The National Institutes of Health (NIH) has been the stalwart of research funding at universities... more The National Institutes of Health (NIH) has been the stalwart of research funding at universities and academic teaching hospitals. However, since the start of the last decade NIH funding has contracted in real terms. Anticipating future Federal Government fiscal austerity, the situation appears unlikely to improve and most likely will become worse. Local area teaching hospitals have explored other funding to support their large research infrastructure such as industrysponsored research. This thesis qualitatively assessed whether the Federal Government and local area academic hospital fiscal data over the last six years support the hypothesis: Yes, industry funding has been received to support research at local area teaching hospitals to substitute for decreased availability of NIH funds. Biomedical technologies not only offer a new career but also an opportunity to improve lives of people around the world. Having spent many months in remote regions of the world, I have witnessed abject poverty and suffering. When I began my three years in the Biomedical Enterprise Program, I envisioned my goal was to learn all that could be learned to apply my knowledge to increasing access to healthcare. I selected this topic because research, whether government or industry sponsored is the engine that drives innovation. Innovation is the means to improving both healthcare quality and healthcare delivery. I want to express my gratitude and appreciation for my thesis advisors, Prof. Teo Dagi and Prof. Jeffrey Karp, who helped define my thesis. I also want to thank everyone who has made the Biomedical Enterprise Program a transformational period in my life. Being fortunate to have access to MIT, Harvard Medical School, Massachusetts General Hospital, and Harvard Business School throughout the last three years, has enabled me to learn from some of the most gifted, dedicated people in the field of medicine, science, and business. I would like to specifically acknowledge the following people who have been instrumental in my learning and growth, Prof.
Magnetic resonance imaging of the lumbar spine. A comparison with computed tomography and myelography
PubMed, 1986
Two hundred and fifty patients were referred for magnetic resonance imaging (MRI) of the lumbar s... more Two hundred and fifty patients were referred for magnetic resonance imaging (MRI) of the lumbar spine. Computed tomography (CT) and MRI were performed in 50 patients and MRI, CT and myelography in 20 patients. Twenty patients had surgical confirmation of the imaging studies. MRI was best for demonstrating degenerated discs. MRI was better than CT for demonstrating disc bulge without herniation, and MRI was slightly better for herniated disc demonstration than CT. Myelography did not demonstrate degenerated discs.
A history of neurosurgery : in its scientific and professional contexts
American Association of Neurological Surgeons eBooks, 1997
... of Neurosurgery Professor of Medicine University of Virginia Health Sciences Center Charlotte... more ... of Neurosurgery Professor of Medicine University of Virginia Health Sciences Center Charlottesville, Virginia Richard Leblanc, MD, FRCSC ... and Hospital Department of Neurology and Neurosurgery McGill University Montreal, Quebec, Canada Frank P. Saul, PhD, DABFA ...
This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCo... more This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License (www.karger.com/OA-license), applicable to the online version of the article only. Distribution for non-commercial purposes only.
American Journal of Emergency Medicine, Jul 1, 1985
Every year, approximately 9,000 young adults are afflicted by cervical spinal cord injury. They a... more Every year, approximately 9,000 young adults are afflicted by cervical spinal cord injury. They are condemned to an instantaneous and radical alteration in lifestyle that entails an overwhelming physical and emotional adjustment and places a tremendous financial burden on patient, family, and society. To the extent that cervical spinal cord injuries are remediable, constant vigilance is required to protect residual function and prevent secondary damage. For this reason, the present review is directed towards initial emergency management, whose ultimate contribution to the recovery and rehabilitation of the patient with an injured spinal cord is often underestimated. At least one study of an animal model of cervical spinal cord injury has suggested a critical period of four hours during which a partial lesion progresses to completion and intervention may be effective.' Although a human analog of this period has yet to be demonstrated, the general principle that reversible pathological processes are most easily interrupted early in their course is well-established and serves to emphasize the importance of thorough evaluation and careful intervention in the emergency department setting. Cervical spinal cord injuries can occur in the absence of obvious structural damage to the vertebral column, and, conversely, severe structural damage to the vertebral column may spare the spinal cord and cause no obvious neurological impairment. If an unstable spine, however, is not promptly immobilized, the spinal cord may be damaged secondarily. For this reason, an understanding of the anatomical components that insure stability of the cervical spine is paramount to the management of cervical spinal injuries. Recovery from complete, physiological cord trans
Travels to the tropics: Deutschtum and Fedor Krause’s visits to Brazil
Journal of Neurosurgery, Jun 1, 2020
Fedor Krause, the father of German neurosurgery, traveled to Latin America twice in the final yea... more Fedor Krause, the father of German neurosurgery, traveled to Latin America twice in the final years of his career (in 1920 and 1922). The associations and motivations for his travels to South America and his work there have not been well chronicled. In this paper, based on a review of historical official documents and publications, the authors describe Krause’s activities in South America (focusing on Brazil) within the context of the Germanism doctrine and, most importantly, the professional enjoyment Krause reaped from his trips as well as his lasting influence on neurosurgery in South America. Fedor Krause’s visits to Brazil occurred soon after World War I, when Germany sought to reestablish economic, political, cultural, and scientific power and influence. Science, particularly medicine, had been chosen as a field capable of meeting these needs. The advanced German system of academic organization and instruction, which included connections and collaborations with industry, was an optimal means to reestablish the economic viability of not only Germany but also Brazil. Krause, as a de facto ambassador, helped rebuild the German image and reconstruct diplomatic relations between Germany and Brazil. Krause’s interactions during his visits helped put Brazilian neurosurgery on a firm foundation, and he left an indelible legacy of advancing professionalism and specialization in neurosurgery in Brazil.
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Papers by T. Forcht Dagi