JAVEDH SHAREEF

RAKMHSU, Clinical Pharmacy & Pharmacology, Faculty Member

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Phone: 00971565915310
Address: RAS AL KHAIMAH COLLEGE OF PHARMACEUTICAL SCIENCES
RAS AL KHAIMAH MEDICAL & HEALTH SCIENCE UNIVERITY
RAS AL KHAIMAH, UNITED ARAB EMIRATES

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Objectives: The study was carried out to assess the knowledge of the health professionals regardi... more Objectives: The study was carried out to assess the knowledge of the health professionals regarding biomedical waste management and to find out the effectiveness of the intervention phase in improving the knowledge of the health professionals. Method: The study sample included 100 health professionals. The pre-test and post-test scores of the health professionals were assessed using a validated selfadministered questionnaire. Results: The mean (31.97±4.751),mean percentage (79.925%), median (33.00), minimum (22.00) and maximum scores (38.00) obtained by the health professionals in the post-test phase was found to be significantly higher than the pre-test mean (18.49±5.130), mean percentage(46.225%), median(18.00),minimum(7.000)and maximum scores ( 29.00) respectively (p value<0.0001).The analysis of the pre-test and posttest scores using Wilcox on matched paired test proved that the

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A Study on Safe Use of Drugs in Elderly Patients in an Indian Teaching Hospital by Using BEERS and STOPP Criteria

Potentially inappropriate prescribing in elderly patients is a major health issue because it can ... more Potentially inappropriate prescribing in elderly patients is a major health issue because it can lead to negative outcomes and increases healthcare costs. The current study was designed to assess the potentially inappropriate medications (PIMs) prescribed in elderly patients in an Indian teaching hospital. A prospective cross sectional study was conducted on prescriptions of patients aged 65 and above visiting the outpatient general medicine department between August 2016 and March 2017. These prescriptions were reviewed for potentially inappropriate medication use by using beers criteria and STOPP criteria. A total of 200 prescriptions consisting of 131 (65.5%) males and 69 (34.5%) females were reviewed during the study. The mean age of the patients was found to be 72 years ± 4.986 S.D and the mean medication prescribed per patient was 3.83 ± 1.660 S.D. The beer’s criteria identified potentially inappropriate medication use in 17% of the patients whereas 8.5% of patients used at le...

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Assessment of Drug-Drug Interactions in Chronic Kidney Disease Patients in Nephrology Unit of a Tertiary Care Teaching Hospital

Review Article Evolving role of clinical pharmacist in the management of diabetes mellitus

Diabetes mellitus is a metabolic disorder characterised by hyperglycaemia due to impaired insulin... more Diabetes mellitus is a metabolic disorder characterised by hyperglycaemia due to impaired insulin secretion with or without insulin resistance. Uncontrolled blood glucose in the long term will lead to micro vascular and macro vascular complications with increased morbidity and mortality and negatively affecting the quality of life. Comprehensive diabetes care is a complex task that takes the entire team of healthcare professionals including the pharmacist to work together to provide, multidisciplinary care for patients. Pharmacist’s role has changed dramatically over the past three decades which has changed the concept of pharmacy from product oriented to a patient focused one with the concept of pharmaceutical care. The evolving role of clinical pharmacist in the management of diabetes mellitus - drug therapy, diabetes care and education has been described here. Optimizing the drug therapy for achieving the better therapeutic outcomes without causing drug related problems has been ...

Experiential training during COVID-19 pandemic: a virtual attachment experience from a college of pharmaceutical sciences in the United Arab Emirates

Pharmacy Education, 2021

Description: The COVID-19 pandemic compelled the traditional higher educational institutions to m... more Description: The COVID-19 pandemic compelled the traditional higher educational institutions to make a quick transition to the virtual instruction model. Considering the COVID-19 restrictions, the Department of Clinical Pharmacy and Pharmacology at Ras Al Khaimah College of Pharmaceutical Sciences, United Arab Emirates restructured their original onsite experiential training for final year Bachelor of Pharmacy students as a virtual online experience to ensure educational continuity. Evaluation: The virtual experiential training was conducted over two weeks and was imparted employing different virtual platforms like Google Classroom, Google Meet, Google Forms, Google Docs, etc. As a part of the community pharmacy training, the students were given different e-activities and tasks like e-case scenario analysis and interpretation, e-prescription screening, virtual patient education and were shown various 3-D animated videos related to community pharmacy. For the hospital training, the...

