Muhammad Tahir

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Papers by Muhammad Tahir

Seismic behaviour of concrete bridge piers with various types of transverse reinforcement

Proceedings of the Institution of Civil Engineers - Structures and Buildings

The Classification of Medicinal Plant Leaves Based on Multispectral and Texture Feature Using Machine Learning Approach

Agronomy

This study proposes the machine learning based classification of medical plant leaves. The total ... more This study proposes the machine learning based classification of medical plant leaves. The total six varieties of medicinal plant leaves-based dataset are collected from the Department of Agriculture, The Islamia University of Bahawalpur, Pakistan. These plants are commonly named in English as (herbal) Tulsi, Peppermint, Bael, Lemon balm, Catnip, and Stevia and scientifically named in Latin as Ocimum sanctum, Mentha balsamea, Aegle marmelos, Melissa officinalis, Nepeta cataria, and Stevia rebaudiana, respectively. The multispectral and digital image dataset are collected via a computer vision laboratory setup. For the preprocessing step, we crop the region of the leaf and transform it into a gray level format. Secondly, we perform a seed intensity-based edge/line detection utilizing Sobel filter and draw five regions of observations. A total of 65 fused features dataset is extracted, being a combination of texture, run-length matrix, and multi-spectral features. For the feature opti...

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Some New Facts about the Unit-Rayleigh Distribution with Applications

Mathematics

The unit-Rayleigh distribution is a one-parameter distribution with support on the unit interval.... more The unit-Rayleigh distribution is a one-parameter distribution with support on the unit interval. It is defined as the so-called unit-Weibull distribution with a shape parameter equal to two. As a particular case among others, it seems that it has not been given special attention. This paper shows that the unit-Rayleigh distribution is much more interesting than it might at first glance, revealing closed-form expressions of important functions, and new desirable properties for application purposes. More precisely, on the theoretical level, we contribute to the following aspects: (i) we bring new characteristics on the form analysis of its main probabilistic and reliability functions, and show that the possible mode has a simple analytical expression, (ii) we prove new stochastic ordering results, (iii) we expose closed-form expressions of the incomplete and probability weighted moments at the basis of various probability functions and measures, (iv) we investigate distributional pro...

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Incorporating Noise Robustness in Speech Command Recognition by Noise Augmentation of Training Data

Sensors

The advent of new devices, technology, machine learning techniques, and the availability of free ... more The advent of new devices, technology, machine learning techniques, and the availability of free large speech corpora results in rapid and accurate speech recognition. In the last two decades, extensive research has been initiated by researchers and different organizations to experiment with new techniques and their applications in speech processing systems. There are several speech command based applications in the area of robotics, IoT, ubiquitous computing, and different human-computer interfaces. Various researchers have worked on enhancing the efficiency of speech command based systems and used the speech command dataset. However, none of them catered to noise in the same. Noise is one of the major challenges in any speech recognition system, as real-time noise is a very versatile and unavoidable factor that affects the performance of speech recognition systems, particularly those that have not learned the noise efficiently. We thoroughly analyse the latest trends in speech rec...

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A certain subclass of meromorphically q-starlike functions associated with the Janowski functions

Journal of Inequalities and Applications

In this paper, the authors introduce a new subclass of meromorphic q-starlike functions which are... more In this paper, the authors introduce a new subclass of meromorphic q-starlike functions which are associated with the Janowski functions. A characterization of meromorphically q-starlike functions associated with the Janowski functions has been obtained when the coefficients in their Laurent series expansion about the origin are all positive. This leads to a study of coefficient estimates, distortion theorems, partial sums, and the radius of starlikeness estimates for this class. It is seen that the class considered demonstrates, in some respects, properties analogous to those possessed by the corresponding class of univalent analytic functions with negative coefficients.

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Some General Classes of q-Starlike Functions Associated with the Janowski Functions

Symmetry

By making use of the concept of basic (or q-) calculus, various families of q-extensions of starl... more By making use of the concept of basic (or q-) calculus, various families of q-extensions of starlike functions of order α in the open unit disk U were introduced and studied from many different viewpoints and perspectives. In this paper, we first investigate the relationship between various known classes of q-starlike functions that are associated with the Janowski functions. We then introduce and study a new subclass of q-starlike functions that involves the Janowski functions. We also derive several properties of such families of q-starlike functions with negative coefficients including (for example) distortion theorems.

