Papers by Gabrielli Algazal Marin
São Paulo Medical Journal, 2021
Background: Traumatic brain injury (TBI) is the main cause of death among individuals between 1 a... more Background: Traumatic brain injury (TBI) is the main cause of death among individuals between 1 and 44 years of age, and severe TBI is associated with a mortality rate between 30% and 70%. In this context, randomized clinical trials have studied medications to reduce morbidity in severe TBI, one of which is Amantadine. This drug acts on the increase of extracellular dopamine and as an NMDA antagonist. Objectives: Developing a systematic review of systematic reviews to evaluate the efficacy of Amantadine in reducing morbidity in patients with severe TBI. Methodology: The search was conducted in the PubMed, Embase, Cochrane Library, and Portal Regional BVS databases. Results: Eleven systematic reviews were included. The literature review of 7 articles demonstrated the efficacy of treatment with Amantadine in the following clinical aspects after TBI: aggression, irritability, agitation, mood, and attention deficit. On the other hand, one article did not consider the use of Amantadine s...
Journal of Neurology & Stroke, 2021
Introduction: Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2) was first detected in ... more Introduction: Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2) was first detected in December 2019 in the city of Wuhan, China, and has since taken on worldwide proportions. It is known that individuals with Coronavirus disease-19 (COVID-19) have systemic clinical manifestations. Among the multisystemic effects, cerebral venous thrombosis (CVT) is responsible for high mortality rates. In this sense, understanding the association between CVT and SARS-CoV-2 infection directly impacts the disease's morbidity and mortality. Methodology: Literature review in the PubMed and Embase databases, with the following search terms: “COVID-19”, “SARS-CoV-2”, “Venous thromboembolism”, “Thrombosis”, “Cerebral Venous Thrombosis”, “Intracranial Sinus Thrombosis” and “Cranial Sinus Thrombosis”. The selected articles were written in English, which addressed the various aspects of COVID-19. Results and discussion: CVT are a rare complication of COVID-19, with an incidence between 0.02 to ...
InterAmerican Journal of Medicine and Health, 2021
Introdução: Em 2019 e 2020 o mundo foi afetado pela pandemia da coronavírus (COVID-19) - uma emer... more Introdução: Em 2019 e 2020 o mundo foi afetado pela pandemia da coronavírus (COVID-19) - uma emergência de saúde pública, conforme a Organização Mundial da Saúde (OMS). A resposta ao aumento no número de infecções e mortes foi o fechamento de diversos ambientes e a imposição do distanciamento social, fato que alterou os locais de interação e vivência dos estudantes universitários. Objetivos: Evidenciar e compreender os reflexos psicossociais, especialmente a depressão, em virtude da doença e do cenário pandêmico. Métodos: Trata-se de revisão literária narrativa. Foram encontrados 234 artigos, na base dados PUBMED e PubMed Central com as palavras-chave “students”; “depression”; “quarantine”; “coronavirus infections”. Foram excluídos artigos que não trataram de depressão, estudantes ou que não abordavam estudantes universitários ou não diferenciaram as populações no estudo, restando 14 artigos. Resultados: Foram observados diversos impactos na vida dos estudantes universitários, como ...
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Papers by Gabrielli Algazal Marin