Papers by Michael Chernet
Journal of clinical & experimental oncology, 2013
Cancer may be a disease of geometry: a misregulation of the field of information that orchestrate... more Cancer may be a disease of geometry: a misregulation of the field of information that orchestrates individual cells' activities towards normal anatomy. Recent work identified molecular mechanisms underlying a novel system of developmental control: bioelectric gradients. Endogenous spatio-temporal differences in resting potential of non-neural cells provide instructive cues for cell regulation and complex patterning during embryogenesis and regeneration. It is now appreciated that these cues are an important layer of the dysregulation of cell: cell interactions that leads to cancer. Abnormal depolarization of resting potential (Vmem) is a convenient marker for neoplasia and activates a metastatic phenotype in genetically-normal cells in vivo. Moreover, oncogene expression depolarizes cells that form tumor-like structures, but is unable to form tumors if this depolarization is artificially prevented by misexpression of hyperpolarizing ion channels. Vmem triggers metastatic behavio...
Science, Technology and Arts Research Journal, 2014
Recycling is a strategy to combat environmental pollution due to plastic wastes. Of the many plas... more Recycling is a strategy to combat environmental pollution due to plastic wastes. Of the many plastic wastes, researchers confirmed the possibility to produce plastic lumber from used HDPE plastics. The aim of this study is to experimentally determine the mechanical property of the plastic lumber produced from pure HDPE and its composite with wood to proof usability and applicability for different purpose. The experiment considered different conditions. Pure plastic lumber and wood plastic composite lumber is initially produced and examined under room temperature and below room temperature. Under each condition, bending, tensile and impact strength were examined. For each test eight specimens were prepared based on international standards and the experiments were conducted using standard testing machines. The result shows that pure plastic lumber has demonstrated superior load carrying capability, tensile load resistance capability and impact load resistance at room temperature. Moreover, the pure plastic lumber has an elastic nature and the wood composite has a brittle nature. In both cases the mechanical property of the plastic lumber permits to use for different applications. This has been also tested and resulted in similar phenomena at 2 0 C below room temperature.
Uploads
Papers by Michael Chernet