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Assessment of Drug Related Problems in Patients with Cardiovascular Diseases in a Tertiary Care Teaching Hospital

Backgrounds : Drug related problems can be defined as any event (or) circumstance involving the d... more Backgrounds : Drug related problems can be defined as any event (or) circumstance involving the drug treatment, which interferes or potentially interferes with the patient in achieving an optimum outcome of medical care. The aim of the study was to identify drug therapy problems and to assess the pharmacist interventions in patients with cardiovascular diseases. Methods: The inpatient case records including drug history and other relevant details of the admitted patients under the cardiology department were collected and reviewed by the clinical pharmacist for drug related problems. In case if any drug related problem was identified, was discussed with the concerned physician and suitable interventions was provided and documented. Results: A total of 112 patient case sheets were reviewed during the study period, out of which 53 drug related problems were identified from 44 patients. The most common drug related problem was found to be drug Interactions (49.05%) followed by Adverse D...

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Study on Knowledge and Attitude Related to Inherited Genetic Disorders

<jats:p>Increased prevalence of inherited genetic disorders is a significant public health ... more <jats:p>Increased prevalence of inherited genetic disorders is a significant public health problem that significantly affects the quality of life of the affected patients and their families in Arab countries. Knowledge about the disorders may empower the community by raising awareness about prevention methods and early detection to reduce the incidence of genetic disorders. This study was aimed to assess the knowledge and attitude related to inherited genetic disorders among health science university students in Ras Al Khaimah. A cross-sectional study was carried out for six months among health science university students in Ras Al Khaimah by using a validated self-administered questionnaire. A total of 359 students completed the study. The overall mean knowledge and attitude scores of the study respondents were 4.47 ± 1.81 and 5.37 ± 2.32, respectively. One hundred and six (29.5%) respondents had adequate knowledge, and a majority (74.65%) of the respondents showed a positive attitude towards genetic disorders. Lectures (25.5%) followed by the internet (20.7%) and healthcare professionals (15.7%) were the most cited sources of information. Comprehensive knowledge about genetic disorders was found to be low despite positive attitude and awareness among respondents. Strengthening knowledge about genetic education and mandatory premarital screening programs may help in early detection and prevention and thereby reducing the incidence of genetic disorders.</jats:p>

Impact of Pharmacist Provided Patient Counseling on Quality of Life Inpatients with Asthma in a Tertiary Care Teaching Hospital

Asthma is a chronic inflammatory condition of the airways, affecting millions of people worldwide... more Asthma is a chronic inflammatory condition of the airways, affecting millions of people worldwide. The common features of asthma are recurrent episodes of wheezing, breathlessness and chest tightness, associated with widespread narrowing of the airways. Increasing the knowledge of asthma, proper use of drugs and education of patients are the corner stone of the management of asthma. Patient education and counseling will lead to an increased patient confidence in the ability to self-manage of asthma, reduce hospitalization, increase adherence and improve quality of life. The study was carried out to assess the impact of patient counseling on the improvement in quality of life of asthmatic patients. A prospective interventional randomized study carried out for a period of 7 months from August 2012 to March 2013. The patients with asthma who met the study criteria were randomized into test (received counseling along with information leaflet)and control (received the counseling only at ...

