Papers by Zeinab Hamzehgardeshi

BMC psychology, May 29, 2024
The relationship between psychological factors and treatment outcomes with assisted reproductive ... more The relationship between psychological factors and treatment outcomes with assisted reproductive technology has sparked considerable debate. This study aims to investigate the emotional risk factors in couples seeking infertility treatment using assisted reproductive technology in Sari, Iran, from 2020 to 2022. This research is a cross-sectional study and emotional risk factors and other related factors were examined using the Persian version of the SCREENIVF demographic, social, and clinical status questionnaire, social, and clinical status questionnaire before using Assisted reproductive technology in 460 infertile couples selected from infertility treatment centers in Sari City, Iran. The samples were randomly selected using a table of random numbers. Data analysis was performed using SPSS version 22 software. The mean age of the male and female participants were 31.70 ± 5.71 and 35.22 ± 5.48, respectively. The results regarding emotional risk factors and other related factors revealed that the variables of remarriage (P = 0.048) and exposure of spouse to emotional risk factors (P = 0.001), history of depression disorder (P = 0.007), and history of anxiety disorder (P = 0.009) were significantly correlated with the exposure of women to emotional risk factors. Furthermore, men's exposure to emotional risk factors was significantly correlated with primary education (P = 0.026) and diploma (P = 0.043) levels, age (P = 0.006), and wife's exposure to emotional risk factors (P = 0.001). By identifying infertile couples who are at risk of emotional risk factors, healthcare professionals can provide appropriate support and interventions to mitigate the emotional challenges associated with infertility. This proactive approach can significantly enhance couples undergoing infertility treatment's well-being and mental health.
Vulvovaginal Candidiasis, Honey, Yogurt, Clotrimazole

Additional file 1 of Diagnostic value of serum HER2 levels in breast cancer: a systematic review and meta-analysis
Additional file 1 Supplementary Fig. 1. PRISMA Flowchart of the study selection procedure. Supple... more Additional file 1 Supplementary Fig. 1. PRISMA Flowchart of the study selection procedure. Supplementary Fig. 2. Quality assessment graph. Supplementary Fig. 3. methodological quality summary. Supplementary Fig. 4. Forest plot for sensitivity analysis of serum-HER2 sensitivity. Supplementary Fig. 5. Forest plot for sensitivity analysis of serum-HER2 specificity. Supplementary Fig. 6. Forest plot for sensitivity analysis of serum-HER2 Positive Predictive Value. Supplementary Fig. 7. Forest plot for sensitivity analysis of serum-HER2 Negative Predictive Value. Supplementary Fig. 8. Forest plot for sensitivity analysis of serum-HER2 Positive Likelihood Ratio. Supplementary Fig. 9. Forest plot for sensitivity analysis of serum-HER2 Negative Likelihood Ratio. Supplementary Fig. 10. Forest plot for sensitivity analysis of serum-HER2 accuracy.
Referee report. For: A comparison of physical activity and nutrition in young women with and without primary dysmenorrhea [version 1; referees: 2 approved, 1 approved with reservations]

Human Reproduction, 2020
STUDY QUESTION Can a core outcome set to standardize outcome selection, collection and reporting ... more STUDY QUESTION Can a core outcome set to standardize outcome selection, collection and reporting across future infertility research be developed? SUMMARY ANSWER A minimum data set, known as a core outcome set, has been developed for randomized controlled trials (RCTs) and systematic reviews evaluating potential treatments for infertility. WHAT IS KNOWN ALREADY Complex issues, including a failure to consider the perspectives of people with fertility problems when selecting outcomes, variations in outcome definitions and the selective reporting of outcomes on the basis of statistical analysis, make the results of infertility research difficult to interpret. STUDY DESIGN, SIZE, DURATION A three-round Delphi survey (372 participants from 41 countries) and consensus development workshop (30 participants from 27 countries). PARTICIPANTS/MATERIALS, SETTING, METHODS Healthcare professionals, researchers and people with fertility problems were brought together in an open and transparent proc...

