Much work is required to understand how the conceptualizations that comprise business processes a... more Much work is required to understand how the conceptualizations that comprise business processes across the extended enterprise can be captured, represented, shared, and processed by both human and intelligent software agents. This effort will ultimately lead to transparent and secure information and knowledge flows in service and supply chains to increase economic efficiency in the digital economy.
2009 IEEE International Conference on Bioinformatics and Biomedicine Workshop, 2009
We present an algorithmic approach for determining, in polynomial time, disulfide bonds in protei... more We present an algorithmic approach for determining, in polynomial time, disulfide bonds in proteins using mass spectrometry data. The proposed technique is based on matching the set of all theoretically possible disulfide bonded structures with precursor ions derived from a tandem MS/MS experiment. For each match found, theoretical fragments from a disulfide bonded peptide structure are matched with precursor ion fragments obtained from the same tandem MS/MS data set in order to determine a protein's disulfide linkage pattern. A polynomial-time approximation strategy is proposed to selectively generate the set of theoretically possible disulfide bonded linkages for matching. Experiments demonstrate the efficacy of the method.
This chapter presents an Intelligent Knowledge-Based Multi-Agent Architecture for Collaboration (... more This chapter presents an Intelligent Knowledge-Based Multi-Agent Architecture for Collaboration (IKMAC) in B2B e-Marketplaces. IKMAC is built upon existing bodies of knowledge in intelligent agents, knowledge management, e-business, XML, and web service standards. This chapter focuses on the translation of data, information, and knowledge into XML documents by software 699 IKMAC seamless and transparent exchange of dynamic supply and demand information.
This article proposes an architecture to support information and knowledge exchange between colla... more This article proposes an architecture to support information and knowledge exchange between collaborating business partners. The focus is on knowledge representation and exchange by intelligent agents to support collaborative business functions through agents that exchange problem-specific information in standardized formats. The article then shows the application of the proposed architecture in the context of an infomediarybased B2B E-marketplace. Article: Emergent internet technologies already have had significant impacts on the business processes of today's organizations. New ways of conducting business with other businesses (B2B), directly with end consumers (B2C), and via new E-marketplaces have been implemented to facilitate transaction processing and coordinate processes among business partners. Increasingly, the Internet is seen by business organizations as a vehicle to create value. With an increasing number of parties involved in managing such a complex supply chain, the timely sharing of accurate information among collaborating partners becomes crucial to the efficiency of workflows and business operations (Rabin. 2003). However, a lack of systems and process integration, and the resultant lack of end-to-end value chain visibility, continue to hinder collaborative and mutually beneficial partnerships (Rabin, 2003). Information exchange, facilitated through technologies such as the Internet with its global connectivity, enables the creation of information partnerships among participants engaged in collaborative work across the entire supply chain. Information partnerships require system models that enable and support information integration, knowledge exchange, and thus improved collaboration among business partners. Such systems must provide trusted collaborating partners with "intelligent" capabilities for the seamless and transparent exchange of dynamic market information, including supply and demand conditions both synchronously and asynchronously, to attain their full business potential. Weber and Aha (2003) identified requirements for organizational knowledge management systems (KMS) where the central unit is a repository of knowledge artifacts (Holsapple and Joshi, 2001) collected from internal or external organizational sources. Here, knowledge repositories play a central role in the storage, distribution, and management of knowledge in an organization (Bolloju et al., 2002). Implementing and managing such knowledge integration capabilities over distributed and heterogeneous information platforms, such as the Internet, is a challenging task; yet, realizing this task can have huge benefits for organizations that embrace collaborative business paradigms. Recently, intelligent agents have gained significant interest as powerful modeling abstractions for B2B applications (Papazoglou, 2001). The assumption here is that the usage of software agents for processing information and knowledge flows can help increase the efficacy of an E-marketplace for its participants. Software agents work together by sharing process knowledge to achieve operational synergies for the goaloriented activities of individual entities in the system. Together-with emerging technologies like extensible Markup Language (XML) and Web Services, they provide opportunities to develop integrative E-marketplaces with suppliers or customers. INTELLIGENT AGENTS AND THEIR APPLICATION An intelligent agent is "a computer system situated in some environment and that is capable of flexible autonomous action in this environment in order to meet its design objectives" (Jennings and Wooldridge, 1998). The terms agents, software agents and intelligent agents are often used interchangeably in the literature.
