Andreea Cernat

Academia de Studii Economice, Business and Turism, Undergraduate

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Numerical study of aerodynamic effects on road vehicles lifting surfaces

Nucleation and Atmospheric Aerosols, 2017

The aerodynamic performance analysis of road vehicles depends on the study of engine intake and c... more The aerodynamic performance analysis of road vehicles depends on the study of engine intake and cooling flow, internal ventilation, tire cooling, and overall external flow as the motion of air around a moving vehicle affects all of its components in one form or another. Due to the complex geometry of these, the aerodynamic interaction between the various body components is significant, resulting in vortex flow and lifting surface shapes. The present study, however focuses on the effects of external aerodynamics only, and in particular on the flow over the lifting surfaces of a common compact car, designed especially for this study.

Modern Analytical Techniques for Detection of Bacteria in Surface and Wastewaters

Zenodo (CERN European Organization for Nuclear Research), Jun 28, 2021

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Sensitive detection of cathinones and their adulterants in street samples using electrochemical fingerprinting

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Staphylococcus aureus – Review on potential targets for sensors development

Bioelectrochemistry

Tackling the issue of healthcare associated infections through point-of-care devices

TrAC Trends in Analytical Chemistry

Proof of Concept for the Detection with Custom Printed Electrodes of Enterobactin as a Marker of Escherichia coli

International Journal of Molecular Sciences

The rapid and decentralized detection of bacteria from biomedical, environmental, and food sample... more The rapid and decentralized detection of bacteria from biomedical, environmental, and food samples has the capacity to improve the conventional protocols and to change a predictable outcome. Identifying new markers and analysis methods represents an attractive strategy for the indirect but simpler and safer detection of pathogens that could replace existing methods. Enterobactin (Ent), a siderophore produced by Escherichia coli or other Gram-negative bacteria, was studied on different electrode materials to reveal its electrochemical fingerprint—very useful information towards the detection of the bacteria based on this analyte. The molecule was successfully identified in culture media samples and a future goal is the development of a rapid antibiogram. The presence of Ent was also assessed in wastewater and treated water samples collected from the municipal sewage treatment plant, groundwater, and tap water. Moreover, a custom configuration printed on a medical glove was employed t...

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Recent approaches to the synthesis of smart nanomaterials for nanodevices in disease diagnosis

Nanomaterials in Diagnostic Tools and Devices

Abstract Noninvasive analysis and presymptomatic molecular diagnosis are the most important for p... more Abstract Noninvasive analysis and presymptomatic molecular diagnosis are the most important for predictive and preventive medicine, allowing earlier disease diagnosis and therapy instauration, reduced cost to healthcare systems, and improved prognosis and better quality of life. Most molecular biomarkers, indicating the state of disease by their presence or high concentration, are larger biomolecules such as proteins, microRNAs, and damaged DNAs; therefore there is a need to develop miniaturized and portable point-of-care devices, with fast analytical response and high selectivity and good sensitivity, ease of use, biocompatibility, and noninvasiveness for use in the biomedical field. Today, micro/nanotechnology is a very active research area to discover new and more efficient smart nanomaterials to be used or applied in wearable and imprinted sensing devices, flexible optoelectronics, artificial intelligence, self-heating, antimicrobial coatings and nanofilms, nanophotonics, optogenetics, and energy harvesting systems. Nanomaterials, such as inorganic and organic nanoparticles, carbon-based nanomaterials and nanocomposites, nanosized and nanostructured polymeric films, and other 3D nanomaterials (e.g., silica-based nanomaterials, molecularly imprinted polymers, metal organic frames, nanomotors, nanorobots), have been widely used for the development of biosensors integrated into diagnostic nanodevices. Recent approaches for the synthesis and functionalization of the most important smart nanomaterials are discussed and future trends and perspectives are emphasized.

深共晶溶媒を用いたテンプレートフリー電気化学合成によるビスマスナノワイヤを含む過酸化水素の検出【JST・京大機械翻訳】

Electrochemistry Communications, 2020

Magnetic nanomaterials-based biosensors

Nanosensors for Smart Agriculture, 2022

Electrochemical Fingerprints of Illicit Drugs on Graphene and Multi-Walled Carbon Nanotubes

Frontiers in Chemistry, 2021

Illicit drugs use and abuse remains an increasing challenge for worldwide authorities and, theref... more Illicit drugs use and abuse remains an increasing challenge for worldwide authorities and, therefore, it is important to have accurate methods to detect them in seized samples, biological fluids and wastewaters. They are recently classified as the latest group of emerging pollutants as their consumption increased tremendously in recent years. Nanomaterials have gained much attention over the last decade in the development of sensors for a myriad of applications. The applicability of these nanomaterials, functionalized or not, significantly increases and it is therefore highly suitable for use in the detection of illicit drugs. We have assessed the suitability of various nanoplatforms, such as graphene (GPH), multi-walled carbon nanotubes (MWCNTs), gold nanoparticles (AuNPs) and platinum nanoparticles (PtNPs) for the electrochemical detection of illicit drugs. GPH and MWCNTs were chosen as the most suitable platforms and cocaine, 3,4-methylendioxymethamfetamine (MDMA), 3-methylmethca...

