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Figure 1: Graph of absorbance vs concentration for Aspirin tends to 1 in both diffusion and permeation study, then it was assured and can be assumed that diffusion inside the body and even the permeation rate will be in the steady state range throughout the day. (figures 2 & 3, tables 1 & 2).

Figure 1 Graph of absorbance vs concentration for Aspirin tends to 1 in both diffusion and permeation study, then it was assured and can be assumed that diffusion inside the body and even the permeation rate will be in the steady state range throughout the day. (figures 2 & 3, tables 1 & 2).

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Releasing of Chorioalantoic membrane performed after removing the albumin and globulin portion of the egg, Then dipped it in the solution of HCl : Water 1:4. Now after washing it transdermal Patch inserted inside it and tied with thread. It has been kept under stirring in Phosphate buffer for an hour.” Here the Aspirin Patch is using which is having analgesic as well as antiplatelet action. The main action of this aspirin is due to the inhibition cyclooxygenase pathway, this drug basically inhibit Coxl and Cox2 by blocking thromboxane residue after acetylating serine residue.’ So for doing this sort of medication there was a need to carry out a diffusion and permeation study. For doing the permeation study chorioalantoic membrane of egg has been selected and it shows a good permeability for this and also shows good diffusion result also.°
Releasing of Chorioalantoic membrane performed after removing the albumin and globulin portion of the egg, Then dipped it in the solution of HCl : Water 1:4. Now after washing it transdermal Patch inserted inside it and tied with thread. It has been kept under stirring in Phosphate buffer for an hour.” Here the Aspirin Patch is using which is having analgesic as well as antiplatelet action. The main action of this aspirin is due to the inhibition cyclooxygenase pathway, this drug basically inhibit Coxl and Cox2 by blocking thromboxane residue after acetylating serine residue.’ So for doing this sort of medication there was a need to carry out a diffusion and permeation study. For doing the permeation study chorioalantoic membrane of egg has been selected and it shows a good permeability for this and also shows good diffusion result also.°
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PharmacologyMaterials SciencePharmacyPharmaceutical TechnologyRegulatory AffairsPharmaceutics and Drug DeliveryICH/GCP
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