Background: Advances in technology have led to the generation of massive amounts of complex and m... more Background: Advances in technology have led to the generation of massive amounts of complex and multifarious biological data in areas ranging from genomics to structural biology. The volume and complexity of such data leads to significant challenges in terms of its analysis, especially when one seeks to generate hypotheses or explore the underlying biological processes. At the state-of-the-art, the application of automated algorithms followed by perusal and analysis of the results by an expert continues to be the predominant paradigm for analyzing biological data. This paradigm works well in many problem domains. However, it also is limiting, since domain experts are forced to apply their instincts and expertise such as contextual reasoning, hypothesis formulation, and exploratory analysis after the algorithm has produced its results. In many areas where the organization and interaction of the biological processes is poorly understood and exploratory analysis is crucial, what is needed is to integrate domain expertise during the data analysis process and use it to drive the analysis itself. Results: In context of the aforementioned background, the results presented in this paper describe advancements along two methodological directions. First, given the context of biological data, we utilize and extend a design approach called experiential computing from multimedia information system design. This paradigm combines information visualization and human-computer interaction with algorithms for exploratory analysis of large-scale and complex data. In the proposed approach, emphasis is laid on: (1) allowing users to directly visualize, interact, experience, and explore the data through interoperable visualization-based and algorithmic components, (2) supporting unified query and presentation spaces to facilitate experimentation and exploration, (3) providing external contextual information by assimilating relevant supplementary data, and (4) encouraging user-directed information visualization, data exploration, and hypotheses formulation. Second, to illustrate the proposed design paradigm and measure its efficacy, we describe two prototype web applications. The first, called XMAS (Experiential Microarray Analysis System) is designed for analysis of time-series transcriptional data. The second system, called PSPACE (Protein Space Explorer) is designed for holistic analysis of structural and structure-function relationships using interactive low-dimensional maps of the protein structure space. Both these systems promote and facilitate human-computer synergy, where cognitive elements such as domain knowledge, contextual reasoning, and purpose-driven exploration, are integrated with a host of powerful algorithmic operations that support large-scale data analysis, multifaceted data visualization, and multi-source information integration. Conclusions: The proposed design philosophy, combines visualization, algorithmic components and cognitive expertise into a seamless processing-analysis-exploration framework that facilitates sense-making, exploration, and discovery. Using XMAS, we present case studies that analyze transcriptional data from two highly complex domains: gene expression in the placenta during human pregnancy and reaction of marine organisms to
Infomediaries play a critical role in e-marketplaces by managing the information flows to support... more Infomediaries play a critical role in e-marketplaces by managing the information flows to support business processes required of the e-marketplace [3]. Infomediaries bring together buyers and suppliers by identifying buyers with needs for suppliers' products and services and facilitating transactions between them. In addition, infomediaries provide value-added services in managing the information processes of the e-marketplace by deciphering complex product information and providing independent and observed assessment of the ...
eBusiness achieves business goals using information and knowledge exchange to enable execution of... more eBusiness achieves business goals using information and knowledge exchange to enable execution of inter-organizational business activities and support decision making underlying these activities. Mechanisms for knowledge transparency through standardized knowledge representation, storage, use, and sharing are essential to realize these goals. This paper addresses of knowledge integration and management for inter-organizational eBusiness processes. Building on research in Semantic eBusiness, eBusiness Processes, and knowledge management, we present a semantic knowledge integration framework for eBusiness Processes. Primary contributions of this paper include ontological engineering and knowledge representation for distributed knowledge management in inter-organizational eBusiness processes, knowledge representation for semantic knowledge management, and transparent knowledge sharing for semantic eBusiness processes. A description logics model for knowledge representation of an eMarketplace eBusiness process is presented as an illustrative example.
Business processes enable organizations to achieve business goals. Organizations require that the... more Business processes enable organizations to achieve business goals. Organizations require that their business processes exchange information in a secure environment. Access control mechanisms must be incorporated into the analysis, modeling, and design of business processes to prevent unauthorized access to information resources, to provide non-repudiation mechanisms, and to allow for segregation of duties. Existing methods in the design of secure information systems lack a conceptualization of secure business process. We develop the modeling concepts and modeling grammar that are used by the Secure Activity Resource Coordination (SARC) artifact to represent a secure business process. SARC can be used by business analysts to analyze and model secure business process. Using a real-world business process, we show how SARC can be used to create models that depict the secure activity resource coordination for secure business processes. We plan to empirically evaluate the SARC artifact against the enhanced Use Case and standard UML activity diagram.
The new unit of competition is no longer the individual firm but rather the extendedenterprise. I... more The new unit of competition is no longer the individual firm but rather the extendedenterprise. It has long been recognized that information security and system integration are among the key issues for IT executives. We posit that these issues still remain open and they are exacerbated by the fact that highly competitive enterprises operate in an environment characterized by distributed and heterogeneous information systems and heterogeneous information and knowledge resources. Following the design science ...
China has seen the most rapid growth in the development of mobile communications in the world. Ma... more China has seen the most rapid growth in the development of mobile communications in the world. Many existing mobile users have an established comfort level with mobile device functionality. This may alleviate their reluctance to conduct mobile commerce (m-commerce) activities. Thus, m-commerce has a potentially exceptional future in China. However, technology development is seriously challenged when users are slow to make decision to adopt the new technology. Enhanced functionality and greater levels of mobile services require an in-depth understanding of consumer characteristics and behavior. Corporations continue to evaluate how individual products and services should be offered for specific consumer groups based on their individual characteristics. To the best of the author's knowledge, little work has been directed at understanding m-commerce users in china. More specifically, the intention to use specific mcommerce services for a variety of demographic bases needed for effective market segmentation and generating value for the Chinese M-commerce user remains largely unstudied. This study investigates the consumers' intention to perform various m-commerce activities and provide valuable insights for effective strategic market segmentation to create value for M-commerce in China. The results provide managers of m-commerce services, seeking to enter the Chinese marketplace, specific information about the Chinese mcommerce users' intention to use m-commerce services based on various individual characteristics.
Skip to main content: Home; About; FAQ; Editor Login. AIS Electronic Library (AISeL). AIS Electro... more Skip to main content: Home; About; FAQ; Editor Login. AIS Electronic Library (AISeL). AIS Electronic Library (AISeL). < Previous; Next >; Home > Conferences > AMCIS > AMCIS 2004 > 218. AMCIS 2004 Proceedings. Title. Agent enabled composition of Services Bundles for M-Commerce Applications. Authors. Thomas Leary, University of North Carolina at Greensboro A. Salam, University of North Carolina at Greensboro Rahul Singh, University of North Carolina at Greensboro. Recommended Citation. ...
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