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Biomedical and Environmental Analysis

New Electrochemical Sensors Based on Clay and Carbon Micro and Nanoparticles for Pharmaceutical and Environmental Analysis

Particle size separation and refinement, followed by physico-chemical characterization studies of... more Particle size separation and refinement, followed by physico-chemical characterization studies of two Romanian bentonites were perfomed. The electrochemical behavior of several pharmaceuticals and heavy metals was tested on clay-modified carbon paste electrodes (CPEs) and glassy carbon electrodes (GCEs) with different clay particle sizes using cyclic voltammetry (CV), square wave voltammetry (SWV) and amperometry. A biosensor based on horseradish peroxidase (HRP) immobilization in a polyetylenimine (PEI) and clay porous gel film for acetaminophen detection was successfully obtained. GCEs modified with clay and PEI or polypyrrole films were also tested for the trace metal analysis using CV and SWV with good results. Polypyrrole films, polystyrene spheres and carboxylated MWCNTs were deposed on graphite electrodes and characterized in order to develop a nitrate reductase biosensor.

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Electrochemical Peptide-Based Sensors for Foodborne Pathogens Detection

Molecules, 2021

Food safety and quality control pose serious issues to food industry and public health domains, i... more Food safety and quality control pose serious issues to food industry and public health domains, in general, with direct effects on consumers. Any physical, chemical, or biological unexpected or unidentified food constituent may exhibit harmful effects on people and animals from mild to severe reactions. According to the World Health Organization (WHO), unsafe foodstuffs are especially dangerous for infants, young children, elderly, and chronic patients. It is imperative to continuously develop new technologies to detect foodborne pathogens and contaminants in order to aid the strengthening of healthcare and economic systems. In recent years, peptide-based sensors gained much attention in the field of food research as an alternative to immuno-, apta-, or DNA-based sensors. This review presents an overview of the electrochemical biosensors using peptides as molecular bio-recognition elements published mainly in the last decade, highlighting their possible application for rapid, non-de...

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Applications of magnetic hybrid nanomaterials in Biomedicine

Biopolymeric Nanomaterials, 2021

New Materials for the Construction of Electrochemical Cell-Based Biosensors

Handbook of Cell Biosensors, 2021

Nanocomposite-based electrochemical platforms for pharmaceutical and environmental applications

Proceedings of The 1st International Electronic Conference on Biosensors, 2020

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Detection of cocaine and cathinones by electrochemical fingerprinting using nanomaterials

Proceedings of The 1st International Electronic Conference on Biosensors, 2020

Illicit drugs use and abuse remains an increasing challenge for worldwide authorities and, theref... more Illicit drugs use and abuse remains an increasing challenge for worldwide authorities and, therefore, it is important to have accurate methods to detect them in seized samples, biological fluids and wastewaters. Nanomaterials have gained much attention over the last decade in the development of sensors for a myriad of applications. The applicability of these nanomaterials, functionalized or not, significantly increases and are therefore highly suitable for use in the detection of drugs of abuse. We have assessed the suitability of various nanoplatforms for the electrochemical detection of illicit drugs, such as graphene, singledwalled carbon nanotubes, multi-walled carbon nanotubes, gold nanoparticles and platinum nanoparticles. Gold and platinum nanoparticles were deposited by electrodeposition from a solution of chloroauric acid and chloroplatinic acid, respectively, by cyclic voltammetry. The electrochemical fingerprints of cocaine and cathinones were elucidated on the above-mentioned nanoplatforms. Square wave voltammetry was performed as a high-performance electrochemical method. This allowed for the sensitive and selective (class selectivity) of the investigated illicit drugs.

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Sensitive detection of cathinones and their adulterants in street samples using electrochemical fingerprinting

Proceedings of The 1st International Electronic Conference on Biosensors, 2020

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Detection of hydrogen peroxide involving bismuth nanowires via template-free electrochemical synthesis using deep eutectic solvents

Electrochemistry Communications, 2020

PrEP improvements in HIV prevention (as an "add-on" strategy) generate safety and economic concer... more

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Tackling the Problem of Sensing Commonly Abused Drugs Through Nanomaterials and (Bio)Recognition Approaches

Frontiers in Chemistry, 2020

We summarize herein the literature in the last decade, involving the use of nanomaterials and var... more We summarize herein the literature in the last decade, involving the use of nanomaterials and various (bio)recognition elements, such as antibodies, aptamers and molecularly imprinted polymers, for the development of sensitive and selective (bio)sensors for illicit drugs with a focus on electrochemical transduction systems. The use and abuse of illicit drugs remains an increasing challenge for worldwide authorities and, therefore, it is important to have accurate methods to detect them in seized samples, biological fluids and wastewaters. They are recently classified as the latest group of "emerging pollutants," as their consumption has increased tremendously in recent years. Nanomaterials, antibodies, aptamers and molecularly imprinted polymers have gained much attention over the last decade in the development of (bio)sensors for a myriad of applications. The applicability of these (nano)materials, functionalized or not, has significantly increased, and are therefore highly suitable for use in the detection of drugs. Lately, such functionalized nanoscale materials have assisted in the detection of illicit drugs fingerprints, providing large surface area, functional groups and unique properties that facilitate sensitive and selective sensing. The review discusses the types of commonly abused drugs and their toxicological implications, classification of functionalized nanomaterials (graphene, carbon nanotubes), their fabrication, and their application on real samples in different fields of forensic science. Biosensors for drugs of abuse from the last decade's literature are then exemplified. It also offers insights into the prospects and challenges of bringing the functionalized nanobased technology to the end user in the laboratories or in-field.

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