Papers by Juan Alvarez Carriles
Acta Neurologica Scandinavica, 2019
The estimated global prevalence of generalized tonic-clonic seizures (GTCS) is around 4.33 per 10... more The estimated global prevalence of generalized tonic-clonic seizures (GTCS) is around 4.33 per 1000 persons, although a great variability has been reported depending on the study and country. 1 The clinical burden of uncontrolled GTCS is significant, with higher morbidity and mortality rate than other seizure types. 2 Patients with GTCS are at a high risk of accidents and injury, 3 as well as at increased risk related to epilepsy (SUDEP). 4 SUDEP is the sudden, unexpected, witnessed or unwitnessed, non-traumatic and non-drowning death in patients with epilepsy, with or without evidence of a seizure, and excluding documented status epilepticus, in which autopsy does not reveal an anatomic or toxicological cause of death. 5 SUDEP is the second most common cause of lost adult life years after stroke, with an estimated incidence of 1.2 deaths per 1000 individuals with epilepsy, 6 and the presence of GTCS rates as the highest risk factor,
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[Functional reorganization of language in a case of cortical development disorder with continuous spike and wave during sleep]
Neurología (Barcelona, Spain), 2006
Left cerebral hemisphere dominance for language is a well known fact. However, this typical later... more Left cerebral hemisphere dominance for language is a well known fact. However, this typical lateralization may be affected when left hemisphere is damaged at an early age. In this case, neuronal plasticity allows language to be totally or partially transferred to another area within the ipsilateral or contralateral hemisphere. 21 year old woman. Congenital right hemiparesis. Focal epilepsy and continuous spike and wave during NREM sleep at 4 years old. Magnetic resonance imaging: extensive malformation of cortical development in the left hemisphere. From 7 years old, seizures were controlled and the continuous spike and wave discharges disappeared. Valproic acid, 500 mg/day. Neuropsychological assessment showed that basic language functions were well preserved, while there were signs of non-dominant hemisphere dysfunction. These paradoxical results, together with the fact that the patient was left-handed, established the possibility of functional reorganization of language to the ri...
[Rivastigmine in a case of autopsy proved frontotemporal dementia (Pick's disease)]
Revista de neurologia
Cholinesterase inhibitors are useful in the treatment of behavioural and psychological symptoms i... more Cholinesterase inhibitors are useful in the treatment of behavioural and psychological symptoms in Alzheimer's disease. Their effectiveness in frontotemporal dementia has not been proved, since such a claim has only been backed by the publication of one open-label trial in which the behavioural and psychological symptoms of the patients treated with rivastigmine over a 12-month period improved significantly with respect to those belonging to a group that were given a placebo. We report a case of frontotemporal dementia, Pick's disease, which improved with rivastigmine treatment. A 61-year-old male who presented a progressive clinical picture of behavioural disorders and executive-cognitive impairment that had begun two years earlier. Magnetic resonance imaging of the head revealed severe frontotemporal atrophy. Neuropsychological Inventory (NPI). Overall score 36/144 (6/12: anxiety, disinhibition and aberrant motor behaviour, 4/12: agitation, irritability and apathy; 3/12: s...
[Functional reorganization of language in a case of cortical development disorder with continuous spike and wave during sleep]
Neurología (Barcelona, Spain), 2006
Left cerebral hemisphere dominance for language is a well known fact. However, this typical later... more Left cerebral hemisphere dominance for language is a well known fact. However, this typical lateralization may be affected when left hemisphere is damaged at an early age. In this case, neuronal plasticity allows language to be totally or partially transferred to another area within the ipsilateral or contralateral hemisphere. 21 year old woman. Congenital right hemiparesis. Focal epilepsy and continuous spike and wave during NREM sleep at 4 years old. Magnetic resonance imaging: extensive malformation of cortical development in the left hemisphere. From 7 years old, seizures were controlled and the continuous spike and wave discharges disappeared. Valproic acid, 500 mg/day. Neuropsychological assessment showed that basic language functions were well preserved, while there were signs of non-dominant hemisphere dysfunction. These paradoxical results, together with the fact that the patient was left-handed, established the possibility of functional reorganization of language to the ri...
[Neuropsychological implications of Crouzon syndrome: a case report]
Revista de neurologia
Crouzon syndrome (CS) has traditionally been associated with moderated mental retardation. Howeve... more Crouzon syndrome (CS) has traditionally been associated with moderated mental retardation. However, very few studies have quantified in these patients the degree of this mental retardation, and even less research has been carried out to evidenciate the typical neuropsychological profile, including affective, cognitive and executive functions. We present a single case-study of a 16 year-old, right-handed female affected of CS. Neuropsychological functions assessed included attention, concentration, memory, visual perception, language, arithmetic processes, praxis, executive functions, reasoning and general intelligence. Deficient results have been obtained in learning and memory, attention, language, graphic praxis, comprehension of social situations and executive functions (frontal lobes). Nevertheless, the patient kept within normal limits her spatial and temporal orientation, visual perception, visual-spatial and manipulative abilities and arithmetic processes. Results suggest tha...
Neuropsychological performance of patients in treatment for cocaine addiction / Rendimiento neuropsicológico de pacientes en tratamiento por adicción a la cocaína
Health and Addictions Salud Y Drogas, Oct 21, 2008
Reorganización funcional del lenguaje en un caso de trastorno del desarrollo cortical con punta onda continua durante el sueño
Neurologia Publicacion Oficial De La Sociedad Espanola De Neurologia, 2006
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Revista De Psicologia General Y Aplicada Revista De La Federacion Espanola De Asociaciones De Psicologia, 2002
Rendimiento neuropsicológico de pacientes en tratamiento por adicción a la cocaína
Salud Y Drogas, 2008
... prueba de fluidez verbal que requiere un adecuado funcio-namiento de la memoria de trabajo y ... more ... prueba de fluidez verbal que requiere un adecuado funcio-namiento de la memoria de trabajo y de las funciones ejecutivas, como la ... 5. DISCUSIÓN ... En concreto, el grupo clí- nico obtuvo un rendimiento menor en tareas relacionadas con el procesa-miento de información e ...
Neuropsicología y epilepsia
Manual De Neuropsicologia 2008 Isbn 978 84 85424 71 9 Pags 339 362, 2008
Información del artículo Neuropsicología y epilepsia.
We reported the case of a female patient with chorea and cognitive disorders due to Wilson's ... more We reported the case of a female patient with chorea and cognitive disorders due to Wilson's disease with cerebral and hepatic involvement. Under treatment with D-penicillamine and zinc salts she initially evidenced worsening of the motor function, with congitive stability. After adjustment of the D-penicillamine Schedule both processe improved, with a more favourable course for the superior functions.
Neurology, Jan 1, 2009
Background: Due to the high prevalence of mild cognitive impairment (MCI) and dementia in Parkins... more Background: Due to the high prevalence of mild cognitive impairment (MCI) and dementia in Parkinson disease (PD), routine cognitive screening is important for the optimal management of patients with PD. The Montreal Cognitive Assessment (MoCA) is more sensitive than the commonly used Mini-Mental State Examination (MMSE) in detecting MCI and dementia in patients without PD, but its validity in PD has not been established.
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Papers by Juan Alvarez Carriles