Two cases of orthotopic ovarian transplantations were performed on patients diagnosed to have Tur... more Two cases of orthotopic ovarian transplantations were performed on patients diagnosed to have Turner's syndrome (ovarian dysgenesis) with primary amenorrhea, short stature, and absent secondary sexual characters. Chromosomal analysis showed 45XO pattern. Both transplants were living related from a sister and from a mother. In both the cases the donor and the recipient were immunologically matched by blood group, histocompatibility antigens (HLA), and lymphocyte cross-match done twice. The donor ovaries were dissected extraperitoneally to have long vascular pedicles. In the first case the donor ovarian vein was sutured end-to-side to external iliac vein and the ovarian artery was sutured to the inferior epigastric artery end-to-end using an operative microscope. The ovary was placed in the orthotopic position transperitoneally. Follow-up for 2.5 years has shown regular menstruations, documented ovulations, rise in hormonal levels, and development of secondary sexual characters. In the second case there was no large vein available for anastomosis so that an avascular orthotopic transplantation was performed. The ovarian cortex was dissected in a fan-shaped manner of 0.5-cm strips. Two grafts sutured onto surgicel were placed orthotopically in the ovarian fossa and the remaining ones were placed into the broad ligament. One month follow-up shows good take-up and follicular development on USG, power-angio, and MRI. Hormonal rise has indicated functioning graft. Immunosuppression was achieved in both cases using cyclosporine (4 mg/kg) and prednisolone (2 mg/kg).
Hurricanes Katrina and Rita struck the Gulf Coast forcing unprecedented mass evacuation and devas... more Hurricanes Katrina and Rita struck the Gulf Coast forcing unprecedented mass evacuation and devastation. Texas 2-1-1 is a disaster communication hub between callers with unmet needs and community services at disaster sites and evacuation destinations. To describe the location and timing of unmet disaster needs collected in real-time through Katrina-Rita disaster phases. In 2008-2010, a total of 25 data sets of Texas 2-1-1 calls from August-December 2005 were recoded and merged. In 2011-2012, analysis was performed of unmet need types, with comparisons over time and location; mapping was adjusted by population size. Of 635,983 total 2-1-1 calls during the study period, 65% included primary disaster unmet needs: housing/shelter (28%); health/safety (18%); food/water (15%); transportation/fuel (4%). Caller demand spiked on Mondays, decreasing to a precipitous drop on weekends and holidays. Unmet needs surged during evacuation and immediate disaster response, remaining at higher threshold through recovery. Unmet need volume was concentrated in metropolitan areas. After adjusting for population size, "hot-spots" showed in smaller evacuation destinations and along evacuation routes. New disaster management strategies and policies are needed for evacuation destinations to support extended evacuation and temporary or permanent relocation. Planning and monitoring disaster resources for unmet needs over time and location could be targeted effectively using real-time 2-1-1 call patterns. Smaller evacuation communities were more vulnerable, exhausting their limited resources more quickly. Emergency managers should devise systems to more quickly authorize vouchers and reimbursements. As 2-1-1s expand and coordinate disaster roles nationwide, opportunities exist for analysis of unmet disaster needs to improve disaster management and enhance community resiliency.
New regional growth may perpetuate social and economic inequalities caused by uneven urban develo... more New regional growth may perpetuate social and economic inequalities caused by uneven urban development, or may reverse such trends by expanding housing options that make possible the dispersal of lower-income households among suburban areas offering better social, economic, and educational opportunities. Supply-side housing approaches can facilitate a more equitable redistribution of housing options. In this research, we examine the role of the Low-Income Housing Tax Credit (LIHTC) program in expanding the geography of opportunity in one fast-growing region-the Dallas/Fort Worth Metroplex. Findings suggest that although LIHTC developments are penetrating the suburbs, they are not expanding opportunities for these households. Just under half of LIHTC units are found in highly clustered areas characterized by high poverty rates, minority concentrations, poor educational opportunities, and rampant crime. The remaining units are dispersed in areas with moderate conditions. Suggestions are made for altering program guidelines to achieve better dispersal, income-mixing, and regionwide distribution.
New regional growth may perpetuate social and economic inequalities caused by uneven urban develo... more New regional growth may perpetuate social and economic inequalities caused by uneven urban development, or may reverse such trends by expanding housing options that make possible the dispersal of lower-income households among suburban areas offering better social, economic, and educational opportunities. Supply-side housing approaches can facilitate a more equitable redistribution of housing options. In this research, we examine the role of the Low-Income Housing Tax Credit (LIHTC) program in expanding the geography of opportunity in one fast-growing region-the Dallas/Fort Worth Metroplex. Findings suggest that although LIHTC developments are penetrating the suburbs, they are not expanding opportunities for these households. Just under half of LIHTC units are found in highly clustered areas characterized by high poverty rates, minority concentrations, poor educational opportunities, and rampant crime. The remaining units are dispersed in areas with moderate conditions. Suggestions are made for altering program guidelines to achieve better dispersal, income-mixing, and regionwide distribution.
An analysis is made of laminar forced convection in a helical pipe of circular cross-section and ... more An analysis is made of laminar forced convection in a helical pipe of circular cross-section and filled by a porous medium saturated with a fluid, for the case when the curvature and torsion of the pipe are both small. The Darcy model is employed, and boundaries with either uniform flux or uniform temperature are considered. It is found that curvature induces a secondary flow at first order in the parameter e = ja, where j is the curvature and a is the radius of the pipe. On the other hand, the Nusselt number is unchanged to first order in e but is increased at second order, for either set of thermal boundary conditions. The effect of torsion on the velocity appears at second order, but torsion does not affect the Nusselt number at second order.
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Papers by Pratik Mhatre