Analysis of price variation among parenteral antibiotics available in a tertiary care teaching hospital

Journal of Patient Safety and Infection Control, 2017

Aims: Analysis of price variation among parenteral antibiotics available in a tertiary care teach... more Aims: Analysis of price variation among parenteral antibiotics available in a tertiary care teaching hospital. Settings and Design: Hospital pharmacy department. Subjects and Methods: Price, strength and brands of parenteral antibiotics included in the study were obtained from a computer database of hospital pharmacy department. The difference between the maximum and minimum prices of various brands manufactured by different companies with the same drug was analysed, and percentage variation and the cost ratio in the prices was estimated. Statistical Analysis Used: Descriptive statistics such as frequency and percentage. Results: Overall, prices of 15 single drug antibiotics available in 24 strengths marketed in 68 brands and 7 fixed-dose combinations available in 15 strength marketed in 49 brands were analysed. The maximum price variation and highest cost ratio between brands of single drug parenteral antibiotics were found to be more in amoxicillin 250 mg (270.43%) with cost ratio...

Effect of Pharmacist Led Educational Interventions on Disease Knowledge and Glycaemic Control in Patients with Diabetes Mellitus in a University Hospital

Current Research in Diabetes & Obesity Journal, Oct 14, 2016

Background: Diabetes mellitus is a chronic metabolic disorder that presents high morbidity and mo... more Background: Diabetes mellitus is a chronic metabolic disorder that presents high morbidity and mortality with significant reduction in patient's quality of life. The present study was conducted to evaluate the effect of pharmacist led educational interventions on disease knowledge and glycaemic control in patients with diabetes mellitus. Methodology: A prospective randomized educational interventional study was carried out in the General Medicine Outpatient department in a South Indian teaching hospital, Mangalore, Dakshina Kannada district for a period of 12 months from October 2014-September 2015. Results: A total of 106 patients who met the study criteria were enrolled and randomly divided into usual care and intervention groups. Data were collected by using a validated questionnaire developed by the researcher for overall diabetes knowledge to both the groups at the beginning and at the end of the study. The results showed a significant increase in overall diabetes knowledge from 18.05 to 25.43 (p <0.001) in the intervention group as compared to usual care group (19.78-18.07, p =0.007). The mean scores of patient's knowledge about diabetes, self-care practices and knowledge regarding complications of diabetes mellitus with respect to all the domains in the intervention group showed a significant improvement (p<0.05).A significant decrease (p<0.001) in the fasting and post prandial blood glucose levels was observed in the final follow up from the baseline period in the intervention group. Conclusion: The study highlights the positive impact of clinical pharmacist led intervention through education programme on improving disease knowledge and clinical outcomes in patient with diabetes mellitus.

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A Study on Assessment of Adverse Drug Reactions in Patients with Tuberculosis in a Tertiary Care Teaching Hospital

Journal of Applied Pharmaceutical Science, 2018

Tuberculosis is a chronic infectious disease caused by mycobacterium tuberculosis leading to incr... more Tuberculosis is a chronic infectious disease caused by mycobacterium tuberculosis leading to increased morbidity and mortality. Adverse drug reactions associated with Anti-tubercular drugs can result in non-compliance and therapeutic failure. The present study was aimed to identify the adverse drug reactions caused by anti-tubercular drugs and their assessment by using causality, severity and preventability scales. All the patients with tuberculosis admitted during the study period who met the study criteria were included and monitored for adverse drug reactions and were then subjected to assessment of causality, severity and preventability. A total of 95 patients were followed during the study period, out of which 22 patients developed 33 adverse drug reactions. Higher incidence of adverse drug reactions was observed in females (54.5%) than males (45.4%). The most common system associated with adverse drug reactions was found to be gastrointestinal system (45.5%). On evaluation of the causality assessment of adverse drugs reactions, majority of them were found to be 'probable' by both WHO and Naranjo scales. The severity assessment of adverse drug reactions by using Hart wig et al. showed that 60.7% of the adverse drug reactions were 'moderate' and 36.4% were 'mild'. Preventability assessment showed that majority of the adverse drug reactions was 'probably preventable'. The present study shows that implementing a system for regular adverse drug reactions monitoring may help to minimize morbidity and improve patient compliance and achieve better therapeutic outcome.

