Space, time and consciousness
2003, Journal of Consciousness Studies
Abstract
This paper presents a potential mechanism for the conscious brain to anticipate impending opportunities and threats to survival through massively parallel weak quantum measurement (MPWQM) induced by the combined effects of edge of chaos sensitivity and phase coherence sampling of brain states. It concludes that the underpinnings of this process emerged in single-celled eucaryotes in association with (a) excitability-induced sensitivity to electro-chemical perturbations in the milieu as an anticipatory sense organ and (b) cell-to-cell signaling necessary for critical phases in the life cycle. This gives rise to watershed implications for the capacity of conscious experience to anticipate impending events in direct ways which complement computation based on past experiences and implies that conscious intentionality or 'free-will' may have physical influences beyond the raw application of the brain to an organism's immediate behavior.
Key takeaways
AI
AI
- Consciousness may arise from massively parallel weak quantum measurement (MPWQM) and edge-of-chaos dynamics.
- The paper explores how consciousness evolved from single-celled eukaryotes to anticipate survival threats.
- Neuroscience cannot fully explain subjective consciousness due to the 'hard problem' of correlating mind and brain.
- Edge of chaos processing allows vertebrate brains to resolve computationally intractable survival dilemmas in real-time.
- Free will may coexist with quantum uncertainty, challenging deterministic views of human behavior.
References (241)
- Aaronson S (2013) host in the Quantum Turing Machine ArXiv:1306.0159.
- Aharonov Y., Albert D.Z. , Vaidman L. (1988) How the Result of a Measurement of a Component of the Spin of a Spin-2 Particle Can Turn Out to be 100 Physical review letters 60, 1351.
- Aharonov Y, Colombo F, Popescu S, Sabadini I, Struppa D, J (2014) The quantum pigeonhole principle and the nature of quantum correlations http://arxiv.org/pdf/1407.3194v1
- Alkire M, Hudetz A., Tononi G. (2008) Consciousness and Anesthesia Science 322/5903 876-880.
- Allman J. et al. (2011) The von Economo neurons in the frontoinsular and anterior cingulate cortex Ann. N.Y. Acad. Sci. 1225 59-71
- Amit G. (2012) 'Eye bath' to thank for quantum vision in birds New Scientist http://www.newscientist.com/article/dn22199-eye-bath-to-thank-for-quantum-vision-in-birds.html
- Ananthaswamy A. (2009) 'Consciousness signature' discovered spanning the brain New Scientist 17 March. http://www.newscientist.com/article/dn16775-consciousness-signature-discovered-spanning-the-brain.html
- Ananthaswamy A. (2009) Whole brain is in the grip of consciousness New Scientist 18 March. http://www.newscientist.com/article/mg20127004.300-whole-brain-is-in-the-grip-of-consciousness.html
- Ananthaswamy A. (2010) Firing on all neurons: Where consciousness comes from New Scientist 22 March. http://www.newscientist.com/article/mg20527520.400-firing-on-all-neurons-where-consciousness-comes- from.html Ananthaswamy A (2012) Photon reaches from beyond the grave in quantum trick New Scientist 4 Oct.
- Ananthaswamy A. (2013) The self: Trick yourself into an out-of-body experience New Scientist 20 Feb.
- Anjard C., Loomis W. (2006) GABA induces terminal differentiation of Dictyostelium through a GABAB receptor Development 133 2253-2261 doi:10.1242/dev.02399
- Azmitia E. C. (2010) Evolution of Serotonin: Sunlight to Suicide Muller C & Jacobs B (Eds.) Handbook of Behavioral Neurobiology of Serotonin Elsevier ISBN 978-0-12-374634-4 DOI: 10.1016/B978-0-12-374634- 4.00034-4
- Baars, B. J. (1997) In the Theatre of Consciousness: Global Workspace Theory, A Rigorous Scientific Theory of Consciousness. Journal of Consciousness Studies, 4/4 292-309 8
- Baars, B. J. (2001) In the Theater of Consciousness Oxford University Press US.
- Bahrami B., Olsen K., Latham P., Roepstorff A., Rees G., Frith C. (2010) Optimally Interacting Minds Science 329/5995 1081-5.
- Barras C (2013) Mind maths: The sum of consciousness New Scientist 6 February. http://www.newscientist.com/article/mg21729032.400-mind-maths-the-sum-of-consciousness.html
- Barron, A. B., Maleszka, R., Vander Meer, R. K., & Robinson, G. E. (2007). Octopamine modulates honey bee dance behavior. Proceedings of the National Academy of Sciences, 104(5), 1703-1707. DOI:10.1073/pnas.0610506104. PMC 1779631.
- Barrow J, Tipler F (1988) The Anthropic Cosmological Principle, Oxf. Univ. Pr., Oxford.
- Basar E., Basar-Eroglu J., Röschke J., Schütt A., (1989) The EEG is a quasi-deterministic signal anticipating sensory-cognitive tasks, in Basar E., Bullock T.H. eds. Brain Dynamics Springer-Verlag, 43-71.
- Basar E, Basar-Erogluc C, Karakas S, Schürmann M (2001) Gamma, alpha, delta, and theta oscillations govern cognitive processes International Journal of Psychophysiology 39 241-8.
- Baskar, Mani & Hyde (2021) Serotonin and MAOA enable the organizer and tip dominance in Dictyostelium Research Square doi:10.21203/rs.3.rs-150066/v1.
- Baumeister R et al. (2009) Prosocial Benefits of Feeling Free: Disbelief in Free Will Increases Aggression and Reduces Helpfulness Personality and Social Psychology Bulletin 35 260.
