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Microglia

Profile image of Denis SouletDenis Soulet

2008, Current Biology

https://doi.org/10.1016/J.CUB.2008.04.047
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3 pages

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Abstract
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Microglia, the resident immune cells of the central nervous system (CNS), have diverse origins and functional roles in maintaining brain homeostasis and responding to injury and disease. They originate from primitive macrophages and can proliferate in response to various conditions. Microglial cells exhibit dynamic morphological changes based on their environment, indicating their adaptive nature. The study discusses the ontogeny of microglia, their subtypes, and their interactions within the CNS, particularly under pathological conditions, emphasizing the ongoing debates regarding their origins and functions.

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