life, concern over their safety has arisen in everyone's mind. There is an imbalance between the increase in research to identify new nanoparticle applications and their safety, and this has triggered pressure on scientists to identify the possible effects of nanoparticles on human health. There are numerous studies on the use of nanotechnology in food and the effect of nanoparticles on human health, but there is a vacuum in the literature in terms of the combined analysis of such studies. This review is an attempt to present and analyze different studies on the use and the safety of nanoparticles in food.
International Journal of Engineering Research & Technology, 2025
Multidrug resistance mediated by ATP-binding cassette transporters remains a critical barrier to ... more Multidrug resistance mediated by ATP-binding cassette transporters remains a critical barrier to effective cancer chemotherapy, driving tumor recurrence and treatment failure. This review comprehensively examines innovative multifunctional nanoparticle strategies designed to overcome transporter-mediated efflux mechanisms. We analyze nanocarrier platforms enabling targeted co-delivery of chemotherapeutics with transporter inhibitors, gene-silencing approaches suppressing efflux pump expression, and stimuli-responsive systems exploiting tumor microenvironment features. The work highlights emerging technologies including nanobots and AI-designed nanoparticles while addressing translational challenges like protein corona formation and manufacturing scalability. By synthesizing recent advances in nanomedicine, this review provides researchers with critical insights into next-generation approaches for combating drug-resistant cancers through rational nanomaterial engineering.
Journal of Advanced Research in Applied Chemistry and Chemical Engineering, 2016
The present study is about a novel reaction course to produce biodiesel. The effect of sonication... more The present study is about a novel reaction course to produce biodiesel. The effect of sonication treatment for enhancing the activity of enzymes, particularly dealing with transesterification reaction using lipase to produce Biodiesel [Fatty Acid Methyl Ester (FAME)], has also been studied. The normal batch time for these reactions without sonication treatment was 12 hours and hence, the reaction requires intensification. Therefore, sonication treatment is tried to intensify the process, which adds to the novelty of the current scheme for biodiesel synthesis.
Nutrition and Food Science International Journal, 2017
In recent years, several deaths have been reported due to diabetes worldwide and India is no exce... more In recent years, several deaths have been reported due to diabetes worldwide and India is no exception. A proper care of diet and constant medication is the only way to counter this disease presently. It is very difficult for a diabetic patient to keep a tab on his cumbersome diet plan and this has led to an enormous responsibility on scientists, particularly those related to food and nutrition, to look for solutions to this problem. High sugar or starch-containing foods are the target foods which diabetic patients cannot consume in a normal quantity. Actually, these foods have high glycemic index and increase the blood sugar level abruptly after their consumption and unfortunately, such foods are mostly staple like rice and wheat products and are an integral part of any diet throughout the world. In countries like India the consumption of rice and/or wheat is directly related to the satiety value of people and if someone skips rice or bread from his meals, he remains hungry psychologically. So, it is very difficult to have a control on the consumption of such foods. Incorporation of dietary fibre in such foods is one of the best solutions for this problem and market is providing consumers with a variety of such products. Dietary fibre has an ability to absorb the glucose in the small intestines and ensure a controlled release of this glucose into the bloodstream, thus, preventing the abrupt rise in blood glucose level. Both the demand and the variety of dietary fibre fortified foods are on the increase which is undoubtedly a positive sign. This mini-review presents the approaches presently being administered and researched to prevent and control diabetes including the role of different drugs and diet management.
Molecular Biology Reports
By the end of 2019, COVID-19 was reported in Wuhan city of China, and through human-human transmi... more By the end of 2019, COVID-19 was reported in Wuhan city of China, and through human-human transmission, this virus spread worldwide and became a pandemic. Initial symptoms of the disease include fever, cough, loss of smell, taste, and shortness of breath, but a decrease in the oxygen levels in the body leads, and pneumonia may ultimately lead to the patient's death. However, the symptoms vary from patient to patient. To understand COVID-19 disease pathogenesis, researchers have tried to understand the cellular pathways that could be targeted to suppress viral replication. Thus, this article reviews the markers that could be targeted to inhibit viral replication by inhibiting the translational initiation complex/regulatory kinases and upregulating host autophagic flux that may lead to a reduction in the viral load. The article also highlights that mTOR inhibitors may act as potential inhibitors of viral replication. mTOR inhibitors such as metformin may inhibit the interaction of SARS-CoV-2 Nsp's and ORFs with mTORC1, LARP1, and 4E-BP. They may also increase autophagic flux by decreasing protein degradation via inhibition of Skp2, further promoting viral cell death. These events result in cell cycle arrest at G1 by p27, ultimately causing cell death.
Polyhydroxybutyrate biosynthesis from different waste materials, degradation, and analytic methods: a short review
Polymer Bulletin, Jul 28, 2022
Journal of Pharmacognosy and Phytochemistry, 2019
Seeds of three different varieties of maize (HQPM-1, HQPM-7 and BIO-9681) were obtained from IARI... more Seeds of three different varieties of maize (HQPM-1, HQPM-7 and BIO-9681) were obtained from IARI, New Delhi. After thorough cleaning and grading the maize seeds were well dried before storage and treated with synthetic polymer @ 9 ml per kg of seed, biocide (Neem oil @ 10ml / kg) and fungicide (Carbendazim) 12% @ 2.5 g/kg. Seeds were stored for 3, 6, 9, 12, 15 and 18 months respectively under ambient condition. The results revealed that, the seed treatment with polymer @ 9 ml + Neem oil @ 10 ml/ kg of seed observed significant maximum germination percentage, shoot length, root length, seedling length and higher vigor index. Seeds stored in cloth bag recorded significantly maximum seed quality parameters compared to plastic bag.
International Journal of Current Microbiology and Applied Sciences
Nanotechnology in sustainable agriculture: studies from seed priming to post-harvest management
Nanotechnology for Environmental Engineering
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Papers by Soban Ahmad Faridi