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Effects of supplementing various linoleic to α-linolenic acid ratios and vitamin A on production performance and egg characteristics of laying hens during summer months

Journal of Zoological Research

In the present feeding trial, responses of laying hens, kept at high ambient temperature, to vari... more In the present feeding trial, responses of laying hens, kept at high ambient temperature, to various dietary ratios of linoleic acid (LNA) to α-linolenic acid (ALA) and vitamin A levels on performance and egg characteristics were evaluated. A total of 360, 40-wk-old, Leghorn laying hens were fed on diets with various combinations of canola oil and linseed oil to achieve LNA to ALA dietary ratios of 20:1, 10:1, 4:1, 2:1, 1:1 and 1:2, each supplemented with 3000 IU or 10000 IU vitamin A/kg of diet. The diets were fed in a 6×2 factorial Completely Randomized Design that continued for 12 weeks. Feed intake, weight gain, egg production and egg quality traits were recorded during the trial. Decreasing dietary LNA to ALA ratio in the diet affected negatively (P<0.05) on body weight gain and yolk percentage in laying hens. While, feed intake, hen-day and hen-housed egg production, feed conversion ratio (FCR) per dozen of eggs and shell quality remained unaffected (P>0.05) by dietary t...

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Injection practices among practitioners in private medical clinics of Karachi, Pakistan

Eastern Mediterranean Health Journal

The aim of this study was to determine the frequency and determinants of sharps injuries among pr... more The aim of this study was to determine the frequency and determinants of sharps injuries among private health practitioners in slum areas of Karachi, Pakistan. All practitioners with at least 1 year of experience in a private medical clinic were asked to complete a self-administered, structured questionnaire (317/397 responded). Only 7.9% of practitioners were qualified from medical school, 12.3% were registered nurses and 8.8% lacked any professional qualifications. At least 1 sharps injury in the previous 12 months was reported by 26.7%, mostly due to needle recapping. Only 25.2% reported using a new syringe for each patient. In multivariate regression analysis shorter work experience, < 14 years of schooling, > 20 patients per day, administering ≥ 30 injections per day, reuse of syringes and needle recapping after use were significantly associated with sharps injury in the past year. Better awareness and training on standard precautions is needed for private practitioners in slum areas of Karachi.

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Biological and phytochemical studies on Capparis decidua (Forssk) Edgew from Cholistan desert

Natural Product Research

The present work deals with the biological and phytochemical studies on Capparis decidua (Forssk)... more The present work deals with the biological and phytochemical studies on Capparis decidua (Forssk) Edgew from Cholistan desert of Pakistan. Aerial and floral parts of C. decidua were collected and dried under shade. Powdered materials of each part of C. decidua were extracted with methanol separately, followed by phytochemical studies. Hexane fraction of aerial parts of the C. decidua obtained after solvent-solvent extraction was purified through repeated column chromatography by increasing order of polarity. Four compounds were purified and identified as simiarenol (1), lupeol (2), taraxerol (3) and β-sitosterol (4). Simiarenol and lupeol were isolated for the first time from genus Capparis. The structures of these compounds were established by comparing the spectroscopic data (H NMR, C NMR, IR, UV &amp;amp;amp;amp;amp; Mass spectrometry) reported in literature. The structure of 1 was further confirmed by XRD analysis. Anti-bacterial activities of crude methanolic extracts were determined against 13 bacterial strains (MIC 250-1000 μg/mL). α-Glucosidase and urease inhibitory activities of pure compounds were also determined. Compounds 1, 2 and 4 showed α-glucosidase inhibition with IC at 96.12 ± 0.12, 65.28 ± 0.13 and 128.14 ± 0.17 μM, respectively.

Are the real-life outcomes of using aflibercept in diabetic macular oedema comparable to the landmark studies?

Acta ophthalmologica, Jan 27, 2018

Genetic correlations among psychiatric and immune-related phenotypes based on genome-wide association data

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Jan 16, 2018

Individuals with psychiatric disorders have elevated rates of autoimmune comorbidity and altered ... more Individuals with psychiatric disorders have elevated rates of autoimmune comorbidity and altered immune signaling. It is unclear whether these altered immunological states have a shared genetic basis with those psychiatric disorders. The present study sought to use existing summary-level data from previous genome-wide association studies to determine if commonly varying single nucleotide polymorphisms are shared between psychiatric and immune-related phenotypes. We estimated heritability and examined pair-wise genetic correlations using the linkage disequilibrium score regression (LDSC) and heritability estimation from summary statistics methods. Using LDSC, we observed significant genetic correlations between immune-related disorders and several psychiatric disorders, including anorexia nervosa, attention deficit-hyperactivity disorder, bipolar disorder, major depression, obsessive compulsive disorder, schizophrenia, smoking behavior, and Tourette syndrome. Loci significantly media...