Iranian Journal of Psychiatry and Behavioral Sciences, 2018
The lack of couples' intimacy is one of the main concerns of experts in the field of psychology a... more The lack of couples' intimacy is one of the main concerns of experts in the field of psychology and counseling. It is one of the most important causes of divorce. The 9th principle of International conference on population and development (ICPD) highlights the support of the family as the main unit of the society. The study aimed to determine the socio-demographic predictors of marital intimacy in couples. Methods: This was a cross-sectional study conducted on 118 couples referring to healthcare settings. A random sampling method was used to recruit the couples. Data were collected using the socio-demographic questionnaire, the Bagarozzi's marital intimacy needs questionnaire, Barton's communication skills questionnaire, the Hazan and Shaver's adult attachment styles (1678) questionnaire, and the interpersonal conflict management style (ICMSI). The collected data were analyzed using inferential and descriptive statistics. Results: A statistically significant positive correlation was found in the mean of marital intimacy between men and women. The predictors of marital intimacy in men were the attachment style and communication skills. The predictors of marital intimacy in women were marital satisfaction, communication skills, and conflict resolution styles. Conclusions: Future interventions to improve marital intimacy in couples should consider the following factors: marital satisfaction, marital conflicts, duration of the marriage, communication skills, conflict resolution styles, and the attachment style. It is noted that counselors should attempt to provide appropriate care for couples with the consideration of the above-mentioned factors influencing their interactions and behaviors.
Passive smoking damaged women’s sexual satisfaction Iranian Journal of Reproductive Medicine (IJRM)2012;10(2 (Suppl. 1)):31-2
ﺔﻴروﻬﻤﺟ، ﻦارﻬﻃ ﻲﻓ ﻦﻴﻘﻬارﻤﻠا ﻦﻴﺑ ﺮﻀاﺤﻠا ﺖﻘوﻠا ﻲﻔو ﺮﻤﻌﻠا ﻦﻣ ﺎﻣ ٍﺖﻘو ﻲﻓ ﺔﺸﻴﺸﻠا ﻦﻴﺨدﺗ ﺔﻴﻤاﻠﺴإﻠا ﻦارﻴإ
Etiology of acute bacterial meningitis in hospitalized children in western Uttar Pradesh
Indian pediatrics, 2011
We retrospectively studied clinical and etiological profile of acute bacterial meningitis in hosp... more We retrospectively studied clinical and etiological profile of acute bacterial meningitis in hospitalized children for two consecutive years at a pediatric hospital in western Uttar Pradesh. Etiological diagnosis could be made in 30 (44.8%) out of 67 cases with either culture or latex agglutination test. Pneumococcus was the commonest pathogen found in 17 (25.4%) cases. The overall mortality was 10.5%.

Reproductive health, Apr 17, 2024
Background Sexual health literacy (SHL) leads to the development of personal ability, understandi... more Background Sexual health literacy (SHL) leads to the development of personal ability, understanding, evaluation and use of information related to sexual health. The purpose of this study was to assess the sexual health literacy level and its related factors among married college students at Mazandaran University of Medical Sciences (MAZUMS). Methods A web-based cross-sectional online study was conducted on married college students at Mazandaran University of Medical Sciences between January and November 2020. All students were included in the study by census, and the study method was explained by telephone. If they agreed to participate in the study, the online link to the questionnaire, including sociodemographic and clinical information and Sexual Health Literacy for Iranian Adults (SHELIA), was emailed. The Statistical Package for the Social Sciences (SPSS) software version 26 was used for data analysis. Univariate and multivariate logistic regression tests were used to assess factors related to sexual health literacy. The sample consisted of 277 male and 123 female students. Sexual Health Literacy Level and all subscales are at the sufficient level (66.1-88). Among the participants, 20.5% had limited sexual health literacy. Multivariate analysis found factors related to sexual health literacy among students: economic status (OR 0.03; 95% CI 0.0-0.55) and faculty (OR 0.07; 95% CI 0.01-0.52) is related to decrease and subscription to social media for sexual health (OR 3.27; 95% CI 1.53-7.01), information source of channels and cyberspace (OR 3.23; educational level (OR 16.39;, Internet search information source (OR 1.91; 95% CI 1.00-3.64) is related to increase, were statistically significant factors. In Iran, medical sciences college students, who constitute a significant portion of the country's population, are responsible for sexual health education. Government agencies, with the collaboration of all stakeholders, should develop policies and programs for implementing and evaluating integrated and comprehensive sexual health literacy promotion programs for them.

