Melek Demir

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Eğitim Bilimler Bölümü Rehberlik ve Psikolojik Danışma Anabilim dalı Endişelerin Kişilerarası İlişki Boyutları Üzerine Etkisi

Yaşlılık Psikolojisi Bütüncül Yaklaşım

Gluten intolerance antibodies in multiple sclerosis and clinically isolated syndrome : Coexistent or coincidental?

Clinical and Experimental Neuroimmunology, 2021

As it is well known that autoimmune diseases can coexist, the association of multiple sclerosis (... more As it is well known that autoimmune diseases can coexist, the association of multiple sclerosis (MS) with other autoimmune diseases has always been a major concern for clinicians. In this study, we aimed to investigate the clinical findings, and the frequency of autoantibodies related to celiac disease in MS and clinically isolated syndrome (CIS).

The Relationship Between Mindfulness and Cognitive Flexibility of University Students

Yaşam Becerileri Psikoloji Dergisi, 2021

Bu çalışmanın amacı, üniversite öğrencilerinin bilinçli farkındalıkları ile bilişsel esneklikleri... more Bu çalışmanın amacı, üniversite öğrencilerinin bilinçli farkındalıkları ile bilişsel esneklikleri arasındaki ilişkiyi incelemektir. Bu araştırmanın çalışma grubunu 187 kadın ve 57 erkek toplam 244 üniversite öğrencisi oluşturmaktadır. Çalışma grubundaki üniversite öğrencilerinin yaşları 18 ile 34 arasında değişmekte olup, yaş ortalaması 20.27’dir. Veri toplama sürecinde Bilinçli Farkındalık Ölçeği, Bilişsel Esneklik Envanteri ve katılımcıların demografik bilgilerinin toplandığı kişisel bilgi formu kullanılmıştır. Bilinçli farkındalık ile bilişsel esneklik (alternatif ve kontrol) arasındaki ilişkileri belirlemek amacıyla Pearson momentler çarpımı korelasyon katsayıları kullanılmıştır. Korelasyon analizi sonuçlarına göre, bilinçli farkındalık ile bilişsel esneklik ve bilişsel esnekliğin alt boyutları olan alternatif ve kontrol arasında pozitif yönde anlamlı ilişkiler tespit edilmiştir. Bilinçli farkındalık ile bilişsel esneklik arasındaki ilişkinin cinsiyete göre anlamlı bir farklılık...

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The effect of chlorhexidine gluconate and povidone-iodine on Candida albicans

The mediating role of binge-watching in the relationship between type D personality and loneliness

Health Psychology Report, 2021

BackgroundIndividuals who have certain personality traits may be particularly at risk for develop... more BackgroundIndividuals who have certain personality traits may be particularly at risk for developing technological addictions. Binge-watching, which includes watching several episodes of a television series consecutively, is seen as a behavior that is out of control and even addictive. Binge-watching also can isolate the individual socially, or it can be a buffer against the individual’s feeling of loneliness. This study was conducted to examine the mediating role of binge-watching in the relationship between type D personality and loneliness.Participants and procedure570 adults older than 18 years of age who were reached by the convenience sampling method participated in the study. The data were collected with the Type D Personality Scale, UCLA Loneliness Scale, and the Binge-Watching Engagement and Symptoms Questionnaire.ResultsAs a result of the study, binge-watching mediated the relationship between type D personality and loneliness, and fit values of this model were within the ...

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Differential Diagnosis of Recurrent Hypersomnia: A Case Report of Primary Narcolepsy and Acute Transient Psychotic Attack

The Journal of Pediatric Research, 2021

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Cinderella Syndrome "Women with Fear of Independence": Developing a Scale

International Journal of Psychology and Educational Studies, 2021

Cinderella syndrome is a concept which is used to define woman who fear from being independent. W... more Cinderella syndrome is a concept which is used to define woman who fear from being independent. Women with Cinderella syndrome are in the need of men’s refuge and protection. The syndrome is like a psychological dependence for women and in this dependence, situation being patient and moral is important for being rescued by a man as a reward. In the syndrome women expect a man to come and take control of their own lives so that they can live happily. The aim of the study developing a scale into Turkish culture to determine the level of Cinderella Syndrome in females. The Cinderella Syndrome Scale is a 5-point Likert Type scale which includes 25 items. Exploratory factor analysis (EFA) was conducted to define construct validity and three factors were determined, called “sexist attitude”, “escape from responsibility” and “quitting career”. According to EFA, three factors describe 54,69 % of the variance. Results of EFA were validated by confirmatory factor analysis (CFA). The Cronbach...

