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All Journal MNJ (Malang Neurology Journal) Jurnal Pengabdian Masyarakat: Humanity and Medicine Neurona
Harun, Yusril
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Dentistry Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

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Peningkatan pemahaman pegawai PT. Semen Baturaja cabang Palembang tentang demensia dan pengenalan metode deteksi penurunan fungsi kognitif pada anggota keluarga Nindela, Rini; Harun, Yusril; Marisidina, Selly; Handayani, Sri
Jurnal Pengabdian Masyarakat: Humanity and Medicine Vol 2 No 2 (2021): Jurnal Pengabdian Masyarakat: Humanity and Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/Hummed.V2I2.48

Abstract

Dementia is a decrease in cognitive function which is quite severe compared to before, so that it interferes with social and professional activities in daily living. Complaints of cognitive decline are often not recognized by the patients themselves. They are often recognized as part of the normal aging process and not sufficient reason to seek treatment. This community service activity in the form of an online seminar aims to provide education to the community about cognitive function and dementia and how to detect it in family members or closest people. The target of this activity is the employees of PT. Semen Baturaja aged 30-50 years as many as 28 people. Evaluation of this activity is carried out by asking participants to fill in a list of questions before and after the seminar via Google Form. Data regarding the level of understanding of the participants is presented descriptively in the form of a diagram. After participating in this activity the participants became more aware that dementia is not a normal condition but a disease that needs to be examined and treated by a doctor. Thus, it can be concluded that this activity is quite effective in increasing public understanding and attitudes about dementia.
THE RELATIONSHIP OF THE CHARACTERISTICS OF ANTI-EPILEPSY DRUGS WITH THE C OGNITIVE FUNCTION OF EPILEPSY PATIENTS Handayani, Sri; Partan, Radiyati Umi; Hafy, Zen; Octaviana, Fitri; Harun, Yusril; Bahar, Erial; Lestari, Nova
MNJ (Malang Neurology Journal) Vol. 11 No. 2 (2025): July
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2025.011.02.02

Abstract

Background: One of the side effects of the use of antiepileptic drugs (AEDs) is cognitive disorder. Several studies show a relationship between the type of AEDs and cognitive disturbance in people with epilepsy. Dose-dependent side effects of AEDs have also been reported in prior research. However, there are results from different studies on different populations. Objective: This research aims to evaluate the relationship between AEDs characteristics and the cognitive function of epilepsy patients. Methods: This cross-sectional study was conducted in the Neurology Department of Dr. Mohammad Hoesin General Hospital Palembang, from 1 November 2021 to 31 March 2022. Researchers used the MoCA-Ina questionnaire to collect medical record data and conduct interviews. Results: In this research, the number of research subjects obtained was 70 people with epilepsy. Characteristics of sociodemographic sufferer Epilepsy in this study was mostly (44.3%) aged 26 – 45 years with type sex most were women (71.4%), and the majority subjects (52.9%) had level high school education. Characteristics of antiepileptic drugs consumed by people living with epilepsy: most of them, i.e., amounting to 57.1%, have consumed antiepileptic drugs for > 12 months. Most of the research subjects (64.3%) had function-impaired cognitive range MoCA-Ina scores of 8 – 30. The function most cognitively disturbed, namely in the memory domain, cancels that am, counting to 82.9%. Education level is the only variable from characteristics of sociodemographic and clinical features connected significantly to cognitive function in general (p-value 0.013). The number, duration, and type of antiepileptic drugs do not determine a significant relationship with cognitive function in general. Conclusion: There is a significant relationship between valproic acid and the number of AEDs with the naming domain, as well as between valproic acid and the duration of AEDs with the abstraction domain.
Gambaran Quantitative Electroencephalography Pada Penderita Gangguan Kognitif Pascastroke di RSUP Dr. Mohammad Hoesin Palembang Febrianto, Yohanes; Nindela, Rini; Harun, Yusril; Handayani, Sri; Legiran, Legiran
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 40 No 3 (2024): Volume 40, No 3 - Juni 2024
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v40i3.573

Abstract

Post-stroke cognitive impairment (PSCI) is one of the post-stroke complications that is often overlooked. Quantitative electroencephalography (QEEG) is an alternative examination in patients with PSCI. QEEG results of PSCI patients shows abnormalities in spectral power, coherence, power ratio, and peak alpha frequency (PAF). Aim: Knowing the QEEG characteristic in PSCI patients and the characteristic differences between the post stroke dementia (PSD) and post stroke cognitive impairment no dementia (PSCI-ND). This research is a descriptive study of PSCI patients at the RSMH Palembang from September-November 2023, followed by a QEEG examination. There were 31 patients who completed the research. There is higher median absolute and relative power delta and theta both per region and globally, decreased interhemsiferous coherence at F3-F4, P3-P4, O1-O2, T5-T6, C3-C4, increased delta alpha ratio and delta theta alpha beta ratio in the frontal region, as well as a decrease in peak alpha frequency in all regions. Patients with post-stroke dementia have more abnormality in relative global power, frontal DAR and DTABR, and PAF than patients with PSCI-ND Stroke can cause slowed conduction along the cortical-subcortical pathways, disruption of cholinergic pathways and impaired communication in various parts of the brain. This condition can cause a decrease in alpha power as an important wave in cognitive function and an increase in delta power in various brain regions. A decrease in the fast wave spectrum and an increase in the slow wave spectrum may lead to decreased cognitive function as seen in patients with PSCI Post stroke cognitive impairement, Power ratio, Quantitative electroencephalography, spectral power.
Co-Authors Erial Bahar, Erial Febrianto, Yohanes Fitri Octaviana Handayani, Sri Legiran Legiran Marisidina, Selly Nova Lestari Radiyati Umi Partan, Radiyati Umi Rini Nindela, Rini Zen Hafy