Preterm birth is the most important cause of neonatal mortality and morbidity. Finding the best t... more Preterm birth is the most important cause of neonatal mortality and morbidity. Finding the best treatment regimen of antenatal corticosteroids, in order to reduce neonatal complications, has been under serious concern.Objective:The purpose of the present study was to compare the efficacy of intravascular (IV) versus intra muscular (IM) betamethasone phosphate on neonatal outcomes in the cases of imminent preterm birth.Method:The study was conducted as a double-blind randomized clinical trial. 136 pregnant women with gestational age of 26- 34 weeks of pregnancy and imminent preterm birth (delivery within 24 hours) were randomly assigned into two groups. Group A received intramuscular betamethasone phosphate as a dose of 12 mg, and group B received a similar dose of betamethasone phosphate intravenously. Women were followed up to delivery, and their neonatal outcomes were compared.Results:The women of the two groups (68 women in each group), did not show a significant difference in ma...
Tehran University Medical Journal TUMS Publications, 2016
garding the importance and timing of fertility preservation by giving an estimated window of fert... more garding the importance and timing of fertility preservation by giving an estimated window of fertility. The objectives of the current review are to report on the etiology of POF induced through cancer therapy.
Tehran University Medical Journal TUMS Publications, 2016
Conclusion: Overall, this study showed a good sensitivity and specificity for detecting invasion ... more Conclusion: Overall, this study showed a good sensitivity and specificity for detecting invasion into the bladder, vagina, pelvic wall and parameters and good specificity for the diagnosis of rectal invasion and acceptable accuracy at 67.5% for detection of tumor stage by MRI show.
Journal of Obstetrics, Gynecology and Cancer Research, 2017
Introduction: Pseudoaneurysm of the uterine arteries is a rare cause of late postpartum hemorrhag... more Introduction: Pseudoaneurysm of the uterine arteries is a rare cause of late postpartum hemorrhage (PPH) but could potentially be a life threatening complication. Case Presentation: We report a case of a patient with pseudoaneurysm of the uterine arteries following a cesarean section, who presented with late PPH. Bilateral uterine artery ligation was done to conserve the uterus, however, the hemorrhage did not cease. In order to control the bleeding, embolization was suggested. During angiography, a pseudoaneurysm of the feeding femoral artery was noticed and embolization was performed to save the patient. Discussion: Uterine artery pseudoaneurysm is one of the uncommon causes of secondary postpartum hemorrhage and could lead to a life-threatening situation. Management should be multidisciplinary and the gold standard for treatment and diagnosis is through interventional radiology.
Journal of Obstetrics, Gynecology and Cancer Research, 2016
Background: Different studies found that zinc is necessary for sexual maturity, growth and fertil... more Background: Different studies found that zinc is necessary for sexual maturity, growth and fertility. But there are no distinct studies that clarify the role of zinc supplements on semen parameters. Objectives: The current study aimed to evaluate the zinc supplement therapeutic effects on semen samples of infertile males. Patients and Methods: The study comprised one-hundred-twenty sub fertile males. The study was a double-blinded placebocontrolled clinical trial. The subjects were randomly allocated to treatment with zinc supplement (n = 60) or placebo (n = 60) groups. Subjects in both groups were given 10 mL, three times daily. In order to determine the sperm concentration, Motility and morphology, standardized semen and blood samples were obtained before and after treatment, according to the World Health Organization (WHO) guidelines; semen morphology according to strict criteria, and blood and semen zinc concentration also were measured. Effects of the two interventions were evaluated in sub fertile males. Results: Sub fertile males demonstrated a significant increase (8.8 ± 7.4 × 10 6 cells/mL to 17.2 ± 13.5 × 10 6 cells/mL) in concentration and normal sperm in zinc group versus the placebo group. Blood serum zinc concentration increased in the interventional group significantly (P = 0.000), and also semen plasma zinc concentration increased significantly (P = 0.000). Conclusions: Normal sperm percentage and total sperm concentration increased after zinc sulfate treatment. The beneficial effect of zinc and all results of the current study opened new way to medical purposes and public health researches.
International Journal of Research in Medical Sciences, 2015
Surveys around the world have shown that asthma prevalence is highest in industrialized nations. ... more Surveys around the world have shown that asthma prevalence is highest in industrialized nations. 1 Although there is a trend for increased prevalence of asthma in countries farthest from the equator, this disease is common in some tropical countries (e.g., Costa Rica). 1 Epidemiologic data has shown an association between vitamin D deficiency and asthma incidence. 2-5 In fact, sufficient prenatal vitamin D intake may reduce childhood asthma risk up to 40%. 6 Increased asthma severity in older children has been linked to low vitamin D levels. 6,7 Higher maternal intake of vitamin D during pregnancy is associated with a lower risk of recurrent wheezing in young children. 8,11 Although it was believed earlier that vitamin D deficiency was eradicated with fortification of foods, this problem has reappeared and is associated with many disorders. 9 Despite food fortification, multiple studies have shown that vitamin D deficiency is highly prevalent even in sunlight-replete areas of the world and that vitamin D supplementation and fortification of foods ABSTRACT Background: Vitamin D plays an important role in many immune and allergic diseases, and its deficiency is more in areas with low solar radiation. Asthma is a common disease in children of Ardabil city. The present study was designed to evaluate vitamin D levels in asthmatic children in Ardabil. Methods: A total of 100 asthmatic children (40% boys and 60% girls) with a mean age of 5.7 ± 3.46 years (1-15 years) and who visited the Bou-Ali pediatric hospital were included. Vitamin D levels, disease course, IgE levels, and eosinophil counts were evaluated. A group of healthy children was also included to compare vitamin D levels between asthmatic and non-asthmatic children. All data were analyzed by statistical methods in SPSS v.16. Results: The vitamin D levels in asthmatic children were lower than those in the healthy group. Furthermore, the increase in the vitamin D level was significantly associated with lower history of hospitalization (P = 0.02), better response to bronchodilator treatment (P = 0.01), lower IgE level (P = 0.02), and decrease in the mean age of children (P = 0.04). However, no significant association between vitamin D levels and sex (P = 0.08), history of antiinflammatory drug use (P = 0.78), and eosinophil count (P = 0.08) was observed in asthmatic children. Conclusion: Results showed that vitamin D deficiency was more common in asthmatic than in non-asthmatic children and the level of vitamin D was directly associated with the response of the children to treatment.
Uploads
Papers by Sara Norouzi