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A Study on Adverse Drug Reactions in Hospitalized Patients with Diabetes Mellitus in a Multi -Speciality Teaching Hospital

Asian Journal of Pharmaceutical and Clinical Research, 2016

Objectives: Adverse drug reactions (ADRs) are well known to occur with any class of drugs when us... more Objectives: Adverse drug reactions (ADRs) are well known to occur with any class of drugs when used in normal doses for the management of diseases. Anti-diabetic agents are no exception to this. The main aim of the study was to detect and analyze ADRs in hospitalized patients with diabetes mellitus in a multi-specialty hospital. Methods: The prospective observational study was conducted in a 1000 bed multi-disciplinary teaching hospital at Dakshin Kannada district in south India over a period of 2-year between June 2013 and May 2015. Results: A total of 102 ADRs were reported from 99 patients during the study period with male predominance (60.60%) over females. The average age of the patients in the study was found to be 59.8±13.15 years. The majority of the ADRs occurred in the age group of 40-80 years. The average duration of diabetes mellitus in the study was 10.08±7.69 years. The class of drugs most commonly responsible for causing ADRs was found to be anti-diabetic drugs (67.64...

Potential Psychotropic and COVID-19 Drug Interactions: A Comparison of Integrated Evidence From Six Database Programs

Cureus

Inborn errors of metabolism in the United Arab Emirates: Are our future healthcare providers knowing enough about it—A crosssectional study

Journal of Applied Pharmaceutical Science

Health literacy and positive attitude may influence the community in reducing the morbidity and m... more Health literacy and positive attitude may influence the community in reducing the morbidity and mortality associated with the inborn errors of metabolism (IEM). This study aimed to assess the knowledge and attitude related to IEM among health science university students in the United Arab Emirates. A cross-sectional survey-based study was carried out over 6 months using a self-administered questionnaire. Four hundred and fourteen students completed the study. The overall mean scores were compared using the t-test. There was a statistically significant (p < 0.0001) difference between knowledge and attitude scores among the study respondents. Most of the study participants had inadequate knowledge and had a positive attitude towards the IEM, which was statistically significant (p < 0.0001). The study also identified paucity among the study participants in recognizing the symptoms and most common IEM. Lectures (30.74%) followed by the Internet (19.25%) and healthcare professionals (18.72%) were the most cited sources of information. The study showed a low level of knowledge about IEM despite a positive attitude among respondents, emphasizing the need for such health-related subjects in the curriculum. This will enable the people to make informed decisions and instill into society the right attitude towards the consequent prevention and control of IEM.

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Trends and practices in prescribing anti-psychotropic medications in hospitalized patients with psychiatric disorders in a secondary care hospital in Ras al Khaimah

International Journal of Basic & Clinical Pharmacology

Background: Advances in the psycho-pharmacotherapy enhance the development of newer and better dr... more Background: Advances in the psycho-pharmacotherapy enhance the development of newer and better drugs in the management of psychiatric disorders. However, their proper utilization, safety and efficacy and adverse effects in the clinical practice needs continuous study. The study aimed to assess the trends and practice of prescribing psychotropic medications in hospitalized patients in a secondary care hospital in Ras Al Khaimah.Methods: A prospective observational study was carried out for a period of six months in a psychiatry department. All the patient details including the demographic data and prescribing pattern of antipsychotic medication were collected from the patient case records and were later analysed by using descriptive statistics.Results: A total of 50 patient’s prescription were analysed during the study period. Male (54%) predominance was noted over females (46%) with majority (64%) of patients were in the age group of 21-40 years. Schizophrenia (35.8%) was the most c...

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Development, Quality and Readability Assessment of Patient Information Leaflet for Diabetes Mellitus

Diabetes & Obesity International Journal

A Study on Potential Drug - Drug Interactions in Medicine Department of a Multi Specialty Teaching Hospital

