Monica Molina

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Actividad antioxidante y contenido total de fenoles de los extractos etanólicos de salvia aratocensis, salvia sochensis, bidens reptons y montanoa ovalifolia

The antioxidant activities (assessed through the DPPH radical decoloration test) and the total co... more The antioxidant activities (assessed through the DPPH radical decoloration test) and the total content of phe nols (determined by means of the Folin-Ciocalteu method), of the etanolic extracts of Salvia aratocensis, Salvia sochensis, Bidens reptans and Montanoa ovalifolia were determined. The corresponding values were: 0,0011 ± 0,0001; 0,00190 ± 0,00005; 0,0016 ± 0.0001 y 0,0073 ± 0.0001 (kg extract/ initial mmol of DPPH . ), and 0,30 ± 0.05; 0,17 ± 0,01; 0,40 ± 0,04, and 0,13 ± 0,01 (mg phenols/100 mg of plant).

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Asset Liability Management in Bank Portfolios with Fuzzy Linear Programming

FUZZY ECONOMIC REVIEW, 2003

In this paper we develop a model of asset liability management for banking companies that maximis... more In this paper we develop a model of asset liability management for banking companies that maximises bank profits and minimises capital requirement in accordance with the Basel Accords. The model is based on fuzzy programming, which we use to solve a bi objective programme with crisp coefficients. Subsequently, we propose a fuzzy programming model that makes it possible to avoid

Causas y efectos de la agricultura ecológica en las cooperativas oleícolas

La Sociedad Cooperativa, 2007

Los afrobrasileños y su lucha por el respeto a su identidad

Utilidad de la ultrasonografía introital en incontinencia de orina de esfuerzo, curva ROC

Rev Chil Ultrason, 2007

Strategies to increase male utilization of family planning: Integrating family planning counseling in a community clinic setting

A needs assessment of prevention services available for incarcerated youth in Los Angeles County

Proyecto de factibilidad para la creación de un complejo turístico en la ciudad de Latacunga, sector Locoa Santa Ana, Provincia de Cotopaxi

2.3.2 Fuentes de información secundarias CONTENIDO 2.4 Tamaño a la población PAG. 2.4.1 Cálculo d... more 2.3.2 Fuentes de información secundarias CONTENIDO 2.4 Tamaño a la población PAG. 2.4.1 Cálculo del tamaño de la muestra 2.4.2 Diseño del cuestionario 2.4.3 Resultado de las encuestas 2.5 Análisis de la demanda 2.5.1 Demanda actual del servicio 2.5.2 Demanda proyectada 2.6 Análisis de la oferta 2.6.1 Oferta actual del servicio 2.6.2 Oferta proyectada 2.7 Demanda insatisfecha 2.8 Análisis del precio 2.8.1 Proyección del precio 2.9 Mezcla de marketing 2.9.1 Estrategia del servicio 2.9.2 Estrategia de distribución (plaza) 2.9.3 Estrategia de promoción 2.9.4 Estrategia de precio CAPÍTULO III 3 Estudio técnico 3.1 Tamaño del proyecto 3.1.1 Capacidad instalada 3.2 Localización 3.2.1 Macro localización 3.2.1.1 Justificación 3.2.2 Micro localización 3.2.3 Análisis de la disponibilidad de recursos 3.2.4 Plano de la micro localización 3.3 Ingeniería del servicio x 3.3.1 Descripción del servicio 82 CONTENIDO 3.3.1.1 Especificaciones del servicio PAG. 82 3.3.1.2 Especificaciones técnicas 87 3.3.1.3 Especificaciones de diseño y calidad del servicio 88 3.3.1.4 Distribución física del complejo turístico 89 3.4 Requerimiento del proyecto 90 CAPÍTULO IV 4 Estudio financiero 98 4.1 Componentes de la inversión 98 4.1.1 Inversión fija 98 4.1.2 Inversión diferida 99 4.2 Capital de trabajo 4.3 Depreciaciones 4.4 Financiamiento 4.4.1 Financiamiento con aporte propio 4.4.2 Financiamiento mediante préstamos 4.5 Programa de inversiones 4.6 Determinación de costos de operación 4.7 Costos anuales proyectados 4.8 Determinación de ingresos 4.8.1 Ingresos anuales proyectados 4.9 Estados financieros 4.10 Estado de pérdidas y ganancias proyectados 4.11 Balance general proforma 4.12 Punto de equilibrio 4.13 Flujo de caja CAPÍTULO V 5 Evaluación financiera 5.1 Costo de oportunidad xi 5.2 Valor actual neto (VAN) CONTENIDO 5.3 Tasa interna de retorno (TIR) PAG. 5.4 Período de recuperación de la inversión (PRI) 5.5 Relación beneficio-costo 5.6 Análisis de los estados financieros 5.6.1 Razones de liquidez 5.6.2 Razones de actividad 5.6.3 Razones de rentabilidad 5.6.4 Razones de endeudamiento 5.7 Impacto del proyecto del nuevo complejo turístico 5.7.1 Impacto socioeconómico 5.7.2 Impacto ambiental CAPÍTULO VI