- Bear A & Bloom P (2016) A Simple Task Uncovers a Postdictive Illusion of Choice Psychological Science 27/6 914-922.
- Bell J.S. (1966) On the Problem of Hidden Variables in Quantum Mechanics Rev. Mod. Phys. 38/3, 447.
- Bem D (2011) Feeling the Future: Experimental Evidence for Anomalous Retroactive Influences on Cognition and Affect Journal of Personality and Social Psychology doi:10.1037/a0021524.
- Blenau W & Thamm M (2011) Distribution of serotonin (5-HT) and its receptors in the insect brain with focus on the mushroom bodies. Lessons from Drosophila melanogaster and Apis mellifera Arthropod Structure & Development 40 381-394.
- Bohm D. (1952) A suggested interpretation of the quantum theory in terms of 'hidden' variables I & II Phys. Rev. 85 166-93.
- Bor D (2013) Consciousness: Watching your mind in action New Scientist 20 May. Brooks M (2012) Reality: How does consciousness fit in? New Scientist 3 October.
- Brizzi G & Blum J (1970) Effect of growth conditions on serotonin content of Tetrahymena pyriformis Journal of Eukaryotic Microbiology (J. Protozool.) 17/4 553-555.
- Buckle H (1864) History of Civilization in England London Longmans Green. http://www.gutenberg.org/ebooks/author/42798
- Buckner R. et al. (2008) The brain's default network anatomy, function, and relevance to disease Ann. N.Y. Acad. Sci. 1124 1-38 doi: 10.1196/annals.1440.011.
- Buznikov, G. A., Lambert, W. H., & Lauder, J. M. (2001). Serotonin and serotonin-like substances as regulators of early embryogenesis and morphogenesis. Cell and tissue research, 305(2), 177-186. DOI10.1007/s004410100408
- Buznikov, G. A., Lambert, W. H., & Lauder, J. M. (2001). Serotonin and serotonin-like substances as regulators of early embryogenesis and morphogenesis. Cell and tissue research, 305(2), 177-186.
- Castelvecchi D. (2015) Quantum technology probes ultimate limits of vision Nature doi:10.1038/nature.2015.17731.
- Cauda F, et al. (2011) Functional anatomy of cortical areas characterized by Von Economo neurons Brain Struct Funct DOI:10.1007/s00429-012-0382-9.
- Cavanna A., Trimble M. (2006) The precuneus: a review of its functional anatomy and behavioural correlates Brain 129 564-583 doi:10.1093/brain/awl004.
- Chalmers, David (1996) The Conscious Mind: In Search of a Fundamental Theory Oxford University Press.
- Chaudhury S, Smith A, Anderson B, Ghose S, Jessen P (2009) Quantum signatures of chaos in a kicked top Nature 461 768-771.
- Chay T.R., Rinzel J. (1985), Bursting, beating and chaos in an excitable membrane model, Biophys. J. 47, 357- 366.
- Chen, G. Q., Cui, C., Mayer, M. L., & Gouaux, E. (1999). Functional characterization of a potassium-selective prokaryotic glutamate receptor. Nature, 402(6763), 817-821
- Cho A. (2011) Furtive Approach Rolls Back the Limits of Quantum Uncertainty Science 333 690-3.
- Clark C et al. (2014) Free to Punish: A Motivated Account of Free Will Belief Journal of Personality and Social Psychology 106/4 501-513.
- Coleman, J. R., Lindsley, D. B. (1975). Hippocampal electrical correlates of free behavior and behavior induced by stimulation of two hypothalamic-hippocampal systems in the cat. Experimental neurology, 49(2), 506-528.
- Conaco, C., Bassett, D. S., Zhou, H., Arcila, M. L., Degnan, S. M., Degnan, B. M., & Kosik, K. S. (2012). Functionalization of a protosynaptic gene expression network. Proceedings of the National Academy of Sciences, 109(Supplement 1), 10612-10618. doi/10.1073/pnas.1201890109.
- Conway JH and Kochen S (2006) The Free Will Theorem Foundations of Physics 36/10 doi: 10.1007/s10701-006- 9068-6.
- Conway JH and Kochen S (2009) The Strong Free Will Theorem Notices of the AMS 56/2 226-232.
- Cook G (2020) Does Consciousness Pervade the Universe? Philosopher Philip Goff answers questions about "panpsychism" Scientific American https://www.scientificamerican.com/article/does-consciousness-pervade- the-universe/
- Courtland R. (2011) Quantum states last longer in birds' eyes New Scientist http://www.newscientist.com/article/mg20927963.000-quantum-states-last-longer-in-birds-eyes.html
- Craig A. (2009) How do you feel -now? The anterior insula and human awareness Nature Rev. Neurosci 10 59- 70.
- Crick F, Koch C. (1992) The Problem of Consciousness Sci. Am. Sep. 110-117.
- Deacon T. (2012) Consciousness is a matter of constraint 30 November.
- Dehaene S., Changeux J.P. (2005) Ongoing spontaneous activity controls access to consciousness: A neuronal model for inattentional blindness. PLoS Biol 3(5) e141.
- Del Cul A., Baillet S., Dehaene S. (2007) Brain dynamics underlying the nonlinear threshold for access to consciousness. PLoS Biol 5(10) e260. doi:10.1371/journal.pbio.0050260
- Del Cul A., Dehaene S., Reyes P., Bravo E., Slachevsky A. (2009) Causal role of prefrontal cortex in the threshold for access to consciousness Brain 132 2531--2540.
