Papers by Pramod CHHABRANI

International Journal of Medical Science and Public Health, 2013
Background: Candiduria is a common finding in hospitalized patients. The isolation of Candida fro... more Background: Candiduria is a common finding in hospitalized patients. The isolation of Candida from urine is challenging for both clinician and microbiologist as to whether the candiduria represents colonization or, lower or upper urinary tract infection including ascending pyelonephritis and renal candidiasis with sepsis. Although Candida albicans is the major cause of candiduria, non-albicans Candida (NAC) has emerged as an important opportunist pathogen. The NAC spp. are not only well adapted to the urinary tract but also are difficult to eradicate than C. albicans. Aims & Objective: The present study aimed to determine the clinico-mycological profile of candiduria in a tertiary care hospital. Material and Methods: A total of 218 Candida spp. isolated from urine samples were included in the study. Speciation of Candida was done by conventional methods and colony colour on HICHROM Candida agar. Antifungal susceptibility testing of the isolates was performed by disc diffusion method on glucose methylene Mueller-Hinton agar (GM-MH). Results: In both the sexes maximum patients belong to age group >50 years. Urinary catheterization, use of broad spectrum antibiotics and diabetes mellitus were the major risks. Isolation of NAC spp. was more. Maximum resistance was seen to fluconazole. Conclusion: The shift towards the NAC spp. as the causative agent of candiduria has generated the concern. Since several NAC spp. are inherently resistant to common antifungal agents, the rapid identification of Candida isolates upto species level along with its in-vitro antifungal susceptibility pattern is important for treatment and management of candiduria.
Prevalence and Outcome of Imported Adult Malaria Cases Admitted to a Tertiary Hospital in Sharjah, United Arab Emirates: A Five Year Study
International Journal of Infectious Diseases and Therapy
Dental caries is one of the oldest diseases afflicting mankind. It occurs as a result of multiple... more Dental caries is one of the oldest diseases afflicting mankind. It occurs as a result of multiple factors which include genetic predisposition, diet, microorganisms, trace elements, tooth morphology, etc. Prevalence of caries is on the declining trend in the developed countries due to strict formulations & regulations of various oral health related programs. But, in developing countries like India dental caries is still highly prevalent. Mutans group of streptococcci is strongly associated with human dental caries & streptococcal mutans is the major aetiological agent of dental caries among mutans group of streptococci.The aim of the present study is to determine the prevalence of S.mutans in saliva of patients with or without caries.

International Journal of Contemporary Dentistry, Apr 16, 2013
Diabetes mellitus is not a single disease entity, but rather a group of metabolic disorders prima... more Diabetes mellitus is not a single disease entity, but rather a group of metabolic disorders primarily of carbohydrate metabolism sharing the common underlying feature of hyperglycemia. Alterations in lipid and protein metabolism are also seen. The chronic hyperglycemia and attendant metabolic dysregulation may be associated with secondary damage in multiple organ systems, especially the kidneys, eyes, nerves and blood vessel. Hyperglycemia in diabetes results from defects in insulin secretion, insulin action or most commonly both. Diabetes mellitus (DM) is a major concern for dentists as their reaction for acceptance & management procedures demand highly specific and greater attention. The average dental practice that serves 100 patients can expect to encounter 8-10 patients with DM, half of whom are unaware of their condition 1,2 .
Prevalence of Streptococcus Mutans in Saliva Patients with Dental Caries
International Journal of Clinical Dental Science, Apr 21, 2013
Dental caries is one of the oldest diseases afflicting mankind. It occurs as a result of multiple... more Dental caries is one of the oldest diseases afflicting mankind. It occurs as a result of multiple factors which include genetic predisposition, diet, microorganisms, trace elements, tooth morphology, etc. Prevalence of caries is on the declining trend in the developed countries due to strict formulations & regulations of various oral health related programs. But, in developing countries like India dental caries is still highly prevalent. Mutans group of streptococcci is strongly associated with human dental caries & streptococcal mutans is the major aetiological agent of dental caries among mutans group of streptococci.The aim of the present study is to determine the prevalence of S.mutans in saliva of patients with or without caries.
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Papers by Pramod CHHABRANI