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Aplicación De Tres Estratégias Metodológicas para mejorar la Lectura Comprensiva y el Aprendizaje Significativo en las estudiantes de Octavo Año De Educación Básica Del Instituto “Victoria Vásconez Cuvi” de la ciudad de Latacunga de la Provincia de Cotopaxi en el período Noviembre 2010 – Marzo 2011

No warning shots: The risks and realities of HIV/AIDS and Hepatitis C in California prisons and other correctional settings

Pentosidine Content in Skin Collagen from Type II Diabetic Patients

Biochemical Society Transactions, 1994

Mortandades en masa producidas por cianobacterias tóxicas en el Parque Nacional de Doñana

The effect of nitrate and phosphate availability on Emiliania huxleyi (NZEH) physiology under different CO2 scenarios

Growth and calcification of the marine coccolithophorid Emiliania huxleyi is affected by ocean ac... more Growth and calcification of the marine coccolithophorid Emiliania huxleyi is affected by ocean acidification and macronutrients limitation and its response varies between strains. Here we investigated the physiological performance of a highly calcified E. huxleyi strain, NZEH, in a multiparametric experiment. Cells were exposed to different CO 2 levels (ranging from 250 to 1314 µatm) under three nutrient conditions [nutrient replete (R), nitrate limited (-N), and phosphate limited (-P)]. We focused on calcite and organic carbon quotas and on nitrate and phosphate utilization by analyzing the activity of nitrate reductase (NRase) and alkaline phosphatase (APase), respectively. Particulate inorganic (PIC) and organic (POC) carbon quotas increased with increasing CO 2 under R conditions but a different pattern was observed under nutrient limitation. The PIC:POC ratio decreased with increasing CO 2 in nutrient limited cultures. Coccolith length increased with CO 2 under all nutrient conditions but the coccosphere volume varied depending on the nutrient treatment. Maximum APase activity was found at 561 µatm of CO 2 (pH 7.92) in-P cultures and in R conditions, NRase activity increased linearly with CO 2. These results suggest that E. huxleyi's competitive ability for nutrient uptake might be altered in future high-CO 2 oceans. The combined dataset will be useful in model parameterizations of the carbon cycle and ocean acidification.

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Behavioural transformation to improve circuit performance in high-level synthesis

Early scheduling algorithms usually adjusted the clock cycle duration to the execution time of th... more Early scheduling algorithms usually adjusted the clock cycle duration to the execution time of the slowest operation. This resulted in large slack times wasted in those cycles executing faster operations. To reduce the wasted times multi-cycle and chaining techniques have been employed. While these techniques have produced successful designs, its effectiveness is often limited due to the area increment that may derive from chaining, and the extra latencies that may derive from multicycling. In this paper we present an optimization method that solves the time-constrained scheduling problem by transforming behavioural specifications into new ones whose subsequent synthesis substantially improves circuit performance. Our proposal breaks up some of the specification operations, allowing their execution during several possibly unconsecutive cycles, and also the calculation of several data-dependent operation fragments in the same cycle. To do so, it takes into account the circuit latency and the execution time of every specification operation. The experimental results carried out show that circuits obtained from the optimized specification are on average 60% faster than those synthesized from the original specification, with only slight increments in the circuit area.

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Effects of adaptation, chance, and history on the evolution of the toxic dinoflagellateAlexandrium minutumunder selection of increased temperature and acidification

Ecology and Evolution, 2012

The roles of adaptation, chance, and history on evolution of the toxic dinoflagellate Alexandrium... more The roles of adaptation, chance, and history on evolution of the toxic dinoflagellate Alexandrium minutum Halim, under selective conditions simulating global change, have been addressed. Two toxic strains (AL1V and AL2V), previously acclimated for two years at pH 8.0 and 20 • C, were transferred to selective conditions: pH 7.5 to simulate acidification and 25 • C. Cultures under selective conditions were propagated until growth rate and toxin cell quota achieved an invariant mean value at 720 days (ca. 250 and ca. 180 generations for strains AL1V and AL2V, respectively). Historical contingencies strongly constrained the evolution of growth rate and toxin cell quota, but the forces involved in the evolution were not the same for both traits. Growth rate was 1.5-1.6 times higher than the one measured in ancestral conditions. Genetic adaptation explained two-thirds of total adaptation while one-third was a consequence of physiological adaptation. On the other hand, the evolution of toxin cell quota showed a pattern attributable to neutral mutations because the final variances were significantly higher than those measured at the start of the experiment. It has been hypothesized that harmful algal blooms will increase under the future scenario of global change. Although this study might be considered an oversimplification of the reality, it can be hypothesized that toxic blooms will increase but no predictions can be advanced about toxicity.