- Demertzi et al. (2019) Human consciousness is supported by dynamic complex patterns of brain signal coordination Sci. Adv. 5 eaat7603 doi:10.1126/sciadv.aat7603.
- Dennett D. C. (1991) Consciousness Explained Little Brown & Co., Boston.
- Dennett D (2003) Freedom Evolves New York Viking.
- Dixon, P. B., Starling, D. J., Jordan, A. N., & Howell, J. C. (2009) Ultrasensitive beam deflection measurement via interferometric weak value amplification. Physical review letters, 102(17), 173601.
- Duane T, & Behrendt T (1965) Extrasensory electroencephalographic induction between identical twins Science 150/3694 367 doi:10.1126/science.150.3694.367.
- Dunn T. Spiders on drugs http://www.trinity.edu/jdunn/spiderdrugs.htm Dunne J. W. (1929) An Experiment with Time A & C Black, London https://archive.org/details/AnExperimentWithTime
- Eagleman, D. M., Sejnowski, T. J. (2000) Motion integration and postdiction in visual awareness. Science. 287/5460 2036-8.
- Eagleman, D.M., Sejnowski, T.J. (2000) Flash Lag Effect: Differential latency, not postdiction: Response. Science. 290/5494 1051a
- Eccles J. C. (1982) The Initiation of Voluntary Movements by the Supplementary Motor Area Arch Psychiatr Nervenkr 231 423-441.
- Eichinger, D., Coppi, A., Frederick, J., & Merali, S. (2002). Catecholamines in Entamoebae: Recent (re) discoveries. Journal of biosciences, 27(6), 589-593.
- Eichinger, L., Pachebat, J. A., Glöckner, G., Rajandream, M. A., Sucgang, R., Berriman, M., ... & Hauser, H. (2005). The genome of the social amoeba Dictyostelium discoideum. Nature, 435(7038), 43-57.
- Edwards, D.H., Kravitz, E.A. (1997) Serotonin, social status and aggression Curr. Opin. Neurobiol. 7 812-819.
- Emes, R. D., Pocklington, A. J., Anderson, C. N., Bayes, A., Collins, M. O., Vickers, C. A., ... & Grant, S. G. (2008). Evolutionary expansion and anatomical specialization of synapse proteome complexity. Nature neuroscience, 11(7), 799-806.
- Essman E (1987) The serotonergic system in Tetrahymena pyriformis International Journal of Clinical & Laboratory Research 17/1 77-82.
- Fairhall S, Albi A, Melcher D (2014) Temporal Integration Windows for Naturalistic Visual Sequences PLOS One 9/7 e102248.
- Farooqui T. (2007) Octopamine-Mediated Neuromodulation of Insect Senses Neurochem Res 32 1511-1529 doi:10.1007/s11064-007-9344-7
- Farrant K, Uddin L (2015) Asymmetric development of dorsal and ventral attention networks in the human brain Developmental Cognitive Neuroscience 12 165-174.
- Feltz A & Cokely E (2009) Do judgments about freedom and responsibility depend on who you are? Personality differences in intuitions about compatibilism and incompatibilism Consciousness and Cognition 18 342-350.
- Feltz A et al. (2009) Natural Compatibilism versus Natural Incompatibilism: Back to the Drawing Board Mind & Language 24 1.
- Felder C. et al. (1999) The venus flytrap of periplasmic binding proteins: an ancient protein module present in multiple drug receptors AAPS Pharm Sci. 1/2 E2.
- Fisher M (2015) Quantum Cognition: The possibility of processing with nuclear spins in the brain ArXiv: 1508.05929, Annals of Physics 362 593.
- Foster B & Foster M (1998) The Secret Lives of Alexandra David-Neel Overlook Press, NY.
- Fox D. (2008) The secret life of the brain New Scientist 5 Nov.
- Freeman W. (1991) The physiology of perception. Sci. Am. 264 Feb 35-41.
- French C. (2012) Precognition studies and the curse of the failed replications Guardian 15 Mar http://www.theguardian.com/science/2012/mar/15/precognition-studies-curse-failed-replications
- Fried I., Katz A., McCarthy G., Sass K., Williamson P., Spencer S. (1991) Functional Organization of Human Supplementary Motor Cortex Studied by Electrical Stimulation The Journal of Neuroscience, 1(11) 3656-3666.
- Fritz-Laylin L et al. (2010) The genome of Naegleria gruberi illuminates early eukaryotic versatility Cell 140, 631- 642.
- Gaillard R., Dehaene S., Adam C., Clemenceau S., Hasboun D. (2009) Converging intracranial markers of conscious access. PLoS Biol 7(3) e1000061. doi:10.1371/journal.pbio.1000061.
- Ghirardi G, Rimini A, Weber T (1986) Unified dynamics for microscopic and macroscopic systems, Phys. Rev. D 34 470-491.
- Giachello C et al. (2016) Magnetic Fields Modulate Blue-Light-Dependent Regulation of Neuronal Firing by Cryptochrome J. Neurosci. 36(42) 10742-49.
- Gidon et al. (2020) Dendritic action potentials and computation in human layer 2/3 cortical neurons Science 367 83-87 doi:10.1126/science.aax6239.
- Giroldini W et al. (2015) EEG correlates of social interaction at distance F1000 doi:10.12688/f1000research.6755.5.
- Goldbeter A (2006) Oscillations and waves of cyclic AMP in Dictyostelium: A prototype for spatio-temporal organization and pulsatile intercellular communication Bull Math Biol 68 1095-1109.