The role of social capital on unwillingness toward childbearing in reproductive-aged women
Journal of nursing and midwifery sciences, 2022
Context: Although Middle-east is a region with high population growth, but in some countries such... more Context: Although Middle-east is a region with high population growth, but in some countries such as Iran, the population growth significantly decreased rapidly. Social capital is an important factor in formatting the positive willingness of childbearing among couples. Social capital referred to resources that individuals access them through the personal relationships. Aims: This study aimed to investigate the role of social capital on unwillingness toward childbearing in reproductive-aged women referred to Babol Health Care Centers in 2018. Setting and Design: A cross-sectional study in Babol Health Centers, Iran, in 2018. Materials and Methods: Three hundred reproductive-aged women 18–39 years with maximum of two children were recruited through a systematic sampling method. Demographic fertility characteristics form, Miller's childbearing motivation questionnaire, Onyx, and Bullen social capital questionnaire were used for the data collection. Statistical Analysis Used: Descriptive statistics such as frequency, mean ± standard deviation, the Pearson correlation coefficient, and multiple regression were used for the data analysis. Results: The most reasons of unwillingness for childbearing included “worrying about the health and safety of my child,” (83%) “being responsible for a needy and demanding baby,” (78.8%) and “worrying whether I am raising my child the right way.” (77%) Unwillingness to childbearing was associated with the factors such as social capital (β = −0.259, P = 0.001), being employed (β = 0.207, P = 0.001), and well self-evaluation of socioeconomic status (β = −0.187, P = 0.004). Conclusions: Improving the current conditions of childbearing in the Iranian society requires the involvement of policy-makers in the various domains and levels of decision-making at the family, community, and macrolevels.

Clinical Excellence, Nov 10, 2017
Long-term care for people with chronic illness and disability is a very important issue worldwide... more Long-term care for people with chronic illness and disability is a very important issue worldwide. Today, HIV/AIDS is one of the challenges in long-term care. Therefore, the present study aimed to review the barriers and facilitators of self-care in caregiving of HIV/AIDS patients. This study is a narrative review. In order to complete this article, researchers conducted computer search with keywords in databases such as Google scholar, SID, Iranmedex, Medline, PubMed, Springer, Science Direct, ProQuest. Finally, a complete overview of 36 articles has been used to write this article. The findings of this review study led to the classification of materials in two general categories and three sub-classes. 1. Self-care impediments to caregivers of HIV/AIDS patients including individual barriers, interpersonal relationships and barriers Organizational; and 2. Self-care facilitators in caregivers of HIV/AIDS patients, including individual facilitators, interpersonal and organizational facilitator. Be the current review findings suggest that taking care of people living with HIV / AIDS patients often causes great stress and disappointment. As a result, it is necessary to take into account the needs of this group of caregivers and the impact of care on their physical and mental health, and, with a greater understanding of these individuals, a strong foundation for the development of effective interventions such as education, social support, home-based visit planning can be provided.

International journal of adolescent medicine and health, Jun 9, 2017
Background: Intentional injuries refer to injuries resulting from purposeful human action, whethe... more Background: Intentional injuries refer to injuries resulting from purposeful human action, whether directed at oneself or others. This study was performed to assess intentional injuries in Iranian university students. Methods: This cross-sectional study was carried out with 430 female and male university in three higher education institutions located in the northern part of Iran in the year 2015. Samples were chosen through the stratified cluster random sampling method. They were requested to fill out the demographic data form and the Persian version of the Youth Risk Behavior Survey Questionnaire. Descriptive and inferential statistics were used for data analysis via the SPSS v.13 software. Findings: Intentional injuries were more frequent in the male university students than female (p < 0.05). Also, 9.1% and 6.7% of the university students were physically injured or sexually assaulted by a boy/girl friend. No statistically significant difference was reported in dating violence between the male and female university students. The logistic regression test showed that the history of stealing money from parents without their permission, son's preferences in the family and gender are the most important predisposing factors for the university students' intentional injury. Conclusion: It is suggested that health policy makers consider the role of family in programs that have been designed for improving the health of young people.