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Falla cardíaca aguda asociada a bloqueo aurículo ventricular congénito completo secundario a lupus neonatal: reporte de una serie de casos

Revista Colombiana de Reumatología, 2010

El lupus neonatal (LN) comprende un conjunto de síndromes clínicos caracterizados por anticuerpos... more El lupus neonatal (LN) comprende un conjunto de síndromes clínicos caracterizados por anticuerpos maternos contra el complejo RNA proteína (Ro/SSA o La/SSB) que atraviesan la placenta y potencialmente llevan a daño tisular fetal. Poco se conoce acerca de otras manifestaciones cardíacas del LN diferentes al bloqueo cardíaco congénito (BCC), como la falla cardíaca (ICC). Se reportan cuatro casos de LN con BCC e ICC aguda en los primeros tres días de vida en promedio. No se presentaron complicaciones o muertes a los 4,9 meses de seguimiento. Todos los neonatos tenían títulos altos de anti-Ro al momento del diagnóstico.

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Warming will affect phytoplankton differently: evidence through a mechanistic approach

Proceedings of the Royal Society B: Biological Sciences, 2011

Although the consequences of global warming in aquatic ecosystems are only beginning to be reveal... more Although the consequences of global warming in aquatic ecosystems are only beginning to be revealed, a key to forecasting the impact on aquatic communities is an understanding of individual species' vulnerability to increased temperature. Despite their microscopic size, phytoplankton support about half of the global primary production, drive essential biogeochemical cycles and represent the basis of the aquatic food web. At present, it is known that phytoplankton are important targets and, consequently, harbingers of climate change in aquatic systems. Therefore, investigating the capacity of phytoplankton to adapt to the predicted warming has become a relevant issue. However, considering the polyphyletic complexity of the phytoplankton community, different responses to increased temperature are expected. We experimentally tested the effects of warming on 12 species of phytoplankton isolated from a variety of environments by using a mechanistic approach able to assess evolutionar...

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The limit of the genetic adaptation to copper in freshwater phytoplankton

Oecologia, 2014

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Evolutionary Changes in Growth Rate and Toxin Production in the Cyanobacterium Microcystis aeruginosa Under a Scenario of Eutrophication and Temperature Increase

Microbial Ecology, 2011

Toxic blooms of the cyanobacterium Microcystis aeruginosa affect humans and animals in inland wat... more Toxic blooms of the cyanobacterium Microcystis aeruginosa affect humans and animals in inland water systems worldwide, and it has been hypothesized that the development of these blooms will increase under the future scenario of global change, considering eutrophication and temperature increase as two important consequences. The importance of genetic adaptation, chance and history on evolution of growth rate, and toxin production of M. aeruginosa was studied under these new conditions. The experiment followed the idea of "replaying life's tape" by means of the simultaneous propagation of 15 independent isolates of three M. aeruginosa strains, which were grown under doubled nutrient concentration and temperature during c. 87 generations. Adaptation by new mutations that resulted in the enhancement of growth rate arose during propagation of derived cultures under the new environmental conditions was the main component of evolution; however, chance also contributed in a lesser extension to evolution of growth rate. Mutations were selected, displacing the wild-type ancestral genotypes. In contrast, the effect of selection on mutations affecting microcystin production was neutral. Chance and history were the pacemakers in evolution of toxin production. Although this study might be considered an oversimplification of the reality, it suggest that a future scenario of global change might lead to an increase in M. aeruginosa bloom frequency, but no predictions about the frequency of toxicity can be made. M. Rouco (*) : V. López-Rodas : E.

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Modelling of aflatoxin production by Aspergillus parasiticus in a solid medium at different temperatures, pH and propionic acid concentrations

Food Research International, 2002

The effect of pH (5.5 and 5.9), propionic acid concentration (129, 258 and 516 ppm) and temperatu... more The effect of pH (5.5 and 5.9), propionic acid concentration (129, 258 and 516 ppm) and temperature (25, 30 and 36 C) on aflatoxin production by Aspergillus parasiticus in solid media at controlled water activity 0.95 was studied. Modelling of aflatoxin production was carried out using adequate equations to obtain the maximum aflatoxin concentration (C values) and the corresponding time to reach the maximum (a values). For control samples, the highest C values were observed for aflatoxin B1 and G1. The effect of temperature on aflatoxin production at different pH was analysed using a function derived from the Arrhenius equation. Optimum temperatures for aflatoxin production were 27.84 and 27.32 C at pH 5.9 and 5.5, respectively. Two indices were defined in order to analyse the effect of undissociated propionic acid concentration (uac) on C and a values. Propionic acid showed the highest inhibition on C values for aflatoxin G1 and on a values for aflatoxin B1. Concentrations over 60 ppm uac did not show an increase in both indices indicating that there is no need to increase the concentration of propionic acid over this value. These plots may be useful for technological purposes and to identify conditions (pH, propionic acid and storage temperature) to inhibit aflatoxin production in foodstuffs.

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