- Gonzales-Perdomo, M., Romero, P., & Goldenberg, S. (1988). Cyclic AMP and adenylate cyclase activators stimulate Trypanosoma cruzi differentiation. Experimental parasitology, 66(2), 205-212.
- Grau C et al. (2014) Conscious Brain-to-Brain Communication in Humans Using Non-Invasive Technologies PLoS ONE 9/8 e105225. doi:10.1371/journal.pone.0105225.
- Graziano M (2016) A New Theory Explains How Consciousness Evolved The Atlantic 6 Jun.
- Green M (2008) Reality -an emerging representation of the world http://fqxi.org/community/forum/topic/330.
- Green M (2014) Unified meta-theory of information, consciousness, time and the classical-quantum universe ArXiv:1309.4084.
- Gu, M., Chrzanowski, H., Assad, S., Symul, T., Modi, K., Ralph, T., Vedral, V. & Lam, P. (2012) Observing the operational significance of discord consumption Nature Physics DOI: 10.1038/NPHYS2376.
- Gunther et al. (2018) Double-Cone Localization and Seasonal Expression Pattern Suggest a Role in Magnetoreception for European Robin Cryptochrome 4 Curr. Biol. doi:10.1016/j.cub.2017.12.003
- Haggard P. (2005) Conscious intention and motor cognition TRENDS in Cognitive Sciences 9/6 290-295.
- Halloy, J., Lauzeral, J., & Goldbeter, A. (1998). Modeling oscillations and waves of cAMP in Dictyostelium discoideum cells. Biophysical chemistry, 72(1), 9-19.
- Harmelech, T., Preminger, S., Wertman, E., Malach, R. (2013). The Day-After Effect: Long Term, Hebbian-Like Restructuring of Resting-State fMRI Patterns Induced by a Single Epoch of Cortical Activation. The Journal of Neuroscience, 33(22), 9488-9497.
- Haroush K and Williams Z (2015) Neuronal Prediction of Opponent's Behavior during Cooperative Social Interchange in Primates Cell 160, 1-13.
- Harris S (2012) Free Will New York: Free Press. http://youtu.be/2L1a7CHYVLg.
- Hearn, M. G., Ren, Y., McBride, E. W., Reveillaud, I., Beinborn, M., & Kopin, A. S. (2002). A Drosophila dopamine 2-like receptor: Molecular characterization and identification of multiple alternatively spliced variants. Proceedings of the National Academy of Sciences, 99(22), 14554-9.
- Heaven D. (2013) Echoes in the brain open a window on yesterday New Scientist 27 Jun.
- Hermens R (2014) Conway-Kochen and the Finite Precision Loophole Found Phys 44 1038-1048 doi:10.1007/s10701-014-9827-8
- Hildner, R., Brinks, D., Nieder, J. B., Cogdell, R. J., & van Hulst, N. F. (2013). Quantum Coherent Energy Transfer over Varying Pathways in Single Light-Harvesting Complexes. Science, 340(6139), 1448-1451. doi: 10.1126/science.1235820
- Hinrichsen, R. D., Schultz, J. E. (1988) Paramecium: a model system for the study of excitable cells. Trends in neurosciences, 11(1), 27-32.
- Hiscock et al. (2016) The quantum needle of the avian magnetic compass PNAS doi:10.1073/pnas.1600341113
- Hosten O. (2011) How to catch a wave Nature 474 170-1.
- Hosten O., Kwiat P. (2008) Observation of the Spin Hall Effect of Light via Weak Measurements Science 319 787- 790.
- Hubbard J, Gazzaley A, Morsella E (2011) Traditional response interference effects from anticipated action outcomes: A response-effect compatibility paradigm Acta Psychologica 138 106-110.
- Hubbard et al. (2013) Representations in working memory yield interference effects found with externally-triggered representations Acta Psychologica 142 127-135.
- Iyer, L. M., Aravind, L., Coon, S. L., Klein, D. C., & Koonin, E. V. (2004). Evolution of cell-cell signaling in animals: did late horizontal gene transfer from bacteria have a role?. TRENDS in Genetics, 20(7), 292-299.
- Johansson P et al. (2005) Failure to Detect Mismatches Between Intention and Outcome in a Simple Decision Task Science 310 116-9.
- Jones D (2011) The Free Will Delusion New Scientist 210/2808 32-5.
- Jung, Carl G. (1993) [1952]. Synchronicity: An Acausal Connecting Principle. Bollingen, Switzerland: Bollingen Foundation. ISBN 978-0-691-01794-5.
- Jung-Beeman, Mark (2008) The Eureka Hunt New Yorker July 28 84/22 40.
- Kane R (1996) The Significance of Free Will Oxford University Press.
- King C. C. (1991) Fractal and Chaotic Dynamics in Nervous Systems 1991 Progress in Neurobiology 36 279-308.
- Kim Y, Yu R, Kulik S, Shih Y (2000) Delayed "Choice" Quantum Eraser Phys Rev Lett 84 See: en.wikipedia.org/wiki/Delayed_choice_quantum_eraser
- King C. C. (2002) Biocosmology http://www.dhushara.com/book/bchtm/biocos.htm
- King C. C. (2008) The Central Enigma of Consciousness Nature Precedings 5 November 2008 Journal of Consciousness Exploration and Research 2(1) 2011 http://www.dhushara.com/enigma/enigma.htm
- King C. C. (2011) The Tree of Life: Tangled Roots and Sexy Shoots, DNA Decipher Journal 1(1) 73-109.
