What dose DOES a micro-crystal really absorb?

Langmuir, 2009

The crystallization of micelles formed by surfactant F127 solvated by 20% in water was investigated in the vicinity of a hydrophilic interface. Upon entering the crystalline phase from low temperature, a large correlation length develops without preferential texture. Upon heating, the correlation length decreases and Oswald ripening is observed with crystallites orienting with respect to each other while retaining long-range and textured correlation.

A plastic compound used in some dermal fillers for the correction of wrinkles that are filled with a substance and released as the shell disintegrates Controlled release delivery Biodegradable microspheres are used to control drug release rates thereby decreasing toxic side effects, and eliminating the inconvenience of repeated injections. Microparticulate carrier system can be administered through different routes such as i.v,ocular,i.m,oral,intra arterial.etc.Each routes has it's own biological significance, limitation & pharmaceutical feasibility.

Super-absorbent water crystals A re hydrogels really so "super?" While gardeners may not be familiar with the term "hydrogel, " nearly everyone who has worried about watering plants has heard about "watering crystals" or "water retention granules." Th e ability of these synthetic polymers to absorb water and selectively bind to other substances has led to their use as soil stabilizers, water purifi ers, juice clarifi ers, animal feed thickeners, and in the processing of oil, pulp and paper, and fruits and vegetables. Moreover, they are widely used in cosmetics and other personal products, and have medical application in tissue augmentation (see "Polyacrylamides up close and very personal"). Although our main interest is in the eff ectiveness of garden-variety hydrogels, it is important to realize how widely these compounds are used in other contexts and to understand their positive-and negative-impacts. Th ere are two broad classes of polyacrylamide (PAM) hydrogels: soluble (linear) and insoluble (cross-linked). Linear PAM dissolves in water and has been successfully used in reducing irrigation-induced erosion in agricultural fi elds (see "Hydrogel use for erosion control"). Cross-linked PAM does not dissolve, but forms a gel when water is added and is oft en used in garden, landscape, and nursery situations as a way of retaining moisture. Insoluble PAM products are marketed as "superabsorbent gels" or "hydrating crystals." Instead of dissolving, these gels absorb water, swelling to many times their original size. As they dry, water is slowly released to the soil. Popular with the nursery industry and homeowners alike, these latter compounds are the focus of this article.

A plastic compound used in some dermal fillers for the correction of wrinkles that are filled with a substance and released as the shell disintegrates Controlled release delivery Biodegradable microspheres are used to control drug release rates thereby decreasing toxic side effects, and eliminating the inconvenience of repeated injections. Microparticulate carrier system can be administered through different routes such as i.v,ocular,i.m,oral,intra arterial.etc.Each routes has it's own biological significance, limitation & pharmaceutical feasibility.

Biosensors and …, 2005

Communications biology, 2024

2020

Magnetic microspheres hold great promise for reaching the goal of controlled and site specific drug delivery. Magnetic microspheres as an alternative to traditional radiation methods which uses highly penetrating radiations that is absorbed throughout the body. Its use is limited by toxicity and side effects. Now days, several targeted treatment systems including magnetic field, electric field, ultrasound, temperature, UV light and mechanical force are being used in many disease treatments (e.g. cancer, nerve damage, heart and artery, anti-diabetic, eye and other medical treatments). Among them, the magnetic targeted drug delivery system is one of the most attractive and promising strategy for delivering the drug to the specified site. Magnetically controlled drug targeting is one of the various possible ways of drug targeting. This technology is based on binding establish anticancer drug with ferrofluid that concentrate the drug in the area of interest (tumor site) by means of magn...

The adsorption of plasma proteins fibrinogen and fibronectin on Ti, TiO 2 and steel surfaces was examined using quartz-crystal microgravimetry with dissipation monitoring (QCM-D). Subsequent coupling of epitope-specific antibodies revealed information about the orientation of the protein molecules adhered to the surface, the results being confirmed by enzyme-linked immunosorbent assay (ELISA) measurements. QCM-D was also utilized for the characterization of osteoblast and fibroblast adsorption on the same materials. The evaluation of dissipation shifts plotted vs. changes of the resonance frequency showed significant differences in the timedependent behavior of the two cell lines adsorbed to the three material surfaces, thus proving QCM-D as a promising method for judging the specific cell reaction to a given surface and therefore predicting the in-vivo performance of medical implants. This method is valid especially in combination with a well known biocompatible surface as a control.

This article appeared in a journal published by Elsevier. The attached copy is furnished to the author for internal non-commercial research and education use, including for instruction at the authors institution and sharing with colleagues.

Microspheres are characteristically free flowing powders having particle size ranging from 1-1000 μm consisting of proteins or synthetic polymers. The range of Techniques for the preparation of microspheres offers a Variety of opportunities to control aspects of drug administration and enhance the therapeutic efficacy of a given drug. There are various approaches in delivering a therapeutic substance to the target site in a sustained controlled release fashion. It is the reliable means to deliver the drug to the target site with specificity, if modified, and to maintain the desired concentration at the site of interest. Moreover the microspheres are of micron size so they can easily fit into various capillary beds which are also having micron size. Microspheres received much attention not only for prolonged release, but also for targeting of anticancer drugs. There are various departments of medicine like cancer, pulmonary, cardiology, radiology, gynecology, and oncology etc., numerous drugs are used and they are delivered by various types of drug delivery system. Among them microspheric drug delivery system has gained enormous attention. The purpose of the review is to compile various types of microspheres, different methods to preparation, its applications and also various parameters to evaluate their efficiency.