Phytochemical Screening of Calendula Officinalis Linn

Pharmacognosy reviews, 2013

This review includes 84 references on the genus Calendula (Asteraceae) and comprises ethnopharmacology, morphology and microscopy, phytoconstituents, pharmacological reports, clinical studies and toxicology of the prominent species of Calendula. Triterpene alcohols, triterpene saponins, flavonoids, carotenoids and polysaccharides constitute major classes of phytoconstituents of the genus. A few species of this genus have medicinal value, among these Calendula officinalis Linn., has been traditionally used in the treatment of various skin tumors, dermatological lesions, ulcers, swellings and nervous disorders as well as almost 200 cosmetic formulations, i.e., creams, lotions, shampoos. Despite a long tradition of use of some species, the genus has not been explored properly. In the concluding part, the future scope of Calendula species has been emphasized with a view to establish their multifarious biological activities and mode of action.

Revista de Chimie

The marigold extracts are used in traditional medicine for its anti-inflammatory, decongestive, antiseptic, antifungal, antimicrobial and immunostimulating properties. Existing studies have partially proved these properties, but are incomplete with regard to the possibility of standardizing the extract using the best working conditions so as it to be included in dietary supplements. The purpose of this study is to investigate the chemical composition of the marigold extracts, their contents in flavonoids and polyphenolic compounds, as well as to determine the contents in oligoelements of the plant material through the ICP-OES method. Based on the results of this study we conclude that a complete extraction may be accomplished after lyophilizing the solution of hydroalcoholic extract, followed by extraction in acid medium so as to permit a better assessment of the bioactive compounds.

Journal of Biological and Scientific Opinion, 2023

Ayurveda is the ancient thought and treatise that deals with the knowledge of living a healthy life. There are several types of medicaments that are being used in the Ayurvedic mode of treatment. The source of these drugs is diverse and belongs to different category. The category ranges from plants and animals to minerals and encircles around different types of species of plants and animals with vivid habitats. Ayurvedic plants have shown their effects on various kind of diseases. Those properties of the plants are sublimed in some molecules in the plants, which can be extracted out by performing various kind of processes (eg. Soxhlation, Percolation). Many plants which are used by the human being in daily life, also have some effects in curing some disease conditions. Calendula officinalis is a plant that possess many pharmacological actions due to it contains numerous polyphenols & antioxidants, so this plant is studied both in the laboratory as well as in clinical setting for different therapeutic aspects. This review makes a humble effort to summaries & gather knowledge about the Description, Identification & Pharmacological Properties of the said plant. The study shows that this plant not only possessed wound healing properties, but also it has a wide range of pharmacological uses. Furthermore experiments & clinical trials needed to confirm those founded results.

Revista Colombiana de Biotecnología

In this work, different bioactive compounds were obtained from Calendula officinalis by using conventional soxhlet extraction, shaker-assisted extraction and ultrasound-assisted extraction. The effect of different extraction time and temperature on the quantity of bioactive compounds obtained was investigated. The extracts obtained were further analyzed by UV–visible spectrometric analysis. The effect of extraction technique on both the colorant power of carotenoids and antibacterial capacity of the flavonoids was evaluate. Colorant power was evaluated by UV–visible spectrometric and dyeing ability in dairy product. Antibacterial activity of extracts was developed against Escherichia coli and Salmonella typhimurium by diffusion technique in well. Outstanding extraction results were obtained by ultrasound extraction technique performed during 2 hours, at 30°C and with 96% ethanol, for bioactive compounds evaluated. The same treatment showed the best result in colorant power and dyein...

Phytotherapy has established a therapeutic medicinal model that has exponentially been increasing over the years. Plants secondary metabolites stand out in the field of pharmacology, as a result of its biological effects in man. This study discusses about the pharmacological effects of Calendula officinalis at different researches, given that this contribution is important among researchers and the entire market, aiming at the therapeutic advancement. Calendula officinalis showed high therapeutic efficacy when applied in healing, anti-inflammatory and antisepitic processes due to its bioactive compounds.