- King C. C. (2012) Entheogens, the Conscious Brain and Existential Reality http://www.dhushara.com/psyconcs/psychconsc8.htm
- King C. C. (2013) Exploring Quantum, Classical and Semi-Classical Chaos in the Stadium Billiard Quanta 3/1 16- 31 DOI: 10.12743/quanta.v3i1.23
- Kirschfeld, K., (1992). Oscillations in the insect brain: do they correspond to the cortical gamma waves of vertebrates? Proc. Natl. Acad. Sci. USA 89, 4764-8.
- Kocsis, S., Braverman, B., Ravets, S., Stevens, M. J., Mirin, R. P., Shalm, L. K., & Steinberg, A. M. (2011). Observing the average trajectories of single photons in a two-slit interferometer. Science, 332(6034), 1170- 1173.
- Köhidai , L., Vakkuri, O., Keresztesi, M., Leppaluoto, J., & Csaba, G. (2003). Induction of melatonin synthesis in Tetrahymena pyriformis by hormonal imprinting-A unicellular" factory" of the indoleamine. Cellular And Molecular Biology-Paris-Wegmann-, 49(4), 521-524.
- Kosem A, Gramfort A, van Wassenhove V (2014) Encoding of event timing in the phase of neural oscillations NeuroImage doi:10.1016/j.neuroimage.2014.02.010.
- Koubeissi M, Bartolomei F, Beltagy A, Picard F (2014) Electrical stimulation of a small brain area reversibly disrupts consciousness Epilepsy & Behavior 37 32-35.
- Kramer, P. (1993) Listening to Prozac Penguin, New York.
- Kravitz E.A. (2000) Serotonin and aggression: insights gained from a lobster model system and speculations on the role of amine neurons in a complex behavior J. Comp. Physiol. 186 221-238.
- Krippner S, Honorton C, Ullman M (1973) An experiment in dream telepathy with "The Grateful Dead." J. Am. Soc. of Psychosomatic Dentistry and Medicine 20 9-17.
- Lampinen, M., Pentikäinen, O., Johnson, M. S., & Keinänen, K. (1998). AMPA receptors and bacterial periplasmic amino acid-binding proteins share the ionic mechanism of ligand recognition. The EMBO journal, 17(16), 4704- 4711.
- Lampinen M. et al. (1998) AMPA receptors and bacterial periplasmic amino acid-binding proteins share the ionic mechanism of ligand recognition EMBO 17/16 4704-4711.
- Landsman K, Cator E (2014) Constraints on Determinism: Bell Versus Conway-Kochen Found Phys 44 781-791 doi:10.1007/s10701-014-9815-z.
- Leung L et al. (2019) Neural signatures of sleep in zebrafish Nature doi:10.1038/s41586-019-1336-7.
- Levenson J., Sweatt D. (2005) Epigenetic Mechanisms In Memory Formation Nature Reviews Neuroscience 6 108. Libet, B., Gleason, C. A., Wright, E. W., & Pearl, D. K. (1983). Time of conscious intention to act in relation to onset of cerebral activity (readiness-potential) the unconscious initiation of a freely voluntary act. Brain, 106(3), 623-642
- Libet B. (1989) The timing of a subjective experience Behavioral Brain Sciences 12 183-5. (See also Libet, B. et al. (1985) Behav. Brain Sci. 8, 529-566.)
- Liebeskind, B. J., Hillis, D. M., & Zakon, H. H. (2011). Evolution of sodium channels predates the origin of nervous systems in animals. Proceedings of the National Academy of Sciences, 108(22), 9154-9159. doi/10.1073/pnas.1106363108
- Liljenström Hans, Svedin Uno (2005) Micro-Meso-Macro: Addressing Complex Systems Couplings Imperial College Press.
- Lin J, Marcolli M, Ooguri H, Stoica B (2015) Locality of Gravitational Systems from Entanglement of Conformal Field Theories Phys. Rev. Lett. 114, 221601.
- Locher, C. P., Ruben, P. C., Gut, J., & Rosenthal, P. J. (2003). 5HT1A serotonin receptor agonists inhibit Plasmodium falciparum by blocking a membrane channel. Antimicrobial agents and chemotherapy, 47(12), 3806-3809.
- London M, Roth A, Beeren L, Hausser M, Latham P (2010) Sensitivity to perturbations in vivo implies high noise and suggests rate coding in cortex Nature 466 123-8.
- Lundeen J. S., Steinberg A. M. (2009) Experimental Joint Weak Measurement on a Photon Pair as a Probe of Hardy's Paradox Physical review letters 102 020404.
- Lundeen J.S., Sutherland B., Patel A., Stewart C, Bamber C. (2011) Direct measurement of the quantum wavefunction Nature 474 188-191.
- Lush P, Naish P, Dienes Z (2016) Metacognition of intentions in mindfulness and hypnosis Neuroscience of Consciousness 1/10 doi:10.1093/nc/niw007.
- Ma X et al. (2012) Experimental delayed-choice entanglement swapping arxiv.org/pdf/1203.4834v2.pdf
- Macrae C., Heatherton T., Kelley W. (2004) A Self Less Ordinary: The Medial Prefrontal Cortex and You.in Cognitive Neurosciences III. Ed Michael S. Gazzaniga. MIT Press. http://dartmouth.edu/~thlab/pubs/04_Macrae_etal_CogNeuroIII.pdf
- Mason M et al. (2007) Wandering minds: The default network and stimulus-independent thought Science 315 393- 5.