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Influences for Gender Disparity in Academic Psychiatry in the United States

Cureus, Jan 22, 2018

Introduction Academic undertakings, including research, lead to career progression. However, the ... more Introduction Academic undertakings, including research, lead to career progression. However, the career paths of female psychiatrists appear to diverge significantly from that of their male counterparts. This article reviews the pervasiveness of the trend of women being less likely to pursue active research in psychiatry. In addition, we examine the correlation between academic rank and research productivity. Methods We searched the American Medical Association's (AMA) Fellowship and Residency Electronic Interactive Database (FREIDA) to identify training programs for psychiatry. A total of 5234 psychiatrists met our inclusion criteria. The gender, academic rank, research work, and h-index of faculty members were compared. The ratio of women reaching senior ranks as compared to men was also calculated. The Scopus database was used to determine the h-index of the individuals included in this study. Data analysis was done with SPSS 22.0 Release 2013 (IBM SPSS Statistics for Windows...

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Pars plana vitrectomy in vitreous hemorrhage with or without Intravitreal Bevacizumab a comparative overview

Pakistan journal of medical sciences

To compare the success in patients having vitreous hemorrhage undergoing pars plana vitrectomy wi... more To compare the success in patients having vitreous hemorrhage undergoing pars plana vitrectomy with or without preoperative intravitreal injection of Bevacizumab. This Randomized controlled trial was conducted at Department of Ophthalmology, Jinnah Postgraduate Medical Centre. Karachi. Duration of study was six months from January 2010 to June 2010. In this study 56 patients of advanced diabetic eye disease were divided into two groups. Patients in Group-A underwent three ports pars plana vitrectomy with preoperative intravitreal injection of Bevacizumab (Avastin) 1.25mg/0.05ml, 3.5mm from the limbus seven days before surgery and in Group-B patients underwent vitrectomy without preoperative intravitreal Bevacizumab (Avastin). Intraoperative bleeding was monitored in both groups and was graded as no bleeding, mild bleeding and severe bleeding. The results were statistically analyzed through computer software SPSS 17. Twenty eight patients in Group-A who were given an injection of int...

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Evaluation of carbon nanotube based copper nanoparticle composite for the efficient detection of agroviruses

Journal of hazardous materials, Mar 5, 2017

We report a biosensor that combines the construction of a three-dimensional nanocomposite with el... more We report a biosensor that combines the construction of a three-dimensional nanocomposite with electrochemical methods for the detection of viruses in plants. This is the first report, where carbon nanotubes are used as a conductive frame to anchor highly electrolytic agglomerates of copper nanoparticles to detect agroviruses. Morphological analysis of nanocomposite revealed the presence of carbon nanotubes having a diameter of 50-100nm with copper nanoparticles of 20-100nm, attached in the form of bunches. This material was applied to assess the infection caused by geminiviruses which are a major threat to the cotton plants in Asian and African countries. The hybridization events were studied by monitoring differential pulse voltammetry signals using methylene blue as a redox indicator. In the presence of target DNA, sensor signals decreased from 7×10-4 to 1×10-4Ampere. The probe exhibited 97.14% selectivity and the detection limit was found to be 0.01ngμL-1. The developed biosenso...

Visual and anatomical outcome of macular hole surgery at a tertiary healthcare facility

Pakistan journal of medical sciences

To assess visual and anatomical outcome of full thickness macular hole (FTMH) surgery with ILM pe... more To assess visual and anatomical outcome of full thickness macular hole (FTMH) surgery with ILM peeling using brilliant blue G dye. Thirty patients who had clinically evident macular hole were selected. Pre-operative Optical Coherence Tomography (OCT) was done. In all cases vitrectomy was performed via 23guage 3 ports pars plana (3PPV) vitrectomy system and Brilliant blue G dye, 0.5ml dye was injected over macula which resulted in light blue stain of ILM and peeling was performed around hole in circular motion and after gas fluid exchange gas tamponade with SF6 was done. Final visual and anatomical outcome was measured as postoperative BCVA and postoperative OCT at three months respectively. Descriptive statistics were computed. Paired t-test was applied. P value≤0.05 were considered as significant. There were 12 male and 18 female patients. The mean age was 57.40±4.76 years. The mean size of macular hole was 452.20±242.33μm. The mean duration of symptoms was 16.73±13.49 weeks. Mean ...

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Comprehensive analysis of GASA family members in the Malus domestica genome: identification, characterization, and their expressions in response to apple flower induction

BMC genomics, Jan 27, 2017

The plant-specific gibberellic acid stimulated Arabidopsis (GASA) gene family is critical for pla... more The plant-specific gibberellic acid stimulated Arabidopsis (GASA) gene family is critical for plant development. However, little is known about these genes, particularly in fruit tree species. We identified 15 putative Arabidopsis thaliana GASA (AtGASA) and 26 apple GASA (MdGASA) genes. The identified genes were then characterized (e.g., chromosomal location, structure, and evolutionary relationships). All of the identified A. thaliana and apple GASA proteins included a conserved GASA domain and exhibited similar characteristics. Specifically, the MdGASA expression levels in various tissues and organs were analyzed based on an online gene expression profile and by qRT-PCR. These genes were more highly expressed in the leaves, buds, and fruits compared with the seeds, roots, and seedlings. MdGASA genes were also responsive to gibberellic acid (GA3) and abscisic acid treatments. Additionally, transcriptome sequencing results revealed seven potential flowering-related MdGASA genes. We ...