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İzmir Zeytin Sempozyumu

İzmir Zeytin Sempozyumu, 2017

İzmir'in tarih boyunca en önemli özelliği, bir liman kenti olmasıdır. Bu kent, binlerce yıllık li... more İzmir'in tarih boyunca en önemli özelliği, bir liman kenti olmasıdır. Bu kent, binlerce yıllık liman ve ihracat karakterini halen sürdürüyor. İzmir'e, doğudan veya batıdan kim gelirse gelsin mutlaka bir şey bırakıyor. İzmir'den her gidenlerde, bir şey alıp götürüyor. Aklınıza gelen her konuda, İzmir büyük bir kültür birikimine sahiptir. İzmir Büyükşehir Belediyesi, İzmir'in demokrasi kültürüne uygun yöntemle Ekim 2009'da, İzmir Kültür Çalıştayı'nı topladı. Akademisyen, sanatçı, gazeteci, mimar, tarihçi gibi kendi alanlarında uzman, yüze yakın katılımcıyla gerçekleştirilen tartışmalar sonucunda, İzmir'in vizyonu belirlendi. Kültür Çalıştayı'nın belirlediği, İzmir vizyonunun düşünsel ve örgütsel yükünü üstlenecek kurum olarak da İzmir Büyükşehir Belediyesi'nin, 'İzmir Akdeniz Akademisi' adıyla bir yapı oluşturması gündeme geldi. Yoğun çalışma ve tartışmaların arkasından biçimlenen

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İzmir Ekoloji Forumu

İzmir Ekoloji Forumu, 2015

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Improvement of conformal arc plans by using deformable margin delineation method for stereotactic lung radiotherapy

Journal of applied clinical medical physics, Jan 7, 2017

Stereotactic body radiotherapy (SBRT) is an established treatment technique in the management of ... more Stereotactic body radiotherapy (SBRT) is an established treatment technique in the management of medically inoperable early stage non-small cell lung cancer (NSCLC). Different techniques such as volumetric modulated arc (VMAT) and three-dimensional conformal arc (DCA) can be used in SBRT. Previously, it has been shown that VMAT is superior to DCA technique in terms of plan evaluation parameters. However, DCA technique has several advantages such as ease of use and considerable shortening of the treatment time. DCA technique usually results in worse conformity which is not possible to ameliorate by inverse optimization. In this study, we aimed to analyze whether a simple method - deformable margin delineation (DMD) - improves the quality of the DCA technique, reaching similar results to VMAT in terms of plan evaluation parameters. Twenty stage I-II (T1-2, N0, M0) NSCLC patients were included in this retrospective dosimetric study. Noncoplanar VMAT and conventional DCA plans were gene...

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[Does pre-incubation period affect detection of Pseudomonas aeruginosa and Acinetobacter baumannii species with automatized BACTEC 9120 blood culture system?]

Mikrobiyoloji bülteni, 2006

In this study, the effect of the pre-incubation period on detection of non-fermentative species i... more In this study, the effect of the pre-incubation period on detection of non-fermentative species in blood culture system was investigated. Different concentrations of Pseudomonas aeruginosa and Acinetobacter strains were inoculated into BACTEC-9120 plus+Aerobic/F bottles and incubated for 0, 4, 8, 16 hours at 36 dgerees C and then were loaded to the system. Both P. aeruginosa and A.baumannii strains yielded positive signals within 24 hours after loading. In all preincubation periods, as the concentration of P. aeruginosa strains decreased, the detection time was increased. The higher the concentration of A.baumannii strains, is the longer the signalling time as the pre-incubation period is increased, whereas the lower the concentration of A. baumannii strains, is the shorter the signalling time as the preincubation period is increased. Our study indicated that the BACTEC-9120 blood culture system determined non-fermentative bacteria after a pre-incubation time of 16 hours.