- McAlpine K. (2010) Nature's hot green quantum computers revealed New Scientist 3 February http://www.newscientist.com/article/mg20527464.000-natures-hot-green-quantum-computers-revealed.html
- McCauley, D.W. (1997) Serotonin plays an early role in the metamorphosis of the hydrozoan Phialidium gregarium Dev. Biol. 190 229-240.
- McGowan , K., Guerina, V., Wicks, J., & Donowitz, M. (1985). Secretory hormones of Entamoeba histolytica. In Ciba Foundation Symposium 112-Microbial Toxins and Diarrhoeal Disease (pp. 139-154). John Wiley & Sons, Ltd. Megidish E, Halevy A, Shacham T, Dvir T, Dovrat L, Eisenberg H (2012) Entanglement Between Photons that have Never Coexisted arXiv1209.4191.
- Merali Z. (2010) Back From the Future Discover Magazine August 26.
- Mestler, T. (2011). Excitable Signal Relay and Emergent Behavior in the Social Amoeba Dictyostelium discoideum. Princeton University.
- Moore J et al. (2017) Dynamics of cortical dendritic membrane potential and spikes in freely behaving rats Science 10.1126/science.aaj1497.
- Moreva E, Brida G, Gramegna M, Giovannetti V, Maccone L, Genovese M (2014) Time from quantum entanglement: an experimental illustration ArXiv http://arxiv.org/pdf/1310.4691v1.
- Morsella E et al. (2016) Homing in on Consciousness in the Nervous System: An Action-Based Synthesis Behavioral and Brain Sciences (forthcoming) doi:10.1017/S0140525X15000643.
- Mozes E (2003) The Dogmatic Determinism of Daniel Dennett Navigator Dec http://www.atlassociety.org/daniel_dennett_freedom_evolves.
- Mozes E (2013) Review Essay: Sam Harris's Free Will Reason Papers 35/1 http://reasonpapers.com/pdf/351/rp_351_15.pdf.
- Murch, K. W., Weber, S. J., Macklin, C. & Siddiqi, I. (2013) Observing single quantum trajectories of a superconducting quantum bit Nature 502, 211-214.
- Molnár, G., Oláh, S., Komlósi, G., Füle, M., Szabadics, J., Varga, C., ... & Tamás, G. (2008). Complex events initiated by individual spikes in the human cerebral cortex. PLoS biology, 6(9), e222.
- Nahmias E et al. (2006) Is Incompatibilism Intuitive? Philosophy and Phenomenological Research 73 28. Nahmias E et al. (2007) Free Will, Moral Responsibility, and Mechanism: Experiments on Folk Intuitions Midwest Studies in Philosophy 31 214.
- Nichols S, Knobe J (2007) Moral Responsibility and Determinism: The Cognitive Science of Folk Intuitions Noûs, 41 663.
- Nithianantharajah, J., Komiyama, N. H., McKechanie, A., Johnstone, M., Blackwood, D. H., St Clair, D., ... & Grant, S. G. (2012). Synaptic scaffold evolution generated components of vertebrate cognitive complexity. Nature neuroscience. doi:10.1038/nn.3276.
- Nomura, T., Tazawa, M., Ohtsuki, M., Sumi-Ichinose, C., Hagino, Y., Ota, A., ... & Nagatsu, T. (1998). Enzymes related to catecholamine biosynthesis in< i> Tetrahymena pyriformis</i>. Presence of GTP cyclohydrolase I. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 120(4), 753-760.
- Oh, B. H., Kang, C. H., De Bondt, H., Kim, S. H., Nikaido, K., Joshi, A. K., & Ames, G. F. (1994). The bacterial periplasmic histidine-binding protein. structure/function analysis of the ligand-binding site and comparison with related proteins. Journal of Biological Chemistry, 269(6), 4135-4143.
- Olafsdottir H, Barry C, Saleem A, Hassabis D, Spiers H (2015) Hippocampal place cells construct reward related sequences through unexplored space eLife 2015/4:e06063 doi:10.7554/eLife.06063.
- Ollivier H. & Zurek W (2002) Quantum Discord: A Measure of the Quantumness of Correlations Phys. Rev. Lett. 88/1 017901.
- Pagel M. (2012) How to measure consciousness New Scientist 1 August http://www.newscientist.com/article/mg21528762.000-how-to-measure-consciousness.html
- Paul S et sl. (2017) Magnetic field effect in natural cryptochrome explored with modelcompound Scientific Reports 7 11892 doi:10.1038/s41598-017-10356-4.
- Paulk, A. C., Gronenberg, W. (2008). Higher order visual input to the mushroom bodies in the bee, Bombus impatiens. Arthropod structure & development, 37(6), 443-458.
- Peroutka S. (1995) Serotonin receptor subtypes: Their evolution and clinical significance CNS Drugs 4 supp1 18- 28.
- Peroutka, S., Howell, T. (1994) The molecular evolution of G-protein-coupled receptors: focus on 5- hydroxytryptamine receptors Neuropharmacology 33 319-324.
- Pikovski I, Zych M, Costa F, Brukner C (2015) Universal decoherence due to gravitational time dilation Nature Physics doi:10.1038/nphys3366.
- Pokorny F et al. (2019) Tracking the dynamics of an ideal quantum measurement arXiv:1903.10398.
- Poznanski R et al. (2017) Consciousness as a quantum dynamic effect in Biophysics of Consciousness A Foundational Approach Poznanski R, Tuszynski J, Feinberg T (eds) World Scientific.
- Pribram K (1991). Brain and perception: Holonomy and structure in figural processing. Psychology Press.