Journal of Drug Delivery and Therapeutics

Aim of study: Drug-drug interaction (DDI) occurs when two or more drugs are simultaneously admini... more Aim of study: Drug-drug interaction (DDI) occurs when two or more drugs are simultaneously administered, where the effect of one drug is altered by the concomitant use of another drug. The prospective observational study aimed to assess the potential drug-drug interactions (pDDIs) in general medicine department of a multispecialty teaching hospital. Material & Methods: Data of all the patients admitted in the general medicine department was collected and analyzed for drug-drug interactions by using drug information resources such as "Thomson Reuters MICROMEDEX® 2.0 DRUGDEX and drugs.com. Results: A total of 150 case records were reviewed, 116 (77.33%) cases were identified with 273 potential drug-drug interactions during the study period. It was observed that out of the 273 DDIs identified, majority 68.13% of the interactions were moderate in severity followed by 19.78% were minor and 12.08% were major. The categorization of onset of drug-drug interactions revealed that 53.47% were categorized as 'not specified' and the documentation status of drugdrug interactions showed that 56.77% were 'fair' in nature. Conclusion: The study highlights the need of regular monitoring of drug therapy in identifying and preventing the medications that have the potential to cause drug-drug interactions thereby minimizing the undesirable outcomes in drug therapy and improving the quality of care.

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A Single Case Report on Hyponatremia Seizure Induced by Acetylcholinesterase Inhibitors

International Journal of Pharmacy and Pharmaceutical Sciences

Donepezil and memantine are the acetylcholinesterase inhibitors most commonly used in clinical pr... more Donepezil and memantine are the acetylcholinesterase inhibitors most commonly used in clinical practice for the management of mild-moderate dementia in Alzheimer’s disease. Electrolyte abnormalities associated with the drugs are commonly encountered in daily clinical practice and often can lead to seizures. Hyponatremia is an uncommon adverse effects of acetylcholinesterase inhibitors. Here we present a case on hyponatremia seizure due to the syndrome of inappropriate antidiuretic hormone (SIADH) caused by the acetylcholinesterase inhibitor donepezil and memantine as other likely causes were ruled out by appropriate investigations. The causality assessment needed to be done according to Naranjo algorithm was found to be ‘probable’ and the level of severity according to the Hartwig scale was ‘Level 5’.

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Study of Drug Utilization Pattern of Calcium, Vitamin D Supplements, and Anti-Osteoporosis Drugs in Patients with Osteoporotic Fracture: A Prospective Cross-Sectional Study

Asian Journal of Pharmaceutical and Clinical Research

Objective: This study was carried out to assess the drug utilization pattern of calcium, Vitamin ... more Objective: This study was carried out to assess the drug utilization pattern of calcium, Vitamin D supplements, and anti-osteoporosis drugs in patients with osteoporotic fracture in an Indian teaching hospital.Methods: A cross-sectional study was carried out for 6 months in outpatients receiving treatment from the orthopedic department of an Indian teaching hospital. Demographic details, comorbidities, types of fracture, laboratory parameters, and drug therapy were collected from the patient case records who met the study criteria and documented in the data collection form. All the collected details were later analyzed using descriptive statistics.Results: A total of 73 patient’s prescriptions were reviewed, in which 45.2% were male and 54.8% were female. Majority of the patients were in the age group of 50–60 years with mean age of 63.52±11.06 years. Hypertension (27.16%) was the highest comorbidity identified in the study followed by diabetes (18.51%) and coronary artery disease (...

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Study on bacteriological profile and antibiotic susceptibility pattern in patients with diabetic foot ulcers in a tertiary care teaching hospital

Journal of Social Health and Diabetes

Introduction:Diabetic foot ulcer and infections are one of the major complications in diabetic pa... more Introduction:Diabetic foot ulcer and infections are one of the major complications in diabetic patients leading to frequent hospitalization and increased mortality. Knowledge about the microbes that cause infections will be helpful for providing appropriate antimicrobial therapy. Aim:To evaluate the bacteriological profile of patients with diabetic foot ulcers and their antibiotic susceptibility pattern. Methodology:A cross-sectional study was carried out for a period of eight months in the Department of surgery in patients with diabetic foot ulcer at a tertiary care teaching hospital. Patient data relevant to the study were collected using a standard data collection form designed as per the need of the study. Details of the organisms isolated and susceptibility pattern were collected from microbiology department. Results:A total of 122 pathogens were identified from 71 patients with male (63.38%) predominance over females (36.61%). Out of the 71 patients, 38 (53.52%) patients had m...

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