Serum neopterin levels in patients with replicative and nonreplicative HBV carriers

BMC infectious diseases, Jan 31, 2006

Infection by hepatitis B virus (HBV) causes complicated biochemical, immunological and histologic... more Infection by hepatitis B virus (HBV) causes complicated biochemical, immunological and histological changes in host immune response against the virus which can be specific or non-specific. Recent attention has focused on neopterin as a marker for the activation of cell mediated immunity. The aim of this study was to define the pattern of neopterin levels in replicative and nonreplicative HBV carriers. Thirty HBV replicative carriers and 25 nonreplicative HBV carriers and 30 healthy adult patients were included this study. Hepatitis markers were determined by commercial kit based on chemilumminesans assay. HBV DNA was quantified by hybrid capture system. Serum neopterin levels were measured by the method of competitive enzyme-linked immunosorbent assay. Results were expressed as mean +/- SD and ranges. In the nonreplicative group, except for one patient, all the patients' HBeAg were negative and anti-HBe were positive. That particular patient was HBeAg positive and anti-HBe negat...

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Evaluation of biofilm production, gelatinase activity, and mannose-resistant hemagglutination in Acinetobacter baumannii strains

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2008

Acinetobacter baumannii is an important nosocomial pathogen, but its pathogenic characteristics a... more Acinetobacter baumannii is an important nosocomial pathogen, but its pathogenic characteristics are not well defined. The purpose of this study was to evaluate biofilm production, mannose-resistant hemagglutination, and gelatinase production in A. baumannii strains isolated from various clinical specimens. Eighty six strains of A. baumannii isolated from 86 hospital inpatients were studied for biofilm formation, gelatinase activity, and mannose-resistant hemagglutination. The isolates were identified using conventional techniques and/or the API 2ONE system. Comparisons of biofilm production, gelatinase activity, and mannose-resistant hemagglutination were made by chi-squared analysis. Twenty two and 61 of the isolates agglutinated human group O and AB erythrocytes in the presence of mannose, respectively. Gelatinase activity was detected in 12 isolates (14%), while 64 isolates formed biofilms. Several parameters may play important roles in causing infection in colonized patients. Id...

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Are tonsils a reservoir for Helicobacter pylori infection in children?

International Journal of Pediatric Otorhinolaryngology, 2004

Helicobacter pylori (H. Pylori) has been associated with the development of gastritis, peptic ulc... more Helicobacter pylori (H. Pylori) has been associated with the development of gastritis, peptic ulcer and gastric cancer. Although H. pylori infects up to more than half of the world's population, to date the precise modes of transmission has not been fully understood yet. Therefore a study was planned to investigate whether the tonsils and the adenoid tissue were the reservoir or the gate for the entrance of H. pylori. Methods: The adenotonsillectomy specimens obtained from 50 children, between two and 10 years of age were examined for H. Pylori colonization by the CLO-test method. Before tonsillectomy, anti-H. pylori IgG antibody titers were detected by commercial enzyme immunoassay method in venous blood and H. pylori antigen enzyme immunoassay for detection of H. pylori in stool was used to define current infection status. Results: The stool antigen was positive in 25 (50%) of 50 children. Serum IgG antibody was positive in 28 (56%) patients and both tests were positive in 21 (42%) patients. H. pylori positivity was not detected in any one of the adenotonsillectomy specimens with the CLO-test method. Conclusion: In this study although H. pylori was detected in stools of children, it was not detected in adenotonsillectomy specimens with CLO-test method. The results may indicate that H. pylori does not colonize in either adenoid or tonsils and that these tissues do not constitute a reservoir for H. pylori infection.

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[Investigation of the inter-observer agreement rates for morphometric evaluation of the growth of Microsporum canis colonies]

Mikrobiyoloji bülteni, 2004

Morphometry is a newly applied method for investigation of the in-vitro growth dynamics of dermat... more Morphometry is a newly applied method for investigation of the in-vitro growth dynamics of dermatophyte colonies. This study was undertaken to evaluate the correlation and agreement rates between the morphometric data obtained by different observers. For this purpose, five different Microsporum canis growth data were evaluated by six observers. The results of the study suggested that the agreement rates among the data obtained by different observers were low (R1 = -5.3509), while the results obtained by a single observer at different reading time points were consistent and correlated with the estimated growth rate. We thus recommend the evaluation of morphometric test results by a single observer for optimal standardization and consistency.

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