- Pribram K (1999) Quantum holography: Is it relevant to brain function? Information Sciences 115 (1-4) 97-102 doi:10.1016/S0020-0255(98)10082-8.
- Pribram K, Meade S (1999). Conscious awareness: Processing in the synaptodendritic web New Ideas in Psychology 17/3 205-214 doi:10.1016/S0732-118X(99)00024-0.
- Pribram K (2004) Consciousness Reassessed Mind and Matter 2 7-35.
- Pronin E, Kugler M (2010) People believe they have more free will than others PNAS 107 22469. Pryluk et al. (2019) A Tradeoff in the Neural Code across Regions and Species Cell 176 597-609 doi:10.1016/j.cell.2018.12.032.
- Qasim S, Fried I, Jacobs J (2021) Phase precession in the human hippocampus and entorhinal cortex Cell 184, 3242-3255 doi:10.1016/j.cell.2021.04.017.
- Quiroga R., Mukamel R., Isham E., Malach R., Fried I. (2008) Human single-neuron responses at the threshold of conscious recognition PNAS 105/9 3599-3604.
- Radin, Dean (2009) Entangled Minds; Extrasensory Experiences In Quantum Reality Pocket Books.
- Raichle M. et al. (2001) A default mode of brain function PNAS 98/2 676-682.
- Raichle M. & Snyder A. (2007) A default mode of brain function: A brief history of an evolving idea NeuroImage 37 1083-1090.
- Reuter, F., Del Cul, A., Malikova, I., Naccache, L., Confort-Gouny, S., Cohen, L., ... & Audoin, B. (2009). White matter damage impairs access to consciousness in multiple sclerosis. Neuroimage, 44(2), 590-599.
- Rahnama M et al. (2010) Emission of Mitochondrial Biophotons and their Effect on Electrical Activity of Membrane via Microtubules arXiv:1012.3371.
- Ritchie S, Wiseman R, French C (2012) Failing the Future: Three Unsuccessful Attempts to Replicate Bem's 'Retroactive Facilitation of Recall' Effect PLoS ONE 7/3 e33423. doi:10.1371/journal.pone.0033423.
- Rovelli C (2013) Free Will, Determinism, Quantum Theory And Statistical Fluctuations: A Physicist's Take Edge 7.8.13.
- Ryan T., Grant S. (2009) The origin and evolution of synapses Nature Reviews Neuroscience 10 701-12.
- Ryle, Gilbert (1949, 2000) The Concept of Mind New University of Chicago Press.
- Samuel E. (2001) Seeing the seeds of cancer New Scientist 24 Mar 42-45.
- Sarkissian H et al. (2010) Is Belief in Free Will a Cultural Universal? Mind & Language 25/3 346-358.
- Schlenkrich T, Ports M & Huader D (1995) A rapid, simple method for the isolation and characterization of the photoreceptor of Dictyostelium discoideum amoebae FEBS Letters 364 276-278.
- Schnakers C. (2009) Detecting consciousness in a total locked-in syndrome: An active event-related paradigm Neurocase 15/4 271-7.
- Schurger A, Pereira F, Treisman A,Cohen J (2010) Reproducibility Distinguishes Conscious from Nonconscious Neural Representations Science 327 97 doi:10.1126/science.1180029.
- Schurger A., Sitt J., Dehaene S. (2012) An accumulator model for spontaneous neural activity prior to self-initiated movement PNAS doi:10.1073.pnas.1210467109.
- Schurger A, Sarigiannidis I, Naccachee L, Sitt J, Dehaene S (2015) Cortical activity is more stable when sensory stimuli are consciously perceived PNAS doi:10.1073/pnas.1418730112.
- Schurger A, Uithol S (2015) Nowhere and Everywhere: The Causal Origin of Voluntary Action Rev. Phil. Psych. doi:10.1007/s13164-014-0223-2.
- Schütt, A., Basar, E., (1992). The effects of acetylcholine, dopamine and noradrenaline on the visceral ganglion of Helix Pomatia II: Stimulus evoked field potentials. Compar. Biochem. Physiol. 102C, 169-176.
- Schwaerzel, M., Monastirioti, M., Scholz, H., Friggi-Grelin, F., Birman, S., & Heisenberg, M. (2003). Dopamine and octopamine differentiate between aversive and appetitive olfactory memories in Drosophila. The Journal of neuroscience, 23(33), 10495-10502.
- Selcho, M., Pauls, D., Han, K. A., Stocker, R. F., & Thum, A. S. (2009). The role of dopamine in Drosophila larval classical olfactory conditioning. PLoS One, 4(6), e5897.
- Sergent C., Baillet S., Dehaene S. (2005) Timing of the brain events underlying access to consciousness during the attentional blink Nature Neuroscience 8/10 1391-1400.
- Sheldrake R (1981) A New Science of Life: The hypothesis of formative causation J.P. Tarcher LA CA ISBN 978- 1-84831-042-1.
- Sheldrake R (1988) The Presence of the Past: Morphic resonance and the habits of nature Times Books NY, ISBN 0-8129-1666-2.
- Siclari F et al. (2017) The neural correlates of dreaming Nature Neuroscience doi:10.1038/nn.4545
- Siegfried T (2014) Finding a quantum way to make free will possible Science News 26 Feb.
- Siegelmann H. (1995) Computation Beyond the Turing Limit Science 268 545-8.
- Sigman M., Dehaene S. (2005) Parsing a cognitive task: A characterization of the mind's bottleneck. PLoS Biol 3(2) e37.