Internal medicine and medical investigation journal, Oct 31, 2018
Introduction: Health-promoting behavior increases the self-care of the individuals and improves t... more Introduction: Health-promoting behavior increases the self-care of the individuals and improves the health. It reduces the chance of maternal and fetal harm during pregnancy. The objective of this study was to determine the sociodemographic factors related to health-promoting self-care behavior in Iranian pregnant women categorized by domains. Materials and Methods: A crosssectional study design with convenience sampling was used to recruit 384 pregnant Iranian women that were referred to the health center in Sari in 2014-2015. Self-reporting questionnaires included sociodemographic characteristics and health-promoting lifestyle profile-II questionnaires. Data were analyzed with using the statistical package for the social sciences software (version19). One-way ANOVA and chi-square tests were used to determine the relationship between the sociodemographic characteristics and health-promoting behaviors. Results: The mean age of pregnant women was 27.65±4.753 years. Most of the participants were in the second trimester of pregnancy. The mean of the total score for health-promoting behaviors was 142.96±17.947. Among the six dimensions of health-promoting behaviors, the interpersonal relations scored maximal, and the physical activity scored the lowest. Significant correlations existed between spirituality and the wife's education, the wife's job, and the family income. In addition, a significant correlation was established between stress management and the wife's education, also between the aspect of relationships and the husband's education, the wife's education, the family income, and the decision maker (all P<0.005). Conclusion: The findings of the present study confirmed that the sociodemographic factors were vital in health-promoting behaviors in pregnant women.

Psychometric properties of the persian version of the youth risk behavior survey questionnaire
PubMed, Jun 1, 2012
Background: Adolescents may get involved in high-risk behaviors. Surveys are the primary, and som... more Background: Adolescents may get involved in high-risk behaviors. Surveys are the primary, and sometimes the sole source of data collection for many high-risk health behaviours. We examined the reliability and validity of the psychometric properties of the self-administered Persian version of the 2009 Youth Risk Behavior Surveillance System (YRBSS) questionnaire. Methods: In a methodological study in summer 2010, 100 Iranian adolescents aged 15-18 years were recruited through convenience sampling. The face and content validity were used for the questionnaire validity. In order to evaluate the questionnaire's reliability, the Intraclass Correlation Coefficient (ICC) and Cronbach's α were calculated for domains and 89 items. Results: Among 89 items, the ICC values were below 0.4 (weak reliability) for 2 items (2.25%), 0.4-0.6 (moderate reliability) for 10 items (11.24%), 0.6-0.8 (good reliability) for 32 items (35.96%) and 0.8-1 (excellent reliability) for 45 items (50.56%). The prevalence of most high-risk behaviors was constant in the first and second survey. The value of Cronbach's α was 0.73 for intentional and unintentional injuries, 0.77 for tobacco use, 0.86 for alcohol and other drug use, and 0.79 for unsafe sexual behaviors. No domain had a mean ICC of below 0.6. Furthermore, 97.75% of the items had moderate to excellent reliability. Thus, the Persian YRBSS questionnaire had an acceptable reliability. Conclusion: Over the 2-week period, sexual behaviors were reported with less consistency compared to other behaviors. In any case, researchers must be aware of the limitation of the data collected through this questionnaire, particularly in comparison to the domain of sexual behaviors. Overall, 97.75% of the items had moderate to excellent reliability. Thus, the Persian YRBSS questionnaire had an acceptable reliability.
European Psychiatry, Apr 1, 2021

Diagnostic value of serum HER-2 level in compression with tissue HER-2 in breast cancer: A systematic review and meta-analysis
Annals of Oncology, Nov 1, 2019
Abstract Background Measurement of serum human epidermal growth factor receptor-2 (HER-2/neu) lev... more Abstract Background Measurement of serum human epidermal growth factor receptor-2 (HER-2/neu) levels for breast cancer is still controversial and not recommended in any clinical procedures. However, it seems that HER-2 measuring can plays an important role as a diagnostic marker for early selection of therapeutic approach as well as predict of prognosis in breast cancer patients. We aimed to undertake a systematic review and meta-analysis focuses on the diagnostic value of serum HER-2 level measures by ELISA in compare to other methods due to its ease of implementation and cost-effectiveness for HER-2 positive two plus in IHC. Methods We performed a systematic search via PubMed, Scopus, Cochrane Library and Web of Science databases for human diagnostic studies reported the levels of serum HER2 in breast cancer patients, which was confirmed using histopathological examination such as immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). Meta-analyses were carried out for sensitivity, specificity, accuracy, positive predictive value (PPV), negative predictive value (NPV), positive likelihood ratio (PLR) and negative likelihood ratio (NLR). Results Fourteen studies entered into the study. The meta-analysis indicated that serum HER2 levels had sensitivity 53.05 (95%CI 40.82-65.28), specificity 79.27 (95%CI 73.02-85.51), accuracy 72.06 (95%CI 67.04-77.08), PPV 56.18 (95%CI 44.16-68.20), NPV 76.93 (95%CI 69.56-84.31), PLR 2.10 (95%CI 1.69-2.50) and NLR 0.58 (95%CI 0.44-0.71). Conclusions Our findings revealed that, although serum HER2 levels showed a low sensitivity for breast cancer diagnosis, its specificity is significantly high in this regard. Hence, it seems that measurement of serum HER2 levels can play a significant role as a verification test for initial negative screening test results, especially in low-income regions due to its cost-effectiveness and ease of implementation in comparison with monitoring of tissue HER-2. Legal entity responsible for the study Amir Shamshirian and Reza Alizadeh-Navaei. Funding Has not received any funding. Disclosure All authors have declared no conflicts of interest.

