Asian Journal of Pharmaceutical Research and Development, 2019
Depression, tension and mental health have been ignored as a serious issue since ages. Depression... more Depression, tension and mental health have been ignored as a serious issue since ages. Depression can be fatal or life-threatening, if not treated to this problem. Antidepressants are also regularly used to treat many other conditions, such as social phobia, fibromyalgia, panic disorder, anxiety/anxiety depression, PTSD, OCD, PMDD, and menopause. The major antidepressant used in the study followed oral prescribing trends. A “serious adverse reaction means an adverse reaction which is fatal, life-threatening, disabling, incapacitating, or which results in or prolongs hospitalization.” Material method collect from Google, Wikipedia, Elsevier, PubMed, Google scholar, Sci-Hub etc. This is a meta-analysis study. Fluoxetine have the longest half-life, but Fluvoxamine have short half-life. SSRIs increase the serum concentrations of the latter two drugs, potentiating their effects and increasing the risk of toxicity. Fluoxetine and Paroxetine specifically, are known to cause a 5-fold increa...
Asian Journal of Pharmaceutical Research and Development, 2019
A safety signal is data or information that may suggest a new causal association, or contribute n... more A safety signal is data or information that may suggest a new causal association, or contribute new information about a known association, between a medicine and an adverse event that justifies further investigation. Signals are generated from several sources such as spontaneous reports, clinical studies and the scientific literature. Signal is a potential medicine safety issues, which are derived from individual case safety reports in vigiBase. Signal detection is a cornerstone of drug development process ensuring drug safety. The early detection of Signals helps to improve patient safety and reduce economic burden due to escalating cost of medications and unwanted adverse effects associated with it. The present study is an initiative to make significant contribution towards health-care system by generating evidence based data to benefit health care professionals, consumers, pharmaceutical companies and regulatory authorities.Signal detection and signal strengthening is the most im...
Saudi Journal of Medical and Pharmaceutical Sciences, 2020
The endeavor of this online exploratory study was to describe and evaluate the self-medication pr... more The endeavor of this online exploratory study was to describe and evaluate the self-medication practices, reasons behind self-medication, use of antibiotics without prescription among pharmacy graduates in India. The area of interest for the survey is in a students from the "Pharmacy students in Roorkee Dist. Haridwar" using a Sami-structured questionnaire. Data concerning demographic characteristics, medication use habit, and self-medication were collected thought a selfreported questionnaire with open and closed-ended questions. Prior to answering the questionnaire, the students were given a brief explanation about the intention of the study. The choice of question as well as the list of symptoms that might have been self-medicated was based on the findings of previous studies. Medication knowledge was evaluated by the number of correct answer. A students study was conducted in March 2015 with in 100 students from pharmacy fields to test the instrument, determine application time, and clarify question from the students. The issue of self-medication should be addressed by the respective Pharmacy council and other health authorities of India.
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Papers by Deovrat Kumar