- Sigman M., Dehaene S. (2006) Dynamics of the central bottleneck: Dual-task and task uncertainty. PLoS Biol 4(7) e220. DOI: 10.1371/journal.pbio.0040220
- Skarda C., Freeman W., (1987) How brains make chaos in order to make sense of the world Behavioral and Brain Sciences 10 161-195.
- Solovey et al. (2015) Loss of Consciousness Is Associated with Stabilization of Cortical Activity J. Neuroscience, DOI: 10.1523/jneurosci.4895-14.2015.
- Soon C., Brass M., Heinze H., Haynes J. (2008) Unconscious determinants of free decisions in the human brain. Nature Neuroscience 11(5): 543-545. doi:10.1038/nn.2112.
- Sosa, M. A., Spitzer, N., Edwards, D. H., & Baro, D. J. (2004). A crustacean serotonin receptor: cloning and distribution in the thoracic ganglia of crayfish and freshwater prawn. Journal of Comparative Neurology, 473(4), 526-537.
- Spinney L (2015) The time illusion: How your brain creates now New Scientist 7 Jan. Steck D. (2009) Passage through chaos Nature 461 736-7.
- Stillman T et al. (2010) Personal Philosophy and Personnel Achievement: Belief in Free Will Predicts Better Job Performance Social Psychological and Personality Science 1/1 43-50.
- Takeda N., Sugiyama K. (1993) Metabolism of biogenic monoamines in the ciliated protozoan, Tetrahymena pyriformis Comparative biochemistry and physiology 106/1 63-70.
- Taniura, H., Sanada, N., Kuramoto, N., & Yoneda, Y. (2006). A metabotropic glutamate receptor family gene in Dictyostelium discoideum. Journal of Biological Chemistry, 281(18), 12336-12343.
- Thakral P (2011) The neural substrates associated with inattentional blindness Consciousness and Cognition 20 1768-75.
- Thyrhaug E et al (2018) Identification and characterization of diverse coherences in the Fenna-Matthews-Olson complex, Nature Chemistry doi:10.1038/s41557-018-0060-5.
- Tinsley J. et al. (2016) Direct detection of a single photon by humans. Nature Communications doi:10.1038/ncomms12172.
- Trevena J., Miller J. (2010) Brain preparation before a voluntary action: Evidence against unconscious movement initiation Consciousness and Cognition, 19/1, 447-456 DOI: 10.1016/j.concog.2009.08.006.
- Tse P (2013) Free will unleashed / A biological basis for free will New Scientist 5 Jun.
- Tumulka R (2007) The Point Processes of the GRW Theory of Wave Function Collapse arXiv:0711.0035.
- Tumulka R (2007) Comment on "The Free Will Theorem" Foundations of Physics 37/2 doi: 10.1007/s10701-006- 9098-0.
- Turano, F. J., Panta, G. R., Allard, M. W., & van Berkum, P. (2001). The putative glutamate receptors from plants are related to two superfamilies of animal neurotransmitter receptors via distinct evolutionary mechanisms. Molecular biology and evolution, 18(7), 1417-1420.
- Umbach G et al. (2020) Time cells in the human hippocampus and entorhinal cortex support episodic memory PNAS 117/45 28463-28474 doi:10.1073/pnas.2013250117.
- Umbriaco, D., Anctil, M., & Descarries, L. (1990). Serotonin-immunoreactive neurons in the cnidarian Renilla koellikeri. Journal of Comparative Neurology, 291(2), 167-178.
- Vohs K & Schooler J (2008) The Value of Believing in Free Will Encouraging a Belief in Determinism Increases Cheating Psychological Science 9 49.
- Warren W. (1998) MR Imaging contrast enhancement based on intermolecular zero quantum coherences Science 281 247.
- Wegner D & Wheatley T (1999) Apparent mental causation: Sources of the experience of will American Psychologist 54/7 480-492.
- Westerhoff J (2013) The self: You think you live in the present? New Scientist 20 February.
- Weyrer , S., Rutzler, K., & Rieger, R. (1999). Serotonin in Porifera? Evidence from developing Tedania ignis, the Caribbean fire sponge (Demospongiae). Memoirs-Queensland Museum, 44, 659-666
- Williams C. (2012) Are these the brain cells that give us consciousness? New Scientist 20 Jul.
- Wilson C. (2013) Consciousness: Why aren't we all zombies? New Scientist 15 May.
- Wilson C. (2015) Rats dream about the places they wish to go New Scientist 26 Jun.
- Witteveen J (2013) Lack of serotonin reuptake during brain development alters rostral raphe-prefrontal network formation Front. Cell. Neurosci. doi:10.3389/fncel.2013.00143.
- Wittmann M (2011) Moments in Time Frontiers in Integrative Neuroscience 5 66 doi: 10.3389/fnint.2011.00066.
- Woodruff A ., Yuste R. 2008 Of Mice and Men, and Chandeliers PLOS Biology 6/9 243
- Young, S.N., Leyton, M. (2002) The role of serotonin in human mood and social interaction. Insight from altered tryptophan levels Pharmacol. Biochem. Behav. 71 857-865.
- Zimmer C. (2005) The Neurobiology of the Self Scientific American Nov 93. Zurek W (1982) Environment-induced superselection rules Phys. Rev. D 26, 1862.
- Zurek W. (1991) Decoherence and the Transition from Quantum to Classical Physics Today Oct Zurek W (2003) Decoherence and the transition from quantum to classical -Revisited arXiv:quant-ph/0306072. Zurek W (2009) Quantum Darwinism Nature Physics 5 181-188.