Iranian Red Crescent Medical Journal, Apr 5, 2014
Background: Domestic violence refers to any type of physical, sexual, and psychological abuse enf... more Background: Domestic violence refers to any type of physical, sexual, and psychological abuse enforced in the setting of familial relationships. Domestic violence has a significant relationship with poor outcome among pregnant women. Success in resolving this social phenomenon rests on accurate assessment of the society and the factors associated with violence in that specific community. Objectives: The present study was conducted to assess the demographic characteristics of pregnant women exposed to different types of domestic violence during pregnancy in Iranian setting. Patients and Methods: This is a descriptive-analytic, cross-sectional study. Sampling was done with convenience sampling method. in the current study, 301 pregnant women aged 15-45 years of Iranian nationality who were referred to the hospital for delivery or abortion, regardless of the gestational age, were selected as the subjects. Data collection tools consisted of a sociodemographic questionnaire and a violence checklist. Violence was assessed using Revised Conflict Tactics Scale (CTS2). Data were analyzed using descriptive and analytic statistics on SPSS version 16 (SPSS, Chicago, IL, USA) and STATA version 10. The characteristics of the participants were presented as mean ± SD or number and percentage. Differences between variables were determined by the χ2 test, and multivariate logistic regression. P < 0.05 was considered significant. Results: According to the findings, 34.56% of participants had experienced psychological violence, 28.24% physical violence, and 3.65% sexual violence. Multivariate logistic regression revealed a statistically significant relationship only in the case of physical violence and history of penal conviction for partner (Adjusted Odds Ratio (AOR) = 12.60) and a patriarchal household (AOR = 16.75). Conclusions: As domestic violence is greatly influenced by the customs and cultures of each community, no single strategy can be adopted to resolve it universally. Simultaneously, it is necessary to adopt comprehensive measures to control factors associated with domestic violence in the healthcare, judiciary, and the educational systems in order to prevent and curb this social challenge.
Complex factors related to marital and sexual satisfaction among couples undergoing infertility treatment: A cross-sectional study
Heliyon, Apr 1, 2023

Research Square (Research Square), Jul 27, 2022
Objective: Sexual Quality Of Life (SQOL) is an important dimension of women's quality of life and... more Objective: Sexual Quality Of Life (SQOL) is an important dimension of women's quality of life and several factors affect it. In this study, the relationship between SQOL with sexual function and sexual distress of clinical married employed women was investigated Methods: The present study is a cross-sectional study that was performed on 385 clinical married employed women in hospitals of Tehran city Universities of Medical Sciences, using multi-stage sampling method during 2018. The research instruments include demographic information questionnaire, standardized Persian versions of female sexual function, female sexual distress scale, SQOL-F and Beck depression questionnaires and a researcher-made questionnaire of factors related to SQOL. The study data were analyzed using SPSS18 statistical software and the application of independent t-test, one-way ANOVA, chi-square and multiple linear regression. Results: 43.4% and 41.8% of the participants respectively had poor quality of sexual life and high sexual distress; While 64.7% of them had low sexual function. The variables of job type, education (postgraduate, bachelor's and master's degree) and domains of desire, satisfaction and pain in FSFI, total sexual function score and sexual distress score, were related factors to SQOL score. Conclusions: The majority of subjects in this study had good sexual quality of life but low sexual function, so the sexual quality of life in women can be affected by various factors (not just sexual function).
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Papers by Zeinab Hamzehgardeshi