Natural Product Communications, 2016

Pot Marigold (Calendula officinalis L.) is an annual ornamental plant with yellow to orange flowers which belongs the the Asteraceae family, its flowers are used in the pharmaceutical, cosmetic and food industries. The commercial samples of seeds (n=24) of C officinalis were cultivated in home gardens in Estonia. Total carotenoid contents, determined spectrophotometrically (λ=455 nm) in the inflorescences, varied from 0.7 to 2.7%, the cultivar with the highest carotenoid content was ‘Dracon’. The total content of flavonoids, determined spectrophotometrically (λ=370 nm), varied from 0.8% to 1.7%. The best cultivar contained almost maximum amount of total carotenoids (2.5%) and flavonoids (1.7%) was ‘Radio”. The oil yields of eight cultivars of C officinalis obtained were from 0.10 to 0.43%, the highest yield (0.43%) of the oil was obtained from the cultivar ‘Double Ball’. A total 70 compounds were identified and analysed by GC-MS in the essential oil of C officinalis, representing ov...

Natural Product Research, 2011

Full terms and conditions of use: http://www.informaworld.com/terms-and-conditions-of-access.pdf This article may be used for research, teaching and private study purposes. Any substantial or systematic reproduction, redistribution , reselling , loan or sub-licensing, systematic supply or distribution in any form to anyone is expressly forbidden. The publisher does not give any warranty express or implied or make any representation that the contents will be complete or accurate or up to date. The accuracy of any instructions, formulae and drug doses should be independently verified with primary sources. The publisher shall not be liable for any loss, actions, claims, proceedings, demand or costs or damages whatsoever or howsoever caused arising directly or indirectly in connection with or arising out of the use of this material.

Savremene tehnologije, 2014

The content of total phenols, flavonoids and antioxidant activities of different plant extracts of Callendula Officinalis L., used in Serbian traditional medicine were determined. The phenol content was determined by using UV-Vis measurements at 765 nm in the tested plant extracts obtained by standard extraction of Calendula officinalis L. The tested extracts, examined by DPPH method showed a high antioxidant activity that correlated significantly with the content of phenols and flavonoids. All tested extracts exhibited a strong scavenging activity against DPPH radicals (more than 96,8%). The contents of metals (Zn, Fe, Cu, Mn, Cd, Cr, and Pb) were determined by the flame atomic absorption spectrometer. Toxic metals, such as Cd, Cr, and Pb were not detected in the studied plant materials. The content of other metals in the plants and their extracts were low, except for iron. We examined the correlation of metals (Zn, Fe, Cu, Mn) and the phenolic compounds content in the extracts. The studied plants from the Southeast Serbia are suitable for the preparation of teas and herbal extracts due to the low content of toxic metals (Zn, Fe, Cu, and Mn), a high content of phenolic compounds and a high antioxidant activity.

Revista Brasileira de Ciências Farmacêuticas, 2008

Terpenes and aroma volatiles from flowers of Calendula officinalis cultivated in southeastern Brazil were obtained by steam distillation (SD), headspace-cold finger (HS-CF) extraction and headspace solid-phase microextraction (HS-SPME) coupled with gas chromatography and mass spectrometric analysis. The dried flowers contained 0.1% oil. Kovats indices and mass spectra were used to identify 27 individual components in the various volatile fractions. The main components present in the volatile fractions of the C. officinalis flowers, obtained by SD, HS-SPME, and HS-CF, were δ-cadinene (22.5, 22.1, and 18.4 %) and γ-cadinene (8.9, 25.4, and 24.9 %) while 20.4 % of α-cadinol was seen only after SD extraction.

Chromatographia, 2011

The variation in the content and composition of Calendula officinalis essential oils was studied using supercritical CO2 extraction followed by GC–MS. Samples of marigold were harvested at four different vegetation stages. A total of 43 different compounds were identified in the essential oils. The identified components were represented mainly by monoterpenes, sesquiterpenes and sesquiterpene alcohols. The qualitative and quantitative composition of the essential oils of C. officinalis varied during the studied vegetation stages. To determine the significance of changes in the identified compounds, to classify the obtained plant samples into groups and to find the similarity measure between them, several statistical data mining techniques were applied, namely hypothesis testing, principal component analysis and hierarchical cluster analysis. α-Thujene, α-pinene, γ-cadinene and δ-cadinene were predominant in all vegetation phases. Development of buds and the end of the flowering stages were distinguished by the highest content of essential oils, while full-flowering stage was distinguished by sesquiterpenols (1,10-di-epi-cubenol, 1-epi-cubenol, τ- and α-cadinols, β-selinelol constituted 11.6% of the oils).