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Investigating the potential of multiwalled carbon nanotubes based zinc nanocomposite as a recognition interface towards plant pathogen detection

Journal of Virological Methods

The emergence of nanotechnology has opened new horizons for constructing efficient recognition in... more The emergence of nanotechnology has opened new horizons for constructing efficient recognition interfaces. This is the first report where the potential of a multiwalled carbon nanotube based zinc nanocomposite (MWCNTs-Zn NPs) investigated for the detection of an agricultural pathogen i.e. Chili leaf curl betasatellite (ChLCB). Atomic force microscope analyses revealed the presence of multiwalled carbon nanotubes (MWCNTs) having a diameter of 50-100nm with zinc nanoparticles (Zn-NPs) of 25-500nm. In this system, these bunches of Zn-NPs anchored along the whole lengths of MWCNTs were used for the immobilization of probe DNA strands. The electrochemical performance of DNA biosensor was assessed in the absence and presence of the complementary DNA during cyclic and differential pulse voltammetry scans. Target binding events occurring on the interface surface patterned with single-stranded DNA was quantitatively translated into electrochemical signals due to hybridization process. In the presence of complementary target DNA, as the result of duplex formation, there was a decrease in the peak current from 1.89×10(-04) to 5.84×10(-05)A. The specificity of this electrochemical DNA biosensor was found to be three times as compared to non-complementary DNA. This material structuring technique can be extended to design interfaces for the recognition of the other plant viruses and biomolecules.

CRISPR/Cas9: A Practical Approach in Date Palm Genome Editing

Frontiers in plant science, 2017

The genetic modifications through breeding of crop plants have long been used to improve the yiel... more The genetic modifications through breeding of crop plants have long been used to improve the yield and quality. However, precise genome editing (GE) could be a very useful supplementary tool for improvement of crop plants by targeted genome modifications. Various GE techniques including ZFNs (zinc finger nucleases), TALENs (transcription activator-like effector nucleases), and most recently clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 (CRISPR-associated protein 9)-based approaches have been successfully employed for various crop plants including fruit trees. CRISPR/Cas9-based approaches hold great potential in GE due to their simplicity, competency, and versatility over other GE techniques. However, to the best of our knowledge no such genetic improvement has ever been developed in date palm-an important fruit crop in Oasis agriculture. The applications of CRISPR/Cas9 can be a challenging task in date palm GE due to its large and complex genome, high rate ...

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Machine-learning classification of 22q11.2 deletion syndrome: A diffusion tensor imaging study

NeuroImage. Clinical, 2017

Chromosome 22q11.2 deletion syndrome (22q11.2DS) is a genetic neurodevelopmental syndrome that ha... more Chromosome 22q11.2 deletion syndrome (22q11.2DS) is a genetic neurodevelopmental syndrome that has been studied intensively in order to understand relationships between the genetic microdeletion, brain development, cognitive function, and the emergence of psychiatric symptoms. White matter microstructural abnormalities identified using diffusion tensor imaging methods have been reported to affect a variety of neuroanatomical tracts in 22q11.2DS. In the present study, we sought to combine two discovery-based approaches: (1) white matter query language was used to parcellate the brain's white matter into tracts connecting pairs of 34, bilateral cortical regions and (2) the diffusion imaging characteristics of the resulting tracts were analyzed using a machine-learning method called support vector machine in order to optimize the selection of a set of imaging features that maximally discriminated 22q11.2DS and comparison subjects. With this unique approach, we both confirmed previo...

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Investigating nanohybrid material based on 3D CNTs@Cu nanoparticle composite and imprinted polymer for highly selective detection of chloramphenicol

Journal of hazardous materials, Jan 8, 2017

Nanotechnology holds great promise for the fabrication of versatile materials that can be used as... more Nanotechnology holds great promise for the fabrication of versatile materials that can be used as sensor platforms for the highly selective detection of analytes. In this research article we report a new nanohybrid material, where 3D imprinted nanostructures are constructed. First, copper nanoparticles are deposited on carbon nanotubes and then a hybrid structure is formed by coating molecularly imprinted polymer on 3D CNTs@Cu NPs; and a layer by layer assembly is achieved. SEM and AFM revealed the presence of Cu NPs (100-500nm) anchored along the whole length of CNTs, topped with imprinted layer. This material was applied to fabricate an electrochemical sensor to monitor a model veterinary drug, chloramphenicol. The high electron transfer ability and conductivity of the prepared material produced sensitive response, whereas, molecular imprinting produces selectivity towards drug detection. The sensor responses were found concentration dependent and the detection limit was calculate...

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