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Medicine and Health Sciences
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Genome science performed with e-science tools

Profile image of Martin SengerMartin Senger

2004

Abstract

In this paper we describe the use of my Grid middleware services to create and manage the information from running in silico bioinformatics experiments in a semantically enriched Grid aware environment. Through the development and application of workflows using my Grid components in the context of mapping the complex genomic region associated with the sporadically occurring genetic disorder Williams-Beuren Syndrome, scientists have not only produced biologically interesting and valid results, but also dramatically improved their productivity by undertaking repetitive tasks significantly faster and with an increased diligence compared to previous manual undertakings. In this work we have demonstrated the utility of an e-Science approach to the management of in